Browsing Makale Koleksiyonu by Title
Now showing items 14-33 of 79
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Computational modeling of vascular growth in patient-specific pulmonary arterial patch reconstructions
(Elsevier Ltd, 2021)Recent progress in vascular growth mechanics has involved the use of computational algorithms to address clinical problems with the use of three-dimensional patient specific geometries. The objective of this study is to ... -
Curcumin- and Piperine-loaded emulsomes as combinational treatment approach enhance the anticancer activity of Curcumin on HCT116 colorectal cancer model
(Frontiers in Bioengineering and Biotechnology, 2020)Combination chemotherapy, administrating two chemotherapeutic agents concurrently, comes into prominence, as the heterogeneity or the level of the disease necessitates a collaborative action. Curcumin, isolated from turmeric, ... -
Cytotoxicity of standardized curcuminoids mixture against epithelial ovarian cancer cell line SKOV-3
(MDPI, 2020)Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its therapeutic agents in modern medicine is currently being studied. Curcuminoids are an example of natural agents, ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell
(Springer, 2023)Background: Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
Design of dense brush conformation bearing gold nanoparticles as theranostic agent for cancer
(Springer, 2019)Dense brush conformation–bearing theranostic agents are emerging as drug delivery systems due to their higher ability to escape from reticuloendothelial system uptake which prolongs their in vivo circulation time. With the ... -
Development of acoustically active nanocones using the host-guest interaction as a new histotripsy agent
(American Chemical Society, 2019)Histotripsy is a noninvasive and nonthermal ultrasound ablation technique, which mechanically ablates the tissues using very short, focused, high-pressured ultrasound pulses to generate dense cavitating bubble cloud. ... -
DU 145 insan prostat kanseri hücrelerinde Hsa-Mir-8072’nin potansiyel rolü
(Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2019)Amaç: Çalışmamızda, insan prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında miRNA ifadesinin analizini yapmak ve kanser gelişiminde olası rolünü incelemeği amaçladık. Gereçler ve ... -
Effect of a pedicle screw fixation system on lumbar spinal segments: A finite element study
(2023)Objective: Spinal implants have been used to stimulate fusion by surgical adjustment and correct abnormal alignment of the vertebral column. Spinal fusion can cause some spinal disorders and hence describing the changes ... -
The effect of PEGylation components on drug release behavior of targeted reduced graphene oxide based drug delivery system
(2024)Reduced graphene oxide (rGO) is a restored, defect-free version of graphene oxide (GO) with regained graphene-like properties but encounters challenges in biomedical applications due to its low solubility. Especially for ... -
Effective PEGylation method to improve biocompatibility of graphene derivatives
(Elsevier, 2020)The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ... -
Effects of bone surface topography and chemistry on macrophage polarization
(2024)Surface structure plays a crucial role in determining cell behavior on biomaterials, influencing cell adhesion, proliferation, differentiation, as well as immune cells and macrophage polarization. While grooves and ridges ... -
Effects of droplet composition on nanodroplet-mediated histotripsy
(Elsevier Science Inc, 2016)Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane ... -
Effects of ultrasound frequency on nanodroplet-mediated histotripsy
(Elsevier Science, 2015)Nanodroplet-mediated histotripsy (NMH) is a targeted ultrasound ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells for targeted tumor ablation. In a previous study, ... -
The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions
(Springer Nature, 2022)Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ... -
Emulsomes meet s-layer proteins: An emerging targeted drug delivery system
(Bentham Science Publishers, 2015)Here, the use of emulsomes as a drug delivery system is reviewed and compared with other similar lipidic nanoformulations. In particular, we look at surface modification of emulsomes using S-layer proteins, which are ... -
Enhancing enzymatic properties of endoglucanase i enzyme from trichoderma reesei via swapping from cellobiohydrolase i enzyme
(MDPI, 2019)Utilizing plant-based materials as a biofuel source is an increasingly popular attempt to redesign the global energy cycle. This endeavour underlines the potential of cellulase enzymes for green energy production and ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
(American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Exploiting stokes and anti-stokes type emission profiles of aptamer-functionalized luminescent nanoprobes for multiplex sensing applications
(Wiley-VCH Verlag Gmbh, 2018)Multiplex biosensing of four types of bacterial food pathogens in one pot is described. Stokes and anti-Stokes type photoluminescence (PL) of two quantum dots (QD) and two upconverting nanoparticles (UCNP) were utilised ... -
Fast and flexible packed string matching
(Elsevier, 2014)Searching for all occurrences of a pattern in a text is a fundamental problem in computer science with applications in many other fields, like natural language processing, information retrieval and computational biology. ... -
Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
(Amer Chemical Soc, 2016)We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ...