• Microwave-promoted continuous flow systems in nanoparticle synthesis-A perspective 

  Saleem, Qandeel; Torabfam, Milad; Fidan, Tuçe; Kurt, Hasan; Yüce, Meral; Clarke, Nigel; Bayazıt, Mustafa Kemal (American Chemical Society, 2021)

  Microwave-promoted continuous flow systems have emerged as a game-changer in nanoparticle synthesis. Owing to the excellent compatibility between fast, sustainable microwave heating and one-step, efficient flow chemistry, ...

• Sağlık teknolojisi değerlendirmede çok kriterli karar verme yaklaşımları üzerine bir derleme çalışması 

  Almula Karadayı, Melis; Yılmaz, Beyza Özlem; Erol, Bilgehan Eren; Tozan, Hakan (Düzce Üniversitesi, 2020)

  Sağlık sektöründe yer alan ilaçlar, tıbbi tedavi prosedürleri, tıbbı cihazlar, cerrahi teknikler ve sağlık sistemleri Sağlık Teknolojisi Değerlendirme (STD) kapsamında değerlendirilmektedir. Bu tip sağlık teknolojilerinin ...

• An MCDM-based health technology assessment (HTA) study for evaluating kidney stone treatment alternatives 

  Erol, Eren; Yılmaz, Beyza Özlem; Almula Karadayı, Melis; Tozan, Hakan (Springer Science and Business Media Deutschland GmbH, 2021)

  The prevalence of kidney stone disease has increased during the last decade due to various reasons such as changes in dietary and water consumption. To overcome this issue, new treatment approaches are being developed. ...

• Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei 

  Edsall, Connor; Khan, Zerin Mahzabin; Mancia, Lauren; Hall, Sarah; Mustafa, Waleed; Johnsen, Eric; Klibanov, Alexander L.; Yüksel Durmaz, Yasemin; Vlaisavljevich, Eli (Elsevier Science Inc, 2021)

  The study described here examined the effects of cavitation nuclei characteristics on histotripsy. Highspeed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ...

• Öğrenci mikroskobunda epifloresan görüntüleme 

  Gökduman, Selcen Necibe (Institute of Electrical and Electronics Engineers Inc., 2020)

  Fluorescence microscopy is used as an important tool for research and education in the biological sciences. Fluorescence microscopes allow fluorescent signal to be obtained by stimulating markers in biological samples using ...

• Quantitative phase macroscopic system for label-free imaging of tissue sections 

  Toy, Muhammed Fatih (İstanbul University, 2021)

  Optical microscopes are typically designed as versatile tools that are capable of imaging at various modalities with different resolutions in respective visual fields. A large extend of versatility causes increased complexity, ...

• Computational modeling of vascular growth in patient-specific pulmonary arterial patch reconstructions 

  Lashkarinia, S. Samaneh; Çoban, Gürsan; Köse, Banu; Salihoğlu, Ece; Pekkan, Kerem (Elsevier Ltd, 2021)

  Recent progress in vascular growth mechanics has involved the use of computational algorithms to address clinical problems with the use of three-dimensional patient specific geometries. The objective of this study is to ...

• A mobile parallel manipulator for the elbow rehabilitation of parkinsonian patients 

  Gül, Rabia; Şener, Şaika; Hocaoǧlu, Elif (Institute of Electrical and Electronics Engineers Inc., 2020)

  This study presents a two degrees of freedom (DoF) parallel manipulator that enables Parkinsonian Patients to regularly do the assigned rhythmic tasks in order to reduce the symptoms of motor disorders. Considering the ...

• Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model 

  Yılmaz, Elif Nur; Bay, Sadık; Öztürk, Gürkan; Uçışık, Mehmet Hikmet (Dove Medical Press Ltd, 2020)

  Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ...

• DU 145 insan prostat kanseri hücrelerinde Hsa-Mir-8072’nin potansiyel rolü 

  Ayla, Şule; Parlayan, Cüneyd; Karakaş, Nihal; Açıkgöz, Eda; Öktem, Gülperi (Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2019)

  Amaç: Çalışmamızda, insan prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında miRNA ifadesinin analizini yapmak ve kanser gelişiminde olası rolünü incelemeği amaçladık. Gereçler ve ...

