Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 280, listelenen: 101-120
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Glyconanoparticles for targeted tumor therapy of platinum anticancer drug
(American Chemical Society, 2019)An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic ... -
Improving therapeutic efficacy of voriconazole against fungal keratitis: Thermo-sensitive in situ gels as ophthalmic drug carriers
(Elsevier Science Bv, 2019)The aim of this research was to evaluate the potential use of in situ gel formulations for voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was applied to increase residence time and ... -
Quality by design approach for optimizing preparation and characterization of buccal film formulation with different polymers
(Advanced Scientific Research, 2019)Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug administration via the oral cavity. Polymeric film formulations containing chitosan, sodium alginate or carbopol were evaluated to ... -
An alternative approach to wound healing field; New composite films from natural polymers for Mupirocin dermal delivery
(Elsevier, 2019)In this study, novel adhesive films were prepared for Mupirocin dermal delivery. Natural polymers as chitosan, sodium alginate and carbopol were used for films development to evaluate possible interactions and drug release ... -
Synthesis and anticancer activity of some 1H-inden-1-one substituted (heteroaryl)acetamide derivatives
(Bentham Science Publishers Ltd., 2019)Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied. Methods: ... -
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
(Marmara University, 2019)The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ... -
Assessment of job satisfaction, work-related strain, and perceived stress in nurses working in different departments in the same hospital: A survey study
(Springer, 2020)ObjectiveWe aimed to evaluate whether working at ICU, inpatient services, or the operating room creates differences in job satisfaction (JS), work-related strain (WRS), and perceived stress (PS) of nurses.Research ... -
Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines
(İstanbul University, 2020)Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root ... -
In vitro anti-helicobacter pylori and antimycobacterial activity evaluation of selected plants from Turkey
(2020)In this study, the extracts of Ulmus minor Mill. subsp. minor (Ulmaceae), Lathyrus pratensis L. (Leguminosae), Glaucium leiocarpum Bois. (Papaveraceae), and Echium vulgare L. (Boraginacea) were investigated for their in ... -
Wound healing effect of naringin gel in alloxan induced diabetic mice
(Ankara University Faculty of Pharmac, 2020)Objective: The aim of this study was to investigate the effects of naringin, a known flavonoid, on in vitro cytotoxicity, irritation and in vivo potential efficacy when topically applied to the diabetic wound. Material and ... -
Matrin ve oksimatrinin mikrobiyal transformasyonu ve metabolitlerinin in vitro biyolojik aktivitelerinin incelenmesi
(Mersin Üniversitesi, 2020)Amaç: Matrin ve oksimatrin bileşiklerinin mikrobiyal transformasyon yolu ile metabolitlerin karşılaştırmalı olarak biyolojik aktivitelerinin incelenmesi hedeflenmiştir. Yöntem:30 farklı mikroorganizmanın sıvı besiyerinde ... -
Antibiotic susceptibility of Klebsiella pneumoniae strains isolated from clinical samples
(Turkish Chemical Society, 2020)Antibiotic resistance in bacteria has become a worrying phenomenon in today's world. K. pneumoniae is a member of the Enterobacteriaceae family, which causes nosocomial infections as an opportunistic pathogen but inherently ... -
Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy
(Royal Society of Chemistry, 2020)Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical applications such as cancer imaging and therapy. CNMs, which are currently used in a wide range of applications, suffer from drawbacks of ... -
Antimicrobial activities of allium staticiforme and allium subhirsutum
(Bangladesh Pharmacological Society, 2020)The antibacterial and antifungal activities of the bulb and flower of Allium statciforme and Allium subhirsutum were investigated. In addition, DPPH radical scavenging activity and total phenolic contents were determined. ... -
Determination of the volatile compounds of anthemis cretica subsp. Anatolica (boiss.) grierson
(Badebio Biotechnololgy Ltd, 2020)Chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Anthemis cretica subsp. anatolica was analyzed by gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS) ... -
Significance of a clinical pharmacist-led comprehensive medication management program for hospitalized oncology patients
(Springer, 2020)Background The use of highly toxic drugs in cancer treatment and supportive care medications exposes patients to an increased number of drug-related problems (DRPs). Clinical pharmacists contribute to the optimal use of ... -
Comparative study of the anti-inflammatory, antioxidant and urease inhibitory activities of Eryngium kotschyi Boiss. and E. campestre L. var. virens (Link) Weins extracts
(Marmara University Press, 2020)Despite widespread traditional usage of Eryngium species in Anatolia (Turkey), only a limited number of scientific studies exists on E. kotschyi, an endemic species. Previously, extracts from E. campestre and E. kotschyi ... -
Non-covalent functionalization of single walled carbon nanotubes with pyrene pendant polyester: A DFT supported study
(Elsevier, 2020)Non-covalent attachment onto single-walled carbon nanotubes (SWCNTs) by protecting nanotubes' intrinsic properties has an important role in development of hybrid composite materials. Herein, we present non-covalent ... -
Identification and in vitro bioactivity screening of some marine-derived fungi from Turkish coastlines
(Cahiers de Biologie Marine, 2020)The marine environment represents a great variety of conditions of pressure, temperature, salinity, and light depending on depth, latitude and interactions with the continental shelf. These extreme and variable conditions ... -
An alternative approach wound healing field with polypodium vulgare
(Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ...