Scopus Q Kategorisi "Q4" Makale Koleksiyonu İçin Listeleme
Toplam kayıt 26, listelenen: 1-20
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An alternative approach wound healing field with polypodium vulgare
(Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ... -
Antibiotic susceptibility of Klebsiella pneumoniae strains isolated from clinical samples
(Turkish Chemical Society, 2020)Antibiotic resistance in bacteria has become a worrying phenomenon in today's world. K. pneumoniae is a member of the Enterobacteriaceae family, which causes nosocomial infections as an opportunistic pathogen but inherently ... -
Antimicrobial activity evaluation of new 1,3,4-oxadiazole derivatives
(University of Istanbul, 2017)In this study, we have synthesized seven novel 2-[(5-(4-chlorobenzyl)-1,3,4-oxadiazol-2-yl)thio]-N-(6-substituted benzothiazol-2-yl)acetamide derivatives (4ag) starting from ethyl 4-chlorophenyl acetate. The antimicrobial ... -
Antioxidant activity of blackthorn (Prunus spinosa L.) fruit extract and cytotoxic effects on various cancer cell lines
(Logos Medical Publishing, 2019)Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects ... -
Comparison of 3 doses of aloe vera and burn drugs in market on burnt rat models
(İstanbul Medipol University, 2018)Burn injuries are an incident that can have serious traumatic consequences. Degree of tissue damage depends on height of heat and duration of contact. It can be classified as 4 different burn degrees. Herbal treatments can ... -
A contraindication to metfromin therapy: Renal impairment - Adherence to prescribing guidelines at a hospital in Turkey
(University of Istanbul, 2018)Objective: The aim of this study was to investigate whether renal functions of the patients were monitored and checked before and during metformin treatment as recommended in guidelines or whether they were disregarded and ... -
Design and synthesis of new donepezil analogs derived from arylpiperazine scaffold as acetylcholinesterase inhibitors
(Taylor & Francis Ltd, 2020)Newly synthesized 4-substituted phenyl-2-(4-substituted phenylpiperazine-1-yl)thiazole derivatives (4a-v) were evaluated in terms of their acetylcholinesterase (AChE) inhibition activities. Twenty-two compounds were tested ... -
The effects of some imidazopyrazine derivatives on telomerase inhibition, mtDNA damage and mtDNA copy number
(University of Istanbul, 2017)Imidazopyrazine derivatives have been studied for their curative effects on some diseases like cancer and neurological problems; also, some of these molecules have been patented. Primary human cells exhibit limited replicative ... -
The essential oils of two Achillea L. Species from Turkey
(İstanbul Medipol University, 2018)Chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Achillea biebersteinii Afan. and A. wilhelmsii C. Koch were analyzed by GC-FID and GC-MS. The essential oils of A. biebersteinii ... -
Evaluation of in situ gel containing pycnogenol for cutaneous wound healing
(Logos Medical Publishing, 2019)Aim: Pycnogenol® (PYC) are used for various medicinal purposes. The aims of the present study were toevaluate wound healing activity of PYC loaded in situ gel in mice and to investigate its antibacterial activity.Method: ... -
Evaluation of knowledge level about asbestos exposure in urban transformation construction areas
(University of Istanbul, 2017)Since Turkey is in an earthquake zone, historically there has been a lot of demolition in various cities, including Istanbul which contains many historical places. Residents of Istanbul are subject to calamity regulations ... -
Formulation of microemulsions for dermal delivery of Cephalexin
(University of Istanbul, 2017)Introduction: Cephalexin monohydrate (CEM) is mostly used because of its activity against both the gram-positive and gram-negative microorganisms for infections. Microemulsions offer numerous advantages for dermal delivery ... -
Identification and in vitro bioactivity screening of some marine-derived fungi from Turkish coastlines
(Cahiers de Biologie Marine, 2020)The marine environment represents a great variety of conditions of pressure, temperature, salinity, and light depending on depth, latitude and interactions with the continental shelf. These extreme and variable conditions ... -
In vitro antimicrobial and antioxidant activity of some berry species
(Istanbul Medipol University, 2018)The aim of this work was to determine antioxidant and antimicrobial activities of extracts obtained from fresh and dried fruits of Vaccinium macrocarpon, Morus nigra, Fragaria X ananassa. Antioxidant and antimicrobial ... -
Laurocerasus officinalis Roem. fruit extract induces cell death through caspase mediated apoptosis in gastric cancer cell lines
(Walter de Gruyter GmbH, 2021)Objectives: Laurocerasus officinalis Roem. fruits are traditionally used for several health problems. Although there are some studies about its antiproliferative effects on different cancer cells, no study was reported ... -
Miyokardiyal iskemi sonrası gelişen akut böbrek hasarı üzerine Nebivolol’ün etkisi: Preklinik bir çalışma
(Galenos Yayıncılık, 2018)Amaç: Akut miyokard iskemisinin reperfüzyonu (IR) sırasında miyokard dokusunun yanı sıra diğer dokularda da hasarın söz konusu olduğu gösterilmiştir. Böbrek hasarı bunlardan birisidir. Altta yatan mekanizmalara yönelik pek ... -
Molecular modelling and activity analysis of mycobacterium tuberculosis DNA gyrase B ATPase active site
(University of Istanbul, 2017)Computer-based algorithms and statistical techniques such as receiver operating characteristic (ROC) curves are increasingly used for the design of new ligands. X-ray crystallographic data and homology models allow examining ... -
Molecular modelling and compound activity of the escherichia coli and staphylococcus aureus DNA gyrase B ATPase site
(University of Istanbul, 2017)Development of new treatment ligands that can distinguish Escherichia coli (E. coli) from Staphylococcus aureus (S. aureus) is important because of bacterium multiple drug resistance. High-throughput virtual screening ... -
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
(Istanbul University Press, 2023)Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ... -
Novel benzothiazole based imidazole derivatives as new cytotoxic agents against glioma (C6) and liver (HepG2) cancer cell lines
(University of Istanbul, 2017)In this work, some novel N-(6-substituted-benzothiazol-2-yl)-2-[[4,5-dimethyl-1-((p-tolyl/4-nitrophenyl)amino)-1H-imidazol-2-yl]thio]acetamide derivatives were synthesized and searched for their cytotoxic activities against ...