İstanbul Medipol Üniversitesi Kurumsal Akademik Arşivi
DSpace@Medipol, İstanbul Medipol Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
A novel physical layer secret key generation method for wireless sensor networks
(2024) Aygül, Mehmet Ali; Çırpan, Hakan Ali; Arslan, Hüseyin
Wireless sensor networks are indispensable across various applications, from environmental surveillance to indus-trial automation, owing to their ability to collect and transmit data autonomously. However, due to the broadcast nature of wireless systems, these systems are vulnerable to eavesdropping attacks. Recently, channel-based secret key generation methods have been widely used in the literature. In these methods, Alice and Bob generate random signals and share these signals with each other. Then, using the secret key paired multiplication with the channel between them, a secret key is shared between legitimate users, while illegitimate nodes cannot access the key. However, these methods consider only two users. This paper proposes a novel method for multiple users. Extensive simulation proves the effectiveness of the proposed method. However, when the number of users increases, the performance of the proposed method decreases.
The comparison of diabetes management and follow-up by family medicine or endocrinology
(2024) Arman, İkbal Hümay; Arman, Yusuf; Ayaz, Zeynep; Bahadır, Ahmet Emre; Apaydın Kaya, Memnune Çiğdem
Objectives: This study aimed to compare the disease management of type 2 diabetes mellitus (T2DM) patients followed up in family medicine (FM) or endocrinology outpatient clinics. Methods: This descriptive study was carried out with T2DM patients who applied to endocrinology and FM outpatient clinics. When analyzing data, patients who only went to endocrinologists (Group 1) and patients who went to both endocrinology and FM or only FM (Group 2) were compared. A questionnaire form (sociodemographic characteristics, education, disease management status, and hemoglobin A1c [HbA1c] levels) was applied to participants. Results: A total of 151 participants were enrolled in the study, with 49 (32.5%) in Group 1 and 102 (67.5%) in Group 2. The median value of HbA1c was 7.5% (2.1%) in Group 1 and 7.1% (2.2%) in Group 2 (p=0.324). Blood glucose measurement abilities and the ability to adjust the insulin dose were higher in Group 1 (47 [95.9%] vs. 75 [73.5%], p=0.001; 22 [44.9%] vs. 15 [14.7%], p<0.001, respectively). However, the frequency of blood pressure measurement, foot examination, and neurological examination was higher in Group 2 (17 [34.7%] vs. 64 [62.7%], p=0.001 for blood pressure measurement; 3 [6.1%] vs. 26 [25.5%], p=0.005 for the foot examination; and 2 [4.1%] vs. 24 [23.5%], p=0.003 for the neurological examination, respectively). Conclusion: While no difference was found in HbA1c levels according to the clinics where the patients were followed, it is noteworthy that blood pressure measurements and foot and neurological examinations were performed more frequently in patients visiting their FMs.
The typology of well-being and imagination on global organization leaders and the wisdom of classical period philosophers
(2024) Acar, Pınar; Güngörmez Şeker, Dilek; Yeke, Müge
The understanding of well-being and imagination reflected from classical period philosophers to the present day is now the focus of today’s leaders and managers. In the modern management concept there is a continuous constructive and reformative process. While organizations concentrate on organizational subjects such as work/life balance, the positive culture of the organization, emotional welfare, happiness and ideal working environment, there is also a need to reach a stage of awareness for an integrated understanding and responsibility on social equality, social responsibility, ecological order and biodiversity. The aim of our research is to discover how the wisdom and teachings of classical period philosophers are reflected by today’s global organization leaders. In our research, interviews and statements of the leaders of Fortune 500 listed, global companies such as Samsung, Apple, UPS, Airbus, Amazon, Johnson& Johnson and Walmart were collected and used as secondary data. The data analysis was done using Nvivo (version 2020). The results showed that leaders of global organizations adopted the teachings on well-being and imagination of classical period philosophers such as Plato, Aristotle and Socrates and carried the dimensions such as leader’s well-being, imagination, hedonic approach, subjective well-being, emotional well-being (happiness), positive affection, negative affection, cognitive well-being, life satisfaction, eudaimonic approach and psychological well-being.
Prognostic significance of the advanced lung cancer inflammation index in metastatic small cell lung cancer: a retrospective analysis of 96 patients
(2024) Ürün, Müslih; Güner, Gürkan; Sezgin, Yasin; Uysal, Emre; Sakin, Abdullah; Kılıçkap, Saadettin
Background: The advanced lung cancer inflammation index (ALI) is regarded as a potential indicator of systemic inflammation. This retrospective study aimed to evaluate the prognostic role of the ALI in 96 patients with advanced small cell lung cancer (SCLC). Material/Methods: This retrospective study included 96 patients who were diagnosed with extensive stage SCLC in a single institution between 2016 and 2022. The formula for ALI is body mass index (kg/m2)×serum albumin (g/dL)/neutrophil to lymphocyte ratio. Patients were divided into low inflammation (ALI ≥32.5) and high inflammation (ALI <32.5) groups. Kaplan-Meier analysis and Cox proportional analysis were conducted to assess the association between the ALI and patient prognosis. Results: Median age was 61 (range: 41-82) years. Median follow-up was 9 months, and median overall survival (OS) was 10 months (95% CI: 7.75-12.45). A lower ALI score (ALI <32.5) was correlated with a poorer OS than was a higher ALI score (median OS 7 months for ALI <32.5 95% CI: 4.6-9.3 vs 15 months for ALI ≥32.5, 95% CI: 10.6-19.3, P<0.001). In the multivariate analysis, ALI score, Eastern Cooperative Oncology Group performance status, brain metastasis, and bone metastasis were identified as independent prognostic factors. Conclusions: ALI score is a substantial predictor of survival in SCLC as in other types of cancer types. Patients with a low ALI score have poorer survival. Assessment of ALI can identify lung cancer patients at high risk of poor prognosis and can be a useful prognostic marker in clinical practice.
Percutaneous nephrostomy in infants: a 20-year single-center experience
(2024) Taydaş, Onur; Ünal, Emre; Akıncı, Devrim; Şeker, Mehmet; Topçuoğlu, Osman Melih; Akhan, Okan; Çiftçi, Türkmen Turan
PURPOSE To investigate the safety and efficacy of the imaging-guided percutaneous nephrostomy (PCN) procedure in infants. METHODS A total of 75 (50 boys; 66.7%) patients with a mean age of 121 days (range, 1–351 days) who underwent PCN over a period of 20 years were included in this retrospective study. For each patient, PCN indications, catheter size, the mean duration of catheterization, complications, and the procedure performed following nephrostomy were recorded. Technical success was determined based on the successful placement of the nephrostomy catheter within the pelvicalyceal system. Clinical success was defined as the complete resolution of hydronephrosis and improvement in renal function tests during follow-up. In patients with urinary leakage, technical and clinical success was determined based on the resolution of leakage. RESULTS The technical success rate was 100%, and no procedure-related mortality was observed. In 11 patients (14.7%), bilateral PCN was performed. The most frequent indication of PCN was ureteropelvic junction obstruction (n = 41, 54.7%). Procedure-related major complications were encountered in two patients (methemoglobinemia and respiratory arrest caused by the local anesthetic agent in one patient and the development of urinoma caused by urinary leakage from the puncture site in the other). Mild urinary leakage was the only minor complication that occurred and only in one patient. Catheter-related complications were managed through replacement or revision surgery in 16 patients (21.3%). CONCLUSION Imaging-guided PCN is a feasible and effective procedure with high technical success and low major complication rates, and it is useful for protecting kidney function in infants.
