Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 280, listelenen: 141-160
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New therapeutic system based on hydrogels for vaginal candidiasis management: Formulation-characterization andin vitroevaluation based on vaginal irritation and direct contact test
(Taylor and Francis Ltd., 2020)The objective of the present research was to examine the possible usage of terbinafine loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal candidiasis belongs to the most frequent ... -
Investigation of antibacterial activity of juglone-poly(ε-caprolactone) - Alumina composite films
(Sakarya University, 2021)The aim of this study was to produce the Poly(ε-caprolactone)(PCL)-Alumina (Al2O3) composite films impregnated with Juglone and determine their antibacterial properties. PCLAl2O3 composite films containing 1% and 5% Juglone ... -
Volatile components and antimicrobial activity of the N-Hexane extracts of neomuretia pisidica (Kit tan) Kljuykov, Degtjareva & Zakharova
(Badebio Biotechnololgy Ltd., 2021)The fruits, aerial parts and roots of Neomuretia pisidica (Kit Tan) Kljuykov, Degtjareva & Zakharova were extracted with n-hexane. Total of 18 compounds were characterised by GC analyses of the n-hexane extracts. Main ... -
Synthesis, characterization and antibacterial evaluation of new pyridyl-thiazole hybrids of sulfonamides
(Istanbul University, 2021)Background and Aims: Sulfonamide drugs are a very old and noted group of small molecules, and are still one of the most important antimicrobial compounds. In this study, starting from sulfonamide drugs, new original compounds ... -
The influence of different extraction methods/solvents on composition, biological activities and ADMET predictions of phenolics in tribulus terrestris
(Instituto de Tecnologia do Parana, 2021)Tribulus terrestris is a plant that has medical importance in treating diseases such as cancer, urinary tract infections, kidney stones, rheumatism, and hypertension. The aim of this study is to examine the effects of ... -
Sağlık öğrencilerinde aşı tereddüdü
(Hayat Sağlık ve Sosyal Hizmetler Vakfı, 2021)Amaç: Bu çalışmada İstanbul’da sağlık alanında (tıp, diş hekimliği, eczacılık, hemşirelik, ebelik, fizik tedavi ve rehabilitasyon, diyetisyenlik, odyoloji, sağlık yönetimi) yükseköğrenim görmekte olan öğrencilerin aşı ... -
Biological activities of the Ornithogalum orthophyllum and its in silico ADMET profile
(TMR Publishing Group, 2021)Background: The bulbs and aerial parts of Ornithogalum are used in Turkey both as food and to treat various ailments, and some of its medical applications are well known. However, the biological activities of Ornithogalum ... -
Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils
(Consejo Superior de Investigaciones Científicas (CSIC), 2021)The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One ... -
Butyrylcholinesterase-inhibiting natural coumarin molecules as potential leads
(Elsevier Ltd, 2021)Seventeen natural coumarin derivatives; badrakemin (1), 14′-acetoxybadrakemin (2), badrakemone (3), 14′-acetoxybadrakemone (4), colladonin (5), colladonin acetate (6), 14′-acetoxycolladonin (7), karatavicinol (8), deltoin ... -
In vitro ACE2 and 5-LOX enzyme inhibition by menthol and three different mint essential oils
(SAGE Publications Inc., 2021)Mentha arvensis L., M. citrata L., and M. spicata L. (family Lamiaceae) essential oils, and their characteristic constituent, menthol, were evaluated in vitro for angiotensin converting enzyme 2 (ACE2) and 5-lipoxygenase ... -
Novel cyanothiouracil and cyanothiocytosine derivatives as concentration-dependent selective inhibitors of U87MG glioblastomas: Adenosine receptor binding and potent PDE4 inhibition
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2021)Thiouracil and thiocytosine are important heterocyclic pharmacophores having pharmacological diversity. Antitumor and antiviral activity is commonly associated with thiouracil and thiocytosine derivatives, which are well ... -
Anti-inflammatory, analgesic and in vivo-in vitro wound healing potential of the Phlomis rigida Labill. extract
(Elsevier Ireland Ltd, 2021)Ethnopharmacological relevance: The preparations of Phlomis aerial parts are used traditionally in Anatolia for wound healing and in inflammatory disorders. Methods: For the identification of the active fraction, the air ... -
HPLC-FRAP methodology and biological activities of different stem bark extracts of Cajanus cajan (L.) Millsp
(Elsevier, 2021)Cajanus cajan. (L.) Millsp. (C. cajan) (Family: Fabaceae) also known as pigeon pea, is a famous food and cover/forage crop bearing a high amount of key amino acids (methionine, lysine and tryptophan). This study investigated ... -
Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica
(ACG Publications, 2021)Preliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent ... -
Evaluation of probiotic use of the students of Istanbul Medipol University
(İstanbul Medipol University, 2021)This research; is planned to determine the level of knowledge about probiotic nutri-tions and, the consumption of them by university students. The date range of the study was 2018. A total of 100 students were surveyed at ... -
Formulation development of liposomal coffee extracts and investigation of their antioxidant capacities
(Elsevier, 2021)he main objective of this study was to carry out the antioxidant capacity of a liposomal formulation either green coffee extract (GCE) and medium roasted coffee extract (RCE) in aq. and MeOH. First, the coffee beans were ... -
Phthalocyanine-conjugated glyconanoparticles for chemo-photodynamic combination therapy
(NLM (Medline), 2021)Combination cancer therapy based on multifunctional nanomaterials has attracted great attention. The present work focuses on the preparation of the glycopolymeric nanoparticle, which contains a photosensitizer (zinc(II)p ... -
Evaluation of medication and herbal product use among pregnant women
(Istanbul Medipol University, 2021)The use of medications and herbal products among women increases after pregnancy. The purpose of the study is to evaluate the frequency of medication used and analyzed them based on the FDA pregnancy risk categories. This ... -
Türk popülasyonunda XRCC1 (Arg399Gln) ve XRCC3 (Thr241Met) polimorfizmlerinin genotip dağılımı ve Allel frekanslarının belirlenmesi
(Galenos Yayınevi, 2021)Amaç: XRCC1 geni, serbest oksijen radikallerinin, iyonize radyasyonun, ultraviyole ve alkilleyici mutajenlerin yaptığı baz değişimi sonucu oluşan baz kesip çıkarma (eksizyon) onarımı ve DNA tek zincir kırılmalarının ... -
Laurocerasus officinalis Roem. fruit extract induces cell death through caspase mediated apoptosis in gastric cancer cell lines
(Walter de Gruyter GmbH, 2021)Objectives: Laurocerasus officinalis Roem. fruits are traditionally used for several health problems. Although there are some studies about its antiproliferative effects on different cancer cells, no study was reported ...