Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens

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dc.authorid0000-0001-5605-6159
dc.contributor.authorHoş, Ayşegül
dc.contributor.authorOmurtag Özgen, Pınar Sinem
dc.contributor.authorİnci, Ayşe
dc.contributor.authorAvcı, Buse
dc.contributor.authorCeylan, Ceyda
dc.date.accessioned2023-08-14T09:33:45Z
dc.date.available2023-08-14T09:33:45Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü, Farmasötik Mikrobiyoloji Ana Bilim Dalı
dc.description.abstractThe present study investigated the antibacterial activity of carvacrol against Vancomycin-Resistant Enterococci (VRE), Carbapenem-Resistant Enterobacteriaceae (CRE), Methicillin-Resistant Staphylococcus aureus (MRSA), Escherichia coli ATCC 8739, Enterococcus faecalis ATCC 29212, Streptococcus mitis, Streptococcus mutans CNCTC 8/77 and Streptococcus salivarius CNCTC 64/59. According to the results of the disc diffusion method, carvacrol has extremely high antibacterial activity with zones of 28 mm, 38 mm, 39 mm, 36 mm, 50 mm, 41 mm, 47 mm, and 39 mm against E. coli, E. faecalis, VRE, CRE, S. salivarius, S. mutans, MRSA, S. mitis, respectively. In the present study, the Minimum Inhibition Concentration (MIC) was also investigated by using the Broth Microdilution method. Carvacrol has MIC of 7.62 mg/mL against E. coli, 15.25 mg/mL against VRE, 30.5 mg/mL against E. faecalis, CRE, and S. salivarius, 61 mg/mL against S. mutans, 1.90 mg/mL against MRSA and S. mitis. Carvacrol is a very strong antimicrobial agent and may be used in important applications in the food and pharmaceutical industry. It may also be a good candidate for developing alternative treatments. The results of the present study may be beneficial for further studies with this antibacterial agent for both academia and industry.
dc.identifier.citationHoş, A., Omurtag Özgen, P. S., İnci, A., Avcı, B. ve Ceylan, C. (2023). Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens. Journal of Research in Pharmacy, 27(4), 1380-1387. https://dx.doi.org/10.29228/jrp.425
dc.identifier.doi10.29228/jrp.425
dc.identifier.endpage1387
dc.identifier.issn2630-6344
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85165941966
dc.identifier.scopusqualityQ3
dc.identifier.startpage1380
dc.identifier.trdizinid1189986
dc.identifier.urihttps://dx.doi.org/10.29228/jrp.425
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11314
dc.identifier.volume27
dc.identifier.wos001037386700007en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorHoş, Ayşegül
dc.institutionauthorİnci, Ayşe
dc.institutionauthorAvcı, Buse
dc.institutionauthorCeylan, Ceyda
dc.language.isoen
dc.publisherMarmara University
dc.relation.ispartofJournal of Research in Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/120Z763
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntibacterial Activity
dc.subjectAntibiotic Resistant Bacteria
dc.subjectCarvacrol
dc.subjectEnteric Bacteria
dc.subjectOral Pathogens
dc.titleAntibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens
dc.typeArticle

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