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The effect of PEGylation components on drug release behavior of targeted reduced graphene oxide based drug delivery system
(2024)Reduced graphene oxide (rGO) is a restored, defect-free version of graphene oxide (GO) with regained graphene-like properties but encounters challenges in biomedical applications due to its low solubility. Especially for ... -
Effective PEGylation method to improve biocompatibility of graphene derivatives
(Elsevier, 2020)The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ... -
Effects of bone surface topography and chemistry on macrophage polarization
(2024)Surface structure plays a crucial role in determining cell behavior on biomaterials, influencing cell adhesion, proliferation, differentiation, as well as immune cells and macrophage polarization. While grooves and ridges ... -
Effects of droplet composition on nanodroplet-mediated histotripsy
(Elsevier Science Inc, 2016)Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane ... -
Effects of ultrasound frequency on nanodroplet-mediated histotripsy
(Elsevier Science, 2015)Nanodroplet-mediated histotripsy (NMH) is a targeted ultrasound ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells for targeted tumor ablation. In a previous study, ... -
The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions
(Springer Nature, 2022)Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ... -
Emulsomes meet s-layer proteins: An emerging targeted drug delivery system
(Bentham Science Publishers, 2015)Here, the use of emulsomes as a drug delivery system is reviewed and compared with other similar lipidic nanoformulations. In particular, we look at surface modification of emulsomes using S-layer proteins, which are ... -
Enhancing enzymatic properties of endoglucanase i enzyme from trichoderma reesei via swapping from cellobiohydrolase i enzyme
(MDPI, 2019)Utilizing plant-based materials as a biofuel source is an increasingly popular attempt to redesign the global energy cycle. This endeavour underlines the potential of cellulase enzymes for green energy production and ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
(American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Exploiting stokes and anti-stokes type emission profiles of aptamer-functionalized luminescent nanoprobes for multiplex sensing applications
(Wiley-VCH Verlag Gmbh, 2018)Multiplex biosensing of four types of bacterial food pathogens in one pot is described. Stokes and anti-Stokes type photoluminescence (PL) of two quantum dots (QD) and two upconverting nanoparticles (UCNP) were utilised ... -
Fast and flexible packed string matching
(Elsevier, 2014)Searching for all occurrences of a pattern in a text is a fundamental problem in computer science with applications in many other fields, like natural language processing, information retrieval and computational biology. ... -
Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
(Amer Chemical Soc, 2016)We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ... -
How to reduce stress on the pedicle screws in thoracic spine? Importance of screw trajectory: A finite element analysis
(Turkish Neurosurgical Society, 2019)AIM: To investigate the biomechanical comparison of thoracic transpedicular screw trajectories on the sagittal plane. MATERIAL and METHODS: A three-dimensional, non-linear finite element analysis (FEA) model of T8 through ... -
Hydrothermal performance of mini-channel heat sink using nanofluids/hybrid nanofluids: a numerical study
(2024)We investigated hydrothermal performance of the mini-channel heat sink by using water, and nanofluids/hybrid nanofluids at 1% of volumetric concentration. The water-based nanofluids studied in this work were CuO, TiO2 and ... -
In vitro measurement of hepatic flow distribution in Fontan vascular conduits: Towards rapid validation techniques
(Elsevier Ltd, 2022)Fontan operation is the last stage of single-ventricle surgical reconstructions that connects superior and inferior vena cava (SVC, IVC) to the pulmonary arteries. The key design objectives in total cavopulmonary connections ... -
In-situ measurement of anisotropic Young’s modulus in fused deposition modeling printed cantilevers
(IOP Publishing Ltd, 2023)In this study, we investigate the effect of fused deposition modeling printing direction on the effective Young's modulus value of cantilevers. Through finite-element simulations and experiments with seven different ... -
Influence of three-dimensional reconstruction method for building a model of the cervical spine on its biomechanical responses: A finite element analysis study
(Hindawi Publishing Corporation, 2016)In some finite element analysis studies of models of sections of the spine, the three-dimensional solid model is built by assuming symmetry about the mid-sagittal plane of the section, whereas in other studies, the model ... -
Investigation into cervical spine biomechanics following single, multilevel and hybrid disc replacement surgery with dynamic cervical implant and fusion: A finite element study
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Cervical fusion has been a standard procedure for treating abnormalities associated with the cervical spine. However, the reliability of anterior cervical discectomy and fusion (ACDF) has become arguable due to its adverse ... -
Investigation of 3D-printed chitosan-xanthan gum patches
(Elsevier B.V., 2022)In this study, using a new polymer combination of Chitosan(CH)/Xanthan Gum(XG) has been exhibited for wound dressing implementation by the 3D-Printing method, which was fabricated due to its biocompatible, biodegradable, ... -
Investigation of optimum production conditions and the stability of β-cyclodextrin-perfluorocarbon nanocone clusters for histotripsy applications
(2024)Nanocone clusters (NCCs) have been developed as clusters with inclusion complexes of FDA-approved β-cyclodextrin (βCD) and perfluorocarbons (PFC) (i.e., perfluoropentane (PFP) and perfluorohexane (PFH)) and have shown ...