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Toplam kayıt 11, listelenen: 1-10
Proteomic analysis of kidney preservation solutions prior to renal transplantation
(Public Library Science, 2016)
One of the main issues in kidney transplantation is the optimal functional preservation of the organ until its transplantation into the appropriate recipient. Despite intensive efforts, the functional preservation period ...
Mutant SOD1 protein increases Na(v)1.3 channel excitability
(Springer, 2016)
Amyotrophic lateral sclerosis (ALS) is a lethal paralytic disease caused by the degeneration of motor neurons in the spinal cord, brain stem, and motor cortex. Mutations in the gene encoding copper/zinc superoxide dismutase ...
Systemic proteasome inhibition induces sustained post-stroke neurological recovery and neuroprotection via mechanisms involving reversal of peripheral immunosuppression and preservation of blood-brain-barrier integrity
(Springer, 2016)
In view of its profound effect on cell survival and function, the modulation of the ubiquitin-proteasome-system has recently been shown to promote neurological recovery and brain remodeling after focal cerebral ischemia. ...
Recombinant plasmid-based quantitative Real-Time PCR analysis of salmonella enterica serotypes and its application to milk samples
(Elsevier Science Bv, 2016)
The aim of the current study was to develop, a new, rapid, sensitive and quantitative Salmonella detection method using a Real-Time PCR technique based on an inexpensive, easy to produce, convenient and standardized ...
Comprehensive screening of eight known causative genes in congenital hypothyroidism with gland-in-situ
(Endocrine Society, 2016)
Context: Lower TSH screening cutoffs have doubled the ascertainment of congenital hypothyroidism (CH), particularly cases with a eutopically located gland-in-situ (GIS). Although mutations in known dyshormonogenesis genes ...
α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
(Springer, 2016)
Multiple system atrophy (MSA) is a rare atypical parkinsonian disorder characterized by a rapidly progressing clinical course and at present without any efficient therapy. Neuropathologically, myelin loss and neurodegeneration ...
The heart of the matter: Cardiac stem cells
(Tubitak Scientific, 2016)
Cardiovascular diseases are the primary cause of death in the world. Pharmacological and surgical approaches are the main treatment options for heart disease; however, heart transplantation may be the only option for ...
Myelin disorders and stem cells: As therapies and models
(Tubitak Scientific & Technical Research Council, 2016)
Myelin disorders burden millions of people around the world, yet existing therapies are inadequate to cure them. Current remedies commonly treat the symptoms with minimal to no effect on the actual cause of the disorder. ...
Erratum to: Mutant SOD1 protein increases Na(v)1.3 channel excitability
(Springer, 2016)
Firing patterns of a mammalian neuron in response to changes in Nav conductance induced by hSOD1A4V. a At the baseline (see Methods), there is no predicted spontaneous firing as modeled using NEURON software (left; resting ...
Axolotl cells and tissues enhances cutaneous wound healing in mice
(2016)
Adult mammalian skin wound repair is defective due to loss of the regulation in balancing the complete epithelial regeneration and excessive connective tissue
production, and this repair process commonly results in scar ...