Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 72, listelenen: 21-40
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A novel fontan Y-graft for interrupted inferior vena cava and azygos continuation
(Elsevier Science, 2022)Objectives: To evaluate the hemodynamicdynamic advantage of a new Fontan surgical template that is intended for complex single-ventricle patients with interrupted inferior vena cava-azygos and hemi-azygos continuation. The ... -
In vitro measurement of hepatic flow distribution in Fontan vascular conduits: Towards rapid validation techniques
(Elsevier Ltd, 2022)Fontan operation is the last stage of single-ventricle surgical reconstructions that connects superior and inferior vena cava (SVC, IVC) to the pulmonary arteries. The key design objectives in total cavopulmonary connections ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
(MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ... -
A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task
(Elsevier B.V., 2022)Background: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet. New method: Here, we describe ... -
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ... -
Antileishmanial activity of BNIPdaoct- and BNIPdanon-loaded emulsomes on leishmania infantum parasites
(Frontiers Media S.A., 2022)Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ... -
Investigation into cervical spine biomechanics following single, multilevel and hybrid disc replacement surgery with dynamic cervical implant and fusion: A finite element study
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Cervical fusion has been a standard procedure for treating abnormalities associated with the cervical spine. However, the reliability of anterior cervical discectomy and fusion (ACDF) has become arguable due to its adverse ... -
Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
(Comenius University, 2021)OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis powder extract (CEPE) formulation on incisional and excisional wounds in rat. BACKGROUND: In the event of any damage, ... -
Clinical evaluation of decompressive craniectomy in malignant middle cerebral artery infarction using 3d area and volume calculations
(Wolters Kluwer Medknow Publications, 2021)Objective: We aimed to measure the craniectomy area using three-dimensional (3D) anatomic area and volume calculations to demonstrate that it can be an effective criterion for evaluating survival and functional outcomes ... -
Microwave-promoted continuous flow systems in nanoparticle synthesis-A perspective
(American Chemical Society, 2021)Microwave-promoted continuous flow systems have emerged as a game-changer in nanoparticle synthesis. Owing to the excellent compatibility between fast, sustainable microwave heating and one-step, efficient flow chemistry, ... -
Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei
(Elsevier Science Inc, 2021)The study described here examined the effects of cavitation nuclei characteristics on histotripsy. Highspeed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ... -
Quantitative phase macroscopic system for label-free imaging of tissue sections
(İstanbul University, 2021)Optical microscopes are typically designed as versatile tools that are capable of imaging at various modalities with different resolutions in respective visual fields. A large extend of versatility causes increased complexity, ... -
Computational modeling of vascular growth in patient-specific pulmonary arterial patch reconstructions
(Elsevier Ltd, 2021)Recent progress in vascular growth mechanics has involved the use of computational algorithms to address clinical problems with the use of three-dimensional patient specific geometries. The objective of this study is to ... -
Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model
(Dove Medical Press Ltd, 2020)Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ... -
DU 145 insan prostat kanseri hücrelerinde Hsa-Mir-8072’nin potansiyel rolü
(Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2019)Amaç: Çalışmamızda, insan prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında miRNA ifadesinin analizini yapmak ve kanser gelişiminde olası rolünü incelemeği amaçladık. Gereçler ve ... -
Cytotoxicity of standardized curcuminoids mixture against epithelial ovarian cancer cell line SKOV-3
(MDPI, 2020)Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its therapeutic agents in modern medicine is currently being studied. Curcuminoids are an example of natural agents, ... -
Scattering metal waveguide based speckle-enhanced prism spectrometry
(IEEE - Institute of Electrical and Electronics Engineers, Inc., 2020)We present an optical efficiency improved speckle spectrometer where a scattering metal wave-guide is utilized along with a conventional prism spectrometer. We conducted extensive tests on 25 different scatterers, involving ... -
Proteomic study of hepatocellular carcinoma using a novel modified aptamer-based array (SOMAscan (TM)) platform
(Elsevier Science, 2017)Vascular invasion is a pathological hallmark of hepatocellular carcinoma (HCC), associated With poor prognosis; it is strongly related to the early recurrence and poor survival after curative resection. In order to determine ... -
Curcumin- and Piperine-loaded emulsomes as combinational treatment approach enhance the anticancer activity of Curcumin on HCT116 colorectal cancer model
(Frontiers in Bioengineering and Biotechnology, 2020)Combination chemotherapy, administrating two chemotherapeutic agents concurrently, comes into prominence, as the heterogeneity or the level of the disease necessitates a collaborative action. Curcumin, isolated from turmeric, ... -
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
(MDPI, 2019)Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ...