• Far-infrared treatment of experimental sinusitis in rabbits: A pilot study 

  Ceylan, S.; Özdemir, Hüseyin; Aydın, Mehmet Şerif (Verduci Publisher, 2023)

  OBJECTIVE: Thermal therapy has existed for thousands of years and dates back to ancient civilizations such as the Finns, Romans, ancient Chinese, American Indians, and Egyptians. Sun therapy is a form of natural Far Infrared ...

• Comparison of the efficiencies of intrathecal and intraganglionic injections in mouse dorsal root ganglion 

  Aydın, Mehmet Şerif; Yiğit, Esra Nur (Turkiye Klinikleri, 2023)

  Background/aim: Dorsal root ganglia (DRG) are structures containing primary sensory neurons. Intraganglionic (IG) and intrathecal (IT) applications are the most common methods used for viral vector transfer to DRG. We aim ...

• Morphology-dependent immunomodulatory coating of hydroxyapatite/PEO for magnesium-based bone implants 

  Farshid, Safoura; Kharaziha, Mahshid; Salehi, Hossein; Ganjalikhani Hakemi, Mazdak (2023)

  One of the most critical issues concerning orthopedic implants is the risk of chronic inflammation, which poses a threat to the bone healing process. Osteo-immunomodulation plays a pivotal role in implant technology by ...

• TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice 

  Sürme, Saliha; Ergün, Çağla; Gül, Şeref; Akyel, Yasemin Kübra; Gül, Zeynep Melis; Özcan, Onur; Şavluğ İpek, Özgecan; Akarlar, Büşra Aytül; Özlü, Nurhan; Taşkın, Ali Cihan; Türkay, Metin; Gören, Ahmet Ceyhan; Barış, İbrahim; Öztürk, Nuri; Güzel, Mustafa; Aydın, Cihan; Okyar, Alper; Kavaklı, İbrahim Halil (Elsevier Inc., 2023)

  Cryptochromes (CRYs), transcriptional repressors of the circadian clock in mammals, inhibit cAMP production when glucagon activates G-protein coupled receptors. Therefore, molecules that modulate CRYs have the potential ...

• Evaluating the clinical significance of diazepam binding inhibitor in alzheimer's disease: A comparison with inflammatory, oxidative, and neurodegenerative biomarkers 

  Gökçe, Mustafa; Velioğlu, Halil Aziz; Bektay, Muhammed Yunus; Güler, Eray Metin (Karger, 2023)

  Introduction: Alzheimer's disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor for ...

• Blood viscosity and inflammation in first-episode and acute exacerbations of schizophrenia: A case-control study with healthy controls 

  Balcıoğlu, Yasin Hasan; Gökçay, Hasan; Yeşilkaya, Ümit Haluk; Namlı, Mustafa Nuray (Turkish Neuropsychiatric Society, 2023)

  Introduction: Elevated proinflammatory status and alterations in blood flow, both of which are associated with the pathophysiology of schizophrenia, may be linked with an increased risk of cardiovascular diseases. However, ...

• Investigating the effects of glucose and lipid metabolism on neuronal structure using optical coherence tomography in treatment-resistant schizophrenia 

  Yeşilkaya, Ümit Haluk; Şahmelikoğlu Onur, Özge; Akarsu Acar, Özge Pınar; Göy, Defne Flora; Onur, İsmail Umut; Karamustafalıoğlu, Nesrin (Kare Publishing, 2023)

  Objective:The effects of metabolic changes on neural structures in the later stages of schizophrenia remain unknown. Alterations in glucose and lipid metabolism could impact disease progression. This study aims to investigate ...

• The IL-25/ILC2 axis promotes lung cancer with a concomitant accumulation of immune-suppressive cells in tumors in humans and mice 

  Bahhar, İlham; Eş, Zeynep; Köse, Oğuzhan; Turna, Akif; Günlüoğlu, Mehmet Zeki; Çakır, Aslı; Duralı, Deniz; Magnusson, Fay C. (Frontiers Media SA, 2023)

  Background: Group 2 innate lymphoid cells (ILC2) can be activated by interleukin (IL)-33 or IL-25. IL-25-activated ILC2 cells help protect the host against helminth infection while exacerbating allergic-like inflammation ...

• High-resolution mapping of sensory fibers at the healthy and post-myocardial infarct whole transgenic hearts 

  Göktaş Şahoğlu, Sevilay; Kazcı, Yusuf Enes; Karadoğan, Behnaz; Aydın, Mehmet Şerif; Nebol, Aylin; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Wiley, 2023)

  The sensory nervous system is critical to maintain cardiac function. As opposed to efferent innervation, less is known about cardiac afferents. For this, we mapped the VGLUT2-expressing cardiac afferent fibers of spinal ...

• A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients 

  Velioğlu, Halil Aziz; Ayyıldız, Behçet; Ayyıldız, Sevilay; Sütçübaşı, Bernis; Hanoğlu, Lütfü; Bayraktaroğlu, Zübeyir; Yuluğ, Burak (John Wiley and Sons Inc, 2023)

  In Alzheimer's disease (AD), structural and functional changes in the brain may give rise to disruption of specific cognitive functions. The aim of this study is to investigate the functional connectivity alterations in ...

• Helper innate lymphoid cells as cell therapy for cancer 

  Magnusson, Fay Celeste; Bahhar, Ilham (Wiley, 2023)

  Although the first cancer immunotherapy was given in the clinic more than a century ago, this line of treatment has remained more of a distant goal than a practical therapy due to limited understanding of the tumour ...

• Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease 

  Ayyıldız, Sevilay; Velioğlu, Halil Aziz; Ayyıldız, Behçet; Sütçübaşı, Bernis; Hanoğlu, Lütfü; Bayraktaroğlu, Zübeyir; Yıldırım, Süleyman; Atasever, Alper; Yuluğ, Burak (Wiley, 2023)

  The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ...

• Active shrinkage protects neurons following axonal transection 

  Aydın, Mehmet Şerif; Bay, Sadık; Yiğit, Esra Nur; Özgül, Cemil; Kaval Oğuz, Elif; Yenidünya Konuk, Elçin; Ayşit, Neşe; Cengiz, Nureddin; Erdoğan, Ender; Him, Aydın; Koçak, Mehmet; Eroğlu, Emrah; Öztürk, Gürkan (Elsevier Inc., 2023)

  Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ...

• The effects of transcranial focused ultrasound stimulation of nucleus accumbens on neuronal gene expression and brain tissue in high alcohol-preferring rats 

  Deveci, Erdem; Akbaş, Fahri; Ergün, Arif Şanlı; Kurtulmuş, Ayşe; Koçak, Ali Barlas; Boyraz, Rabia Kevser; Tok, Olgu Enis; Aydın, Mehmet Şerif; Kılıç, Özge; Bozkurt, Ayhan; Uysal, Ömer; Eşrefoğlu, Mukaddes (Springer, 2023)

  We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histological effects on brain tissue. We also aimed at determining the miRNA-mRNA relationship and ...

• The unconventional growth factors cerebral dopamine neurotrophic factor and mesencephalic astrocyte-derived neurotrophic factor promote post-ischemic neurological recovery, perilesional brain remodeling, and lesion-remote axonal plasticity 

  Çağlayan, Ahmet Burak; Beker, Mustafa Çağlar; Sertel Evren, Elif; Çağlayan, Berrak; Kılıç, Ülkan; Ateş, Nilay; Çağlayan, Aysun; Daşdelen, Muhammed Furkan; Doeppner, Thorsten Roland; Saarma, Mart; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Springer, 2023)

  Considerable efforts are currently made to develop strategies that boost endogenous recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic factors are attractive candidates that capitalize ...

• Türkiye popülasyonunda HLA-DQ polimorfizmlerinin Hepatit B virüs enfeksiyonu ile ilişkisi 

  Çakal, Bülent; Arıkan, Muzaffer; Atasoy, Alp; Çavuş, Bilger; Poda, Mehveş; Bulakçı, Mesut; Güllüoğlu, Mine; Demirci, Mehmet; Akyüz, Filiz (İstanbul Üniversitesi, 2022)

  Amaç Konak genetik faktörleri hepatit B virüs (HBV) enfeksiyonunun doğal seyri ve HBV ilişkili karaciğer hastalıklarının gelişme riski ile progresyonu üzerinde etkili olabilmektedir. Bu çalışmada HLA-DQ gen rs9272105, ...

• Blood viscosity and inflammatory indices in treatment-resistant schizophrenia: A retrospective cross-sectional study 

  Balcıoğlu, Yasin Hasan; Gökçay, Hasan; Yeşilkaya, Ümit Haluk; Kirlioğlu Balcıoğlu, Simge Seren (Kare Publishing, 2023)

  Objective: Alterations in blood flow and inflammation may be associated with the treatment response of psychotic disorders. However, changes in blood viscosity in patients with treatment-resistant schizophrenia (TRS) have ...

• The impact of COVID-19 on patients with chronic obstructive pulmonary disease 

  Bener, Abdulbari; Kök, Kıvanç; Naser, Abdulrahman; Barışık, Cem Cahit; Nurkalem, Zekeriya (Edizioni Minerva Medica, 2023)

  BACKGROUND: The aim of this study was to evaluate the risk of serious adverse outcomes in patients with chronic obstructive pulmonary disease (COPD) related to COVID-19 by stratifying the comorbidity status.METHODS: This ...

• Development of a chemogenetic approach to manipulate intracellular pH 

  Zaki, Asal Ghaffari; Miri, Seyed Mohammad; Çimen, Şeyma; Akgül Çağlar, Tuba; Yiğit, Esra Nur; Aydın, Mehmet S.; Öztürk, Gürkan; Eroğlu, Emrah (American Chemical Society, 2023)

  Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ...

• Downregulation of Yap1 during limb regeneration results in defective bone formation in axolotl 

  Bay, Sadık; Öztürk, Gürkan; Emekli, Nesrin; Demircan, Turan (Elsevier Inc., 2023)

  The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ growth, apoptosis, and cell cycle. Transcription coregulator component of Hippo pathway, YAP1, ...

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