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Toplam kayıt 171, listelenen: 131-140
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: A randomised, double-blinded, placebo-controlled phase-II trial
(BioMed Central Ltd, 2023)
Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed ...
Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
(Comenius University, 2021)
OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis
powder extract (CEPE) formulation on incisional and excisional wounds in rat.
BACKGROUND: In the event of any damage, ...
A two-stage diagnosis strategy for COVID-19 and similar pandemics
(Türkiye Klinikleri, 2021)
Objective: Coronavirus disease-2019 (COVID-19) outbreak emerged in Wuhan-China in December-2019, and has covered the world by rapidly becoming a pandemic, infecting >4.5 million by mid-May 2020, killing >300,000 globally, ...
The role of circadian rhythm in the regulation of cellular protein profiles in the brain
(The Scientific and Technological Research Council of Turkey, 2021)
Background/aim: Circadian rhythm plays a significant role in the regulation of almost all kinds of physiological processes. In addition, it may also have a direct or indirect effect on the neurodegenerative processes, ...
Effects of cichorium intybus on GABA(A) receptors and apoptosis in pentylenetetrazole-induced kindling in rats
(Kare Publishing, 2021)
Objectives: This study was designed to determine the effects of Cichorium intybus (CI) on apoptosis and GABA(A) receptor density in the brains of rats in pentyleneterazole induced kindling.
Methods: The rats were divided ...
Combined segmentation and classificationbased approach to automated analysis of biomedical signals obtained from calcium imaging
(Public Library of Science, 2023)
Automated screening systems in conjunction with machine learning-based methods are becoming an essential part of the healthcare systems for assisting in disease diagnosis. Moreover, manually annotating data and hand-crafting ...
Classification of Parkinson's disease with dementia using phase locking factor of event-related oscillations to visual and auditory stimuli
(IOP Publishing Ltd, 2023)
Objective. In the last decades, machine learning approaches have been widely used to distinguish Parkinson’s disease (PD) and many other neuropsychiatric diseases. They also speed up the clinicians and facilitate decision-making ...
Depression affects working memory performance: A Functional Near Infrared Spectroscopy (fNIRS) Study
(Elsevier Ireland Ltd, 2023)
Depression is a complex disorder that can be caused by psychosocial and biological conditions, and it not only affects to emotional life, but also cognitive functions, specifically the executive functions, attention, ...
A proteomic analysis for profiling NeuroD2 related changes in N2A neuroblastoma cell line
(Inönü University Faculty of Medicine, 2023)
Aim: NeuroD2 transcription factor is a key regulator of neurogenin-NeuroD signaling network and induces neuronal development, differentiation, neurogenesis and calcium de- pendent signaling. NeuroD2 regulates expression ...
Development of a chemogenetic approach to manipulate intracellular pH
(American Chemical Society, 2023)
Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ...