Yazar "Akgül Çağlar, Tuba" için Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) listeleme
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Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
Koç, Arzuhan; Şahoğlu Göktaş, Sevilay; Akgül Çağlar, Tuba; Çağavi, Esra (Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ... -
Development of a chemogenetic approach to manipulate intracellular pH
Zaki, Asal Ghaffari; Miri, Seyed Mohammad; Çimen, Şeyma; Akgül Çağlar, Tuba; Yiğit, Esra Nur; Aydın, Mehmet S.; Öztürk, Gürkan; Eroğlu, Emrah (American Chemical Society, 2023)Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ... -
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
Akgül Çağlar, Tuba; Durdu, Zeynep Begüm; Turhan, M. U.; Günal, Mehmet Yalçın; Aydın, Mehmet Şerif; Öztürk, Gürkan; Çağavi, Esra (Elsevier, 2021)The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ... -
Experimental data of labeling the heart and cardiac cultures with a retrograde tracer in vitro and in vivo
Akgül Çağlar, Tuba; Günal, Mehmet Yalçın; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Elsevier Inc., 2021)Retrograde dyes are often used in basic research to investigate neuronal innervations of an organ. This article describes the experimental data on the application of retrograde dyes on the mouse heart in vivo and on the ... -
Patient-specific induced pluripotent stem cells for cardiac disease modeling
Çağavi, Esra; Akgül Çağlar, Tuba; Haider, Khawaja Husnain; Söztekin, Gökçe İlayda (Walter de Gruyter GMBH, 2019)Reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) via induction of pluripotency genes is one of the most influential scientific breakthroughs during the last decade. Behind this breakthrough ... -
Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering
Aydemir Sezer, Ümran; Öztürk Yavuz, Kevser; Örs, Gizem; Bay, Sadık; Aru, Başak; Söğüt, Oğuz; Akgül Çağlar, Tuba; Bozkurt, Mehmet Recep; Çağavi, Esra; Yanıkkaya Demirel, Gülderen; Sezer, Serdar; Karaca, Hüseyin (Wiley, 2020)Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral ...