• A 3-DoF robotic platform for the rehabilitation and assessment of reaction time and balance skills of MS patients 

  Ersoy, Tuğçe; Hocaoğlu, Elif (Public Library of Science, 2023)

  The central nervous system (CNS) exploits anticipatory (APAs) and compensatory (CPAs) postural adjustments to maintain the balance. The postural adjustments comprising stability of the center of mass (CoM) and the pressure ...

• Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a 

  Çapkın, Eda; Kurt, Hasan; Gürel, Büşra; Bıçak, Dilan; Akgün Baş, Sibel; Dağlıkoca, Duygu Emine; Yüce, Meral (American Chemical Society, 2022)

  Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ...

• Oxide glass formers extending persistent luminescence in Eu and Dy co-doped strontium aluminates 

  Coşgun Ergene, Arzu; Khabbaz Abkenar, Sirous; Şenol Güngör, Ayça; Günay, Ece; Kurt, Hasan; Topçu, Gökhan; Ow-Yang, Cleva W. (Elsevier B.V., 2023)

  Recent work has shown that the incorporation of electrically charged, non-bridging oxygen (NBO) species into Eu and Dy co-doped Sr4Al14O25 (S4A7ED) crystal structure, in the form of BØ2O−, induces the clustering of divalent ...

• Biomechanical study on three screw-based atlantoaxial fixation techniques: A finite element study 

  Erbulut, Deniz Ufuk; Mumtaz, Muzammil; Zafarparandeh, Iman; Özer, Ali Fahir (Korean Society of Spine Surgery, 2022)

  Study Design: This is a finite element study. Purpose: This study is aimed to compare the biomechanical behaviors of three screw-based atlantoaxial fixation techniques. Overview of Literature: Screw-based constructs that ...

• The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions 

  Pishva, Parsa; Bayazıt, Mustafa Kemal; Kurt, Hasan; Yüce, Meral (Springer Nature, 2022)

  Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ...

• A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media 

  Altınkök, Çağatay; Sağdıç, Gökhan; Dağlar, Özgün; Ercan Ayra, Merve; Yüksel Durmaz, Yasemin; Durmaz, Hakan; Açık, Gökhan (Elsevier Ltd, 2023)

  Phosphorylated poly(vinyl chloride) (PPVC)/polyethyleneimine (PEI)-based nanofibers were produced via electrospinning in their blended solutions for the first time. For this purpose, PVC was partially converted into PVC-N3 ...

• Radiation type- and dose-specific transcriptional responses across healthy and diseased mammalian tissues 

  Sagkrioti, Eftychia; Biz, Gökay Mehmet; Takan, Işıl; Asfa, Seyedehsadaf; Nikitaki, Zacharenia; Zanni, Vassiliki; Kars, Rümeysa Hanife; Hellweg, Christine E.; Azzam, Edouard I.; Logotheti, Stella; Pavlopoulou, Athanasia; Georgakilas, Alexandros G. (MDPI, 2022)

  Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but ...

• Plasmonic enhancement in PTB7-Th:PC71BM organic photovoltaics 

  Kurt, Hasan (Elsevier B.V., 2022)

  Organic photovoltaics struggles with limited exciton diffusion rate and low light absorption rates. The trade-off between these deficiencies limits the thickness of the active layer around 100–200 nm range. Plasmonic light ...

• Characterization and biological evaluation of crataegus azarolus fruit polysaccharides 

  Bensaci, Narimen; Abdi, Akila; Aziza, Haifa Ben; Aouadi, Saoudi (Elsevier B.V., 2022)

  The polysaccharide obtained from Crataegus azarolus fruit, by water extraction followed by ethanol precipitation and fractionation using copper complex, shows physiological activities: prebiotic and antioxidant. The total ...

• Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents 

  Kaymaz, Betül; Mustafa, Waleed; Hall, Sarah; Vlaisavljevich, Eli; Şensoy, Özge; Yüksel Durmaz, Yasemin (American Chemical Society, 2022)

  Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ...

• SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers 

  Yılmaz, Deniz; Muslu, Tuğdem; Parlar, Ayhan; Kurt, Hasan; Yüce, Meral (Elsevier B.V., 2022)

  Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial libraries through an iterative in vitro screening process known as Systemic Evolution of Ligands by Exponential Enrichment (SELEX). In ...

• Investigation of 3D-printed chitosan-xanthan gum patches 

  Altan, Eray; Türker, Nurgül; Hindy, Osama Ali; Dirican, Zeynep; Bingöl Özakpınar, Özlem; Uzuner Demir, Ayşegül; Kalaskar, Deepak; Thakur, Sourbh; Gündüz, Oğuzhan (Elsevier B.V., 2022)

  In this study, using a new polymer combination of Chitosan(CH)/Xanthan Gum(XG) has been exhibited for wound dressing implementation by the 3D-Printing method, which was fabricated due to its biocompatible, biodegradable, ...

• A novel fontan Y-graft for interrupted inferior vena cava and azygos continuation 

  Lashkarinia, S. Samaneh; Çiçek, Murat; Köse, Banu; Rezaeimoghaddam, Mohammad; Hekim Yılmaz, Emine; Aydemir, Numan Ali; Rasooli, Reza; Özkök, Serçin; Yurtseven, Nurgül; Erdem, Hasan; Pekkan, Kerem; Şaşmazel, Ahmet (Elsevier Science, 2022)

  Objectives: To evaluate the hemodynamicdynamic advantage of a new Fontan surgical template that is intended for complex single-ventricle patients with interrupted inferior vena cava-azygos and hemi-azygos continuation. The ...

• In vitro measurement of hepatic flow distribution in Fontan vascular conduits: Towards rapid validation techniques 

  Rasooli, Reza; Köse, Kevser Banu; Lashkarinia, S. Samaneh; Şaşmazel, Ahmet; Pekkan, Kerem (Elsevier Ltd, 2022)

  Fontan operation is the last stage of single-ventricle surgical reconstructions that connects superior and inferior vena cava (SVC, IVC) to the pulmonary arteries. The key design objectives in total cavopulmonary connections ...

• Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab 

  Sert, Fatma; Hız, Defne; Gülmez, Mert; Cankurtaran, Selen Ezgi; Kayalan, Cemre Irmak; Kurt, Hasan; Yüce, Meral (MDPI, 2022)

  The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ...

• A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task 

  Zaidi, Syed Muhammad Talha; Kocatürk, Samet; Baykaş, Tunçer; Kocatürk, Mehmet (Elsevier B.V., 2022)

  Background: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet. New method: Here, we describe ...

• Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer 

  Mansoor, Samman; Kayık, Gülru; Durdağı, Serdar; Şensoy, Özge (Elsevier B.V., 2022)

  Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ...

• Antileishmanial activity of BNIPdaoct- and BNIPdanon-loaded emulsomes on leishmania infantum parasites 

  İşlek, Zeynep; Üçışık, Mehmet Hikmet; Keskin, Elif; Onur Sucu, Bilgesu; Gomes-Alves, Ana G.; Tomás, Ana M.; Güzel, Mustafa; Şahin, Fikrettin (Frontiers Media S.A., 2022)

  Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ...

• Investigation into cervical spine biomechanics following single, multilevel and hybrid disc replacement surgery with dynamic cervical implant and fusion: A finite element study 

  Mumtaz, Muzammil; Zafarparandeh, Iman; Erbulut, Deniz Ufuk (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Cervical fusion has been a standard procedure for treating abnormalities associated with the cervical spine. However, the reliability of anterior cervical discectomy and fusion (ACDF) has become arguable due to its adverse ...

• Can Carpobrotus edulis, heal incisional and excisional wounds on the skin? 

  Günal, Mehmet Yalçın; Şahinler Ayla, Sibel; Çaglayan, Berrak; Beker, Mustafa Çağlar; Bedri, Nejda; Aslan, İpek Bilge; Özdemir, Ekrem Musa; Kılıç, Ertuğrul; Yeşilada, Elif (Comenius University, 2021)

  OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis powder extract (CEPE) formulation on incisional and excisional wounds in rat. BACKGROUND: In the event of any damage, ...

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