• Evaluation of disease and medication knowledge levels of diabetic patients 

  Umar, Rashida Muhammad; Çattık, Büşra Nur; Aslan, Selim (Istanbul University, 2023)

  Background and Aims: Diabetes mellitus is a public health problem with a significant economic burden to society. Patient attitude is a significant determinant of adherence and clinical outcomes. We aimed to evaluate the ...

• Panax ginseng extract ameliorates methotrexate-induced multi-organ damage via the regulation of oxidative stress 

  Macit, Çağlar; Ede Pazarbaşı, Seren; Yılmaz Karaoğlu, Sümeyye; Tunali Akbay, Tuğba; Karakaya Çimen, Fatma Bedia; Ercan, Feriha; Şener, Göksel (Marmara University, 2023)

  Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and ...

• Traditional herbal drugs against liver diseases – Experimented in vitro using HepG2 cells for induced steatosis 

  Karadağ, Ayşe Esra; Okur, Mehmet Evren; Özhan, Yağmur; Sipahi, Hande; Demirci, Fatih (Marmara University, 2023)

  Salvia fruticosa leaves, Malva sylvestris flowers, Taraxacum officinale aerial parts, Plantago ovata seeds, Tanacetum parthenium aerial parts, and Allium sativum bulbs are documented for traditional use against hepatic ...

• In vitro cytotoxicity evaluation and phytochemical analysis of Ajuga reptans L. extracts 

  Çaşkurlu, Ayşegül; Karavuş, Şule Nur; Biltekin, Sevde Nur; Helvacı, Esra Zeynep; Karadağ, Ayşe Esra (Marmara University, 2023)

  The aim of this study was to evaluate phytochemical composition of Ajuga reptans L. (Lamiaceae) aerial parts (separately flower and leaf) methanol, aqueous-methanolic extracts, and their cytotoxic activities. The phytochemical ...

• Human biomonitoring of trace elements (Zn, Cu, Mn, Cd and As) level in a healthy urban population in Türkiye 

  Söylemez, Esma; Özçağlı, Eren; Göktaş, Eylem Funda; Kürekçi, Fulya; Omurtag, Gülden Zehra (Marmara University, 2023)

  Human biomonitoring (HBM) studies are carried out to examine the effects of environmental pollutants on human health and to identify risks to public health, with the increasing awareness of environmental pollution around ...

• Biological activities of the natural coumarins from apiaceae plants 

  Tosun, Fatma; Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Mıhoğlugil, Feyyaz; Akalgan, Demet; Miski, Mahmut (ACG Publications, 2023)

  Nineteen natural coumarins; badrakemin (1), colladonin (2), 14'-acetoxybadrakemin (3), anatolicin (4), 14'-hydroxycolladonin (5), badrakemone (6), karatavicinol (7), 14'-acetoxybadrakemone (8), 14'-acetoxycolladonin (9), ...

• Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-beta reveals anticancer effect in breast cancer 

  Şalva, Emine; Özbaş, Suna; Alan, Saadet; Özkan, Naziye; Ekentok Atıcı, Ceyda; Kabasakal, Levent; Akbuğa, Jülide (Wiley, 2023)

  Background: Platelet derived growth factors (PDGF)-D and the expression of its receptor increase in neoplastic progression of cancer. Co-silencing of growth factor and receptor can be suggested as an important strategy for ...

• Binary synergistic combinations of lavender and fennel essential oils with amoxicillin 

  Karadaǧ, Ayşe Esra; Çaşkurlu, Ayşegül; Demirci, Betül; Demirci, Fatih (Georg Thieme Verlag, 2023)

  Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations ...

• Nanofiller-based novel hybrid composite membranes for high-capacity lithium-sulfur batteries 

  Dombaycıoğlu, Şeyma; Günsel, Hilal; Aydın, Ali Osman (John Wiley and Sons Inc, 2023)

  Herein, Al2O3 nanofiller-reinforced lithiated Nafion:Aquivion hybrid composite ion-exchange membranes have been produced by mixing lithiated Nafion and Aquivion ionomers. After the electrochemical tests, the Li-Naf : ...

