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Sprayable microemulsion of diphenhydramine hydrochloride for dermal delivery
(2024)In this work, a sprayable microemulsion of diphenhydramine hydrochloride (DPH HCl) was developed for use in conditions that cause itching, such as insect bites, mild sunburns, and skin irritations. Microemulsions were ... -
HPLC investigation of hidden danger deoxynivalenol (vomitoxin) in baby foods from grain sources in Türkiye
(2024)The Food and Agricultural Organization (FAO) declared that at minimum, one quarter of the earth’s food supply is infected with mycotoxins. Deoxynivalenol (DON) is the most common Fusarium mycotoxin in maize, wheat, rice ... -
Enzyme-based antiviral potential of cinnamomum verum j. presl. essential oil and ıts major component (e)-cinnamaldehyde
(2024)In the present study, Cinnamomum verum J. Presl. bark essential oil and its main component cinnamaldehyde was evaluated in vitro for neuraminidase (NA), transmembrane serine protease (TMPRSS2), and angiotensin converting ... -
Novel microemulsion containing benzocaine and fusidic acid simultaneously: Formulation, characterization, and in vitro evaluation for wound healing
(Springer Science and Business Media Deutschland GmbH, 2024)Modern drug carrier technologies, such as microemulsions with small droplet sizes and high surface areas, improve the ability of low water solubility active ingredients to permeate and localize. The goal of this study was ... -
Development and evaluation of azelaic acid-cyclodextrin hydrogels for treatment of acne
(Marmara University, 2024)Acne is an inflammatory or non-inflammatory disease that can be seen at every stage of human life and affects daily life both physically and psychologically. In the topical treatment of acne, substances with different ... -
Synthesis of new imidazo[1,2-a]pyridine triazole hybrid molecules as potential apoptotic antitumor agents
(John Wiley and Sons Inc, 2024)Novel imidazo[1,2-a]pyridines bearing 1,2,3-triazole moieties at the C3 position were synthesized. After the characterization of the synthesized compounds, their in vitro therapeutic activities were evaluated in various ... -
Determination of aflatoxins and ochratoxin a levels in nuts and dried fruits in Turkey with evaluation of the estimated daily intake
(VUP Food Research Institute, 2023)A total of 140 samples, including nuts and dried fruits sold in the province of Istanbul, Turkey, were examined for the presence of aflatoxins and ochratoxin A (OTA) by high-performance liquid chromatography (HPLC), which ... -
Separate and mutual effects of BIRB796 and bortezomib on pHsp27 and viability of U87MG glioma cells
(Pleiades Publishing, 2023)Hsp27 phosphorylation is associated with many pathways in glioma, such as tumor cell proliferation and apoptosis inhibition. The aim of this study is to examine the separate and mutual effects of BIRB796 and bortezomib on ... -
Phytochemical screening, biological evaluation, anatomical, and morphological investigation of Ferula tingitana L. (Apiaceae)
(Springer Wien, 2023)Ferula tingitana L. is a high perennial plant and its leaf is an alternate arrangement and yellow, and its flowers are unisexual like other Apiaceae. It has been used as a spice and for various medicinal purposes in the ... -
In vitro anti-inflammatory activities of Tanacetum parthenium L. extract and its major metabolite parthenolide
(Istanbul Medipol University, 2024)Tanacetum parthenium L. (Feverfew) is daisy-like Asteraceae plant carrying sesquiterpene lactones; used for the treatment of migraine and anti-inflamma-tory effect. This study aims to evaluate T. parthenium extract and ... -
Phytochemical profile and antioxidant activity potential of Lotus sanguineus (Vural) D.D.Sokoloff
(Istanbul Medipol University, 2024)The in vitro antioxidant activity and phenol, phenolic acid, flavonoid, and proanthocyanidin content of Lotus sanguineus (Vural) D.D.Sokolof extracts were investigated. The aerial parts of Lotus sanguineus have high ... -
The effect of decolonization-decontamination prophylaxis versus traditional prophylaxis in orthopedic surgery in Kosovo
(Istanbul Medipol University, 2024)This study aimed to compare empirical prophylactic treatment with decoloni-zation-decontamination prophylaxis protocol in order to reduce surgical site infections. The study was conducted in Kosovo Ortomedica Orthopedic ... -
In vitro anti-inflammatory and anticancer evaluation of mentha spicata l. and matricaria chamomilla l. essential oils
(American Chemical Society, 2023)Spearmint, Mentha spicata L., and the German chamomile, Matricaria chamomilla L., preparations are used against inflammatory conditions traditionally and in modern medicinal applications. This present study aimed to evaluate ... -
Multiple online-HPLC methodologies and biological properties of leaves and stem barks extracts of Chrysanthellum indicum
(Elsevier Inc., 2024)Chrysanthellum indicum, an annual herb with yellow flowers, is used as a functional food in Asia and Africa for health purposes. In this study, we thoroughly investigated the characterization of phytochemicals within C. ... -
Anatomical, morphological, and chemical characterizations and biological activities of gagea taurica steven (Liliaceae): A new record for the Turkish Flora
(Wiley, 2023)Gagea genus, which is native to the Mediterranean and Black Sea regions, has attracted significant attention due to its biodiversity and potential health benefits. In this study, the biochemical composition and biological ... -
Coumarins from the Dichloromethane Root Extract of Heptaptera triquetra and Their Cytotoxic Activities
(ACG Publications, 2023)A known dihydrofuranocoumarin ester; deltoin (1), together with five known sesquiterpene coumarin ethers; umbelliprenin (2), farnesyl scopoletin (3), karatavicinol (4), colladonin (5), colladin (6), and a novel sesquiterpene ... -
Online-HPLC strategies, antioxidant and enzyme inhibitory activities of different extracts of mondia whitei leaves
(Biolife Sas, 2023)Background: Mondia whitei, an indigenous African plant, is widely recognised for its medicinal properties. Throughout ancient times, African communities have employed this remedy to address a wide range of health conditions. ... -
Evaluation of the effect of honey-containing chitosan/hyaluronic acid hydrogels on wound healing
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)The 3D polymeric network structure of hydrogels imitates the extracellular matrix, thereby facilitating cell growth and differentiation. In the current study, chitosan/hyaluronic acid/honey coacervate hydrogels were produced ... -
Development of light and pH-dual responsive self-quenching theranostic SPION to make EGFR overexpressing micro tumors glow and destroy
(Elsevier B.V., 2023)Drug resistant and undetectable tumors easily escape treatment leading metastases and/or recurrence of the lethal disease. Therefore, it is vital to diagnose and destroy micro tumors using simple yet novel approaches. Here, ... -
The effect of granulocyte colony stimulating factor on genotoxicity in allogeneic peripheral blood stem cell transplantation donors: A prospective case-control study
(Turkish National Pediatric Society, 2023)Background. Every year, thousands of donors are exposed to granulocyte-colony stimulating factor (G-CSF) for stem cell mobilization in hematopoietic stem cell transplantations (HSCT). Previous studies about the genotoxicity ...