Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 295, listelenen: 273-292
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TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines
(Frontiers Media SA, 2023)Introduction: T-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell ... -
TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1
(BioMed Central Ltd, 2024)Background: T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid ... -
Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3
(Springer/Plenum Publishers, 2016)Hypoxic-ischemia (HI) is a widely used animal model to mimic the preterm or perinatal sublethal hypoxia, including hypoxic-ischemic encephalopathy. It causes diffuse neurodegeneration in the brain and results in mental ... -
Time irreversibility of resting-state activity in the healthy brain and pathology
(Frontiers Media S.A., 2020)Characterizing brain activity at rest is of paramount importance to our understanding both of general principles of brain functioning and of the way brain dynamics is affected in the presence of neurological or psychiatric ... -
Time-of-day dependent neuronal injury after ischemic stroke: Implication of circadian clock transcriptional factor bmal1 and survival kinase akt
(Humana Press Inc, 2018)Occurrence of stroke cases displays a time-of-day variation in human. However, the mechanism linking circadian rhythm to the internal response mechanisms against pathophysiological events after ischemic stroke remained ... -
Topological network mechanisms of clinical response to antidepressant treatment in drug-naive major depressive disorder
(Elsevier Ltd, 2021)Aim: There is rapidly increasing evidence that remission of MDD is associated with substantial changes in functional brain connectivity. These New data have provided a holistic view on the mechanism of antidepressants on ... -
Transfer and integration of breast milk stem cells to the brain of suckling pups
(Nature Publishing Group, 2018)Beside its unique nutritional content breast milk also contains live cells from the mother. Fate of these cells in the offspring has not been adequately described. In this study, we aimed to detect and identify maternal ... -
Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease
(Elsevier B.V., 2022)Alzheimer's disease dementia (ADD) is the most diffuse neurodegenerative disorder belonging to mild cognitive impairment (MCI) and dementia in old persons. This disease is provoked by an abnormal accumulation of amyloid-beta ... -
Türkiye popülasyonunda HLA-DQ polimorfizmlerinin Hepatit B virüs enfeksiyonu ile ilişkisi
(İstanbul Üniversitesi, 2022)Amaç Konak genetik faktörleri hepatit B virüs (HBV) enfeksiyonunun doğal seyri ve HBV ilişkili karaciğer hastalıklarının gelişme riski ile progresyonu üzerinde etkili olabilmektedir. Bu çalışmada HLA-DQ gen rs9272105, ... -
TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice
(Elsevier Inc., 2023)Cryptochromes (CRYs), transcriptional repressors of the circadian clock in mammals, inhibit cAMP production when glucagon activates G-protein coupled receptors. Therefore, molecules that modulate CRYs have the potential ... -
Two boron-containing compounds affect the cellular viability of SH-SY5Y cells in an in vitro amyloid-beta toxicity model
(Scientific and Technological Research Council of Turkey (TÜBİTAK), 2020)Boron is a naturally occurring trace element found in organic and inorganic complexes. Boron-containing compounds are required for living organisms for diverse metabolic functions, including nitrogen fixation in microorganisms, ... -
Two phases of macrophages: Inducing maturation and death of oligodendrocytes in vitro co-culture
(Elsevier B.V., 2022)Background: The plasticity of macrophages in the immune response is a dynamic situation dependent on external stimuli. The activation of macrophages both has beneficial and detrimental effects on mature oligodendrocytes ... -
A two-stage diagnosis strategy for COVID-19 and similar pandemics
(Türkiye Klinikleri, 2021)Objective: Coronavirus disease-2019 (COVID-19) outbreak emerged in Wuhan-China in December-2019, and has covered the world by rapidly becoming a pandemic, infecting >4.5 million by mid-May 2020, killing >300,000 globally, ... -
The unconventional growth factors cerebral dopamine neurotrophic factor and mesencephalic astrocyte-derived neurotrophic factor promote post-ischemic neurological recovery, perilesional brain remodeling, and lesion-remote axonal plasticity
(Springer, 2023)Considerable efforts are currently made to develop strategies that boost endogenous recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic factors are attractive candidates that capitalize ... -
Urinary microbiome in uncomplicated and interstitial cystitis: Is there any similarity?
(Springer, 2020)Purpose Acute/uncomplicated cystitis is the most common bacterial infection causing inflammation in the bladder tissues and predominantly diagnosed in women. Interstitial cystitis may too, cause inflammation in the bladder ... -
The use of platelet-rich plasma for storage of surplus harvested skin grafts
(Sage Publications Inc, 2017)Background:There is a need for improved methods and storage media to sustain the tissue viability of autologous skin grafts.Objective:To compare histological changes in human skin grafts stored in platelet-rich plasma (PRP) ... -
Üstün zekâlı çocukların annelerinin gebelik sürecindeki beslenme alışkanlıklarının saptanması: Retrospektif bir çalışma
(Türkiye Klinikleri, 2023)Amaç: Bu araştırmada, üstün zekâlı çocuğu olan annelerin gebelik dönemindeki beslenme al ışkanlıklarının araştırılması ve kontrol grubu ile karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Retrospektif ve ta- nımlayıcı ... -
Verteporfin mediated sequence dependent combination therapy against ovarian cancer cell line
(Elsevier Science Sa, 2018)Ovarian Cancer is one of the deadliest gynecological cancer showing high resistance to chemotherapy. Non overlapping and synergistic combination therapies are the best option to overcome this multi-pathological silent ... -
What a single electroencephalographic (EEG) channel can tell us about alzheimer's disease patients with mild cognitive impairment
(NLM (Medline), 2023)Abnormalities in cortical sources of resting-state eyes closed electroencephalographic (rsEEG) rhythms recorded by hospital settings (10-20 montage) with 19 scalp electrodes characterized Alzheimer's disease (AD) from ... -
Wound healing effects of methanol extract of Laurocerasus officinalis roem
(Taylor & Francis Ltd, 2019)Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using ...