• The anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae) 

  Aydın, Bilge; Yuca, Hafize; Karakaya, Songül; Ekşi Bona, Gülnur; Göger, Gamze; Tekman, Enes; Acar Şahin, Aydan; Sytar, Oksana; Civaş, Ayşe; Canlı, Deniz; Pınar, Nur Münevver; Güvenalp, Zuhal (Springer Wien, 2023)

  Scilla siberica subsp. armena is known as Siberian Squill which is naturally distributed in Lebanon-Syria, Transcaucasus, and Turkey. It is a perennial bulbous plant with a short vegetation period from March to May. In ...

• Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens 

  Hoş, Ayşegül; Omurtag Özgen, Pınar Sinem; İnci, Ayşe; Avcı, Buse; Ceylan, Ceyda (Marmara University, 2023)

  The present study investigated the antibacterial activity of carvacrol against Vancomycin-Resistant Enterococci (VRE), Carbapenem-Resistant Enterobacteriaceae (CRE), Methicillin-Resistant Staphylococcus aureus (MRSA), ...

• Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC. 

  İşcan, Gökalp; Kürkçüoğlu, Mine; Tosun, Fatma; Miski, Mahmut (Istanbul Medipol University, 2023)

  The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were ...

• Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage 

  Karakaya Çimen, Fatma Bedia; Macit, Çağlar; Sivas, Güzin Göksun; Tunalı Akbay, Tuğba; Şener, Göksel; Ercan, Feriha (Istanbul University Press, 2023)

  Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ...

• Effects of chitosan nanoparticles with long synthetic siRNAs targeting VEGF in triple-negative breast cancer cells 

  Cömez, Birnur; Akbuğa, Jülide (Faculdade de Ciencias Farmaceuticas (Biblioteca), 2023)

  Vascular endothelial growth factor (VEGF) is an essential angiogenic factor in breast cancer development and metastasis. Small interfering RNAs (siRNAs) can specifically silence genes via the RNA interference pathway, ...

• Sesquiterpene coumarin ethers with selective cytotoxic activities from the roots of ferula huber-morathii Peşmen (Apiaceae) and unequivocal determination of the absolute stereochemistry of samarcandin 

  Eruçar, Fatma Memnune; Kuran, Fadıl Kaan; Altıparmak Ülbegi, Gülsüm; Özbey, Süheyla; Karavuş, Şule Nur; Arcan, Gülşah Gamze; Yazıcı Tütüniş, Seçil; Tan, Nur; Aksoy Sağırlı, Pınar; Miski, Mahmut (MDPI, 2023)

  Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some folkloric recipes used for cancer treatment also contain the resin of Ferula species. The dichloromethane extract of the roots of ...

• In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol 

  Demirci, Fatih; Teralı, Kerem; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Ak Sakallı, Ezgi; Demirci, Betül; Koşar, Müberra; Başer, Kemal Hüsnü Can (Georg Thieme Verlag KG, 2023)

  Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ...

• Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine 

  Arpa, Muhammet Davut; Üstündağ Okur, Neslihan; Gök, Mehmet Koray; Özgümüş, Saadet; Cevher, Erdal (Elsevier B.V., 2023)

  Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to extensive first-pass metabolism and is ...

• Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage 

  Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers Ltd., 2023)

  Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ...

• Chitosan modification-enhanced silencing effect of Ad5-shPDGF-D vector in breast cancer cell line MDA-MB-231 

  Ekentok Atıcı, Ceyda; Akbuğa, Jülide (Bentham Science Publisher, 2023)

  Background Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because it ...

• In vivo wound-healing and in vitro antibacterial and antioxidant of Carduus extract 

  Şakul, Ayşe Arzu; Ayla, Şule; Okur, Mehmet Evren; Karadağ, Ayşe Esra; Daylan, Benay; Güzel, Elif; Özdemir, Ekrem Musa; Günal, Mehmet Yalçın (Marmara University, 2023)

  Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Turkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ...

View more