Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica

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dc.authorid0000-0003-2533-5141
dc.contributor.authorTosun, Fatma
dc.contributor.authorAytar, Erdi Can
dc.contributor.authorBeutler, John A.
dc.contributor.authorWilson, Jennifer A.
dc.contributor.authorMiski, Mahmut
dc.date.accessioned2021-06-17T06:56:07Z
dc.date.available2021-06-17T06:56:07Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalı
dc.description.abstractPreliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent and selective cytotoxic activities were isolated from the dichloromethane extract of the roots of H. cilicica. Furthermore, revised spectroscopic data for 14'-acetoxybadrakemone (4) and complete NMR spectroscopic assignments for colladonin (6) and colladin (7) are reported.
dc.identifier.citationTosun, F., Aytar, E. C., Beutler, J. A., Wilson, J. A. ve Miski, M. (2021). Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica. Records of Natural Products, 15(6), 529-536. https://dx.doi.org/10.25135/rnp.242.21.02.1990
dc.identifier.doi10.25135/rnp.242.21.02.1990
dc.identifier.endpage536
dc.identifier.issn1307-6167
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage529
dc.identifier.urihttps://dx.doi.org/10.25135/rnp.242.21.02.1990
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7205
dc.identifier.volume15
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherACG Publications
dc.relation.ispartofRecords of Natural Productsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHeptaptera Cilicica
dc.subjectApiaceae
dc.subjectSesquiterpene Coumarins
dc.subjectCytotoxic Activity
dc.titleCytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica
dc.typeArticle

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