• Cytotoxicity of standardized curcuminoids mixture against epithelial ovarian cancer cell line SKOV-3 

  Almosa, Heba; Alqriqri, Mihal; Denetiu, Iuliana; Baghdadi, Mohammed Abbas; Alkhaled, Mohammed; Alhosin, Mahmoud; Aldajani, Wejdan A.; Zamzami, Mazin; Üçışık, Mehmet Hikmet (MDPI, 2020)

  Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its therapeutic agents in modern medicine is currently being studied. Curcuminoids are an example of natural agents, ...

• Scattering metal waveguide based speckle-enhanced prism spectrometry 

  Çetindağ, Şakir Kaan; Toy, Muhammed Fatih; Ferhanoğlu, Onur; Çivitci, Fehmi (IEEE - Institute of Electrical and Electronics Engineers, Inc., 2020)

  We present an optical efficiency improved speckle spectrometer where a scattering metal wave-guide is utilized along with a conventional prism spectrometer. We conducted extensive tests on 25 different scatterers, involving ...

• Proteomic study of hepatocellular carcinoma using a novel modified aptamer-based array (SOMAscan (TM)) platform 

  Qiao, Zhiwei; Pan, Xiaoqing; Parlayan, Cüneyd; Ojima, Hidenori; Kondo, Tadashi (Elsevier Science, 2017)

  Vascular invasion is a pathological hallmark of hepatocellular carcinoma (HCC), associated With poor prognosis; it is strongly related to the early recurrence and poor survival after curative resection. In order to determine ...

• Curcumin- and Piperine-loaded emulsomes as combinational treatment approach enhance the anticancer activity of Curcumin on HCT116 colorectal cancer model 

  Bolat, Zeynep Büşra; İşlek, Zeynep; Demir, Bilun Nas; Yılmaz, Elif Nur; Şahin, Fikrettin; Üçışık, Mehmet Hikmet (Frontiers in Bioengineering and Biotechnology, 2020)

  Combination chemotherapy, administrating two chemotherapeutic agents concurrently, comes into prominence, as the heterogeneity or the level of the disease necessitates a collaborative action. Curcumin, isolated from turmeric, ...

• Hücre dışı sinirsel kayıtlarda olabilirliǧe dayalı genlik eşikleme 

  Dağdevir, Eda; Kocatürk, Mehmet; Okatan, Murat (Institute of Electrical and Electronics Engineers Inc., 2019)

  Hücre dışı sinirsel kayıtlarda genlik eşiğinin optimizasyonu son zamanlarda beyin-makine arayüzü literatüründe etkin bir araştırma konusu haline gelmiştir. Önceki bir çalışmada, davranış değişkenlerinin sinirsel etkinlikte ...

• Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis 

  Keskin, Elif; Üçışık, Mehmet Hikmet; Sucu, Bilgesu Onur; Güzel, Mustafa (MDPI, 2019)

  Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ...

• Integrative analysis of axolotl gene expression data from regenerative and wound healing limb tissues 

  Sibai, Mustafa; Parlayan, Cüneyd; Tuğlu, Pelin; Öztürk, Gürkan; Demircan, Turan (Nature Research, 2019)

  Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ...

• Design of dense brush conformation bearing gold nanoparticles as theranostic agent for cancer 

  Verimli, Nihan; Demiral, Ayşegül; Yılmaz, Hülya; Çulha, Mustafa; Erdem, Sultan Sibel (Springer, 2019)

  Dense brush conformation–bearing theranostic agents are emerging as drug delivery systems due to their higher ability to escape from reticuloendothelial system uptake which prolongs their in vivo circulation time. With the ...

• Speckle-enhanced prism spectrometer 

  Çetindağ, Şakir Kaan; Ferhanoğlu, Onur; Toy, Muhammed Fatih; Çivitçi, Fehmi (IEEE Computer Society, 2019)

  We present an improved prism spectrometer with high wavelength range and spectral resolution. The device is an upgraded prism spectrometer that utilizes an additional scattering medium leading to a wavelength-dependent ...

• Effective PEGylation method to improve biocompatibility of graphene derivatives 

  Demirel, Erhan; Karaca, Ezgi; Yüksel Durmaz, Yasemin (Elsevier, 2020)

  The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ...

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