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Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei
(Elsevier Science Inc, 2021)The study described here examined the effects of cavitation nuclei characteristics on histotripsy. Highspeed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ... -
Computational modeling of vascular growth in patient-specific pulmonary arterial patch reconstructions
(Elsevier Ltd, 2021)Recent progress in vascular growth mechanics has involved the use of computational algorithms to address clinical problems with the use of three-dimensional patient specific geometries. The objective of this study is to ... -
Quantitative phase macroscopic system for label-free imaging of tissue sections
(İstanbul University, 2021)Optical microscopes are typically designed as versatile tools that are capable of imaging at various modalities with different resolutions in respective visual fields. A large extend of versatility causes increased complexity, ... -
Clinical evaluation of decompressive craniectomy in malignant middle cerebral artery infarction using 3d area and volume calculations
(Wolters Kluwer Medknow Publications, 2021)Objective: We aimed to measure the craniectomy area using three-dimensional (3D) anatomic area and volume calculations to demonstrate that it can be an effective criterion for evaluating survival and functional outcomes ... -
Can Carpobrotus edulis, heal incisional and excisional wounds on the skin?
(Comenius University, 2021)OBJECTIVES: This study aimed to investigate the wound healing activity of liposomal Carpobrotus edulis powder extract (CEPE) formulation on incisional and excisional wounds in rat. BACKGROUND: In the event of any damage, ... -
The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions
(Springer Nature, 2022)Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ... -
Biomechanical study on three screw-based atlantoaxial fixation techniques: A finite element study
(Korean Society of Spine Surgery, 2022)Study Design: This is a finite element study. Purpose: This study is aimed to compare the biomechanical behaviors of three screw-based atlantoaxial fixation techniques. Overview of Literature: Screw-based constructs that ... -
Investigation into cervical spine biomechanics following single, multilevel and hybrid disc replacement surgery with dynamic cervical implant and fusion: A finite element study
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Cervical fusion has been a standard procedure for treating abnormalities associated with the cervical spine. However, the reliability of anterior cervical discectomy and fusion (ACDF) has become arguable due to its adverse ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
(MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ... -
Investigation of 3D-printed chitosan-xanthan gum patches
(Elsevier B.V., 2022)In this study, using a new polymer combination of Chitosan(CH)/Xanthan Gum(XG) has been exhibited for wound dressing implementation by the 3D-Printing method, which was fabricated due to its biocompatible, biodegradable, ... -
SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers
(Elsevier B.V., 2022)Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial libraries through an iterative in vitro screening process known as Systemic Evolution of Ligands by Exponential Enrichment (SELEX). In ... -
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ... -
In vitro measurement of hepatic flow distribution in Fontan vascular conduits: Towards rapid validation techniques
(Elsevier Ltd, 2022)Fontan operation is the last stage of single-ventricle surgical reconstructions that connects superior and inferior vena cava (SVC, IVC) to the pulmonary arteries. The key design objectives in total cavopulmonary connections ... -
A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task
(Elsevier B.V., 2022)Background: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet. New method: Here, we describe ... -
Plasmonic enhancement in PTB7-Th:PC71BM organic photovoltaics
(Elsevier B.V., 2022)Organic photovoltaics struggles with limited exciton diffusion rate and low light absorption rates. The trade-off between these deficiencies limits the thickness of the active layer around 100–200 nm range. Plasmonic light ... -
A novel fontan Y-graft for interrupted inferior vena cava and azygos continuation
(Elsevier Science, 2022)Objectives: To evaluate the hemodynamicdynamic advantage of a new Fontan surgical template that is intended for complex single-ventricle patients with interrupted inferior vena cava-azygos and hemi-azygos continuation. The ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
(American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Characterization and biological evaluation of crataegus azarolus fruit polysaccharides
(Elsevier B.V., 2022)The polysaccharide obtained from Crataegus azarolus fruit, by water extraction followed by ethanol precipitation and fractionation using copper complex, shows physiological activities: prebiotic and antioxidant. The total ... -
Radiation type- and dose-specific transcriptional responses across healthy and diseased mammalian tissues
(MDPI, 2022)Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but ... -
Selective binding of pVTK peptide-and bisphosphonate-functionalized micelles to prostate cancer cells, osteoblasts, and osteoclasts
(Andover House, Inc., 2022)This report describes the development of functionalized polymeric micelles encapsulating a chemotherapeutic agent. The results indicate the ability to achieve selective uptake into different cell populations in metastatic ...