Yazar "Baykal, Ahmet Tarık" için Makale Koleksiyonu listeleme
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Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl
Sibai, Mustafa; Altuntaş, Ebru; Süzek, Barış Ethem; Şahin, Betül; Parlayan, Cüneyd; Öztürk, Gürkan; Baykal, Ahmet Tarık; Demircan, Turan (Elsevier, 2020)The axolotl (Ambystoma mexicanum) salamander, a urodele amphibian, has an exceptional regenerative capacity to fully restore an amputated limb throughout the life-long lasting neoteny. By contrast, when axolotls are ... -
Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database
Demircan, Turan; Keskin, İlknur; Dumlu, Seda Nilgün; Aytürk, Nilüfer; Avşaroğlu, Mahmut Erhan; Akgün, Emel; Öztürk, Gürkan; Baykal, Ahmet Tarık (Wiley, 2017)Salamander axolotl has been emerging as an important model for stem cell research due to its powerful regenerative capacity. Several advantages, such as the high capability of advanced tissue, organ, and appendages ... -
Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival
Yalçın, Esra; Beker, Mustafa Çağlar; Türkseven, Şeyma; Çağlayan, Berrak; Gürel, Büşra; Kılıç, Ülkan; Çağlayan, Ahmet Burak; Kalkan, Rabia; Baykal, Ahmet Tarık; Keleştemur, Taha; Kılıç, Ertuğrul (Academic Press Inc Elsevier Science, 2019)Indolamine melatonin structurally resembles non-covalent proteasome inhibitors; however, the role of ubiquitin proteasome system (UPS) in neuronal survival and how melatonin carries out UPS inhibition remain largely unknown. ... -
Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
Beker, Mustafa Çağlar; Çağlayan, Berrak; Çağlayan, Ahmet Burak; Kelestemur, Taha; Yalçın, Esra; Çağlayan, Aysun; Kılıç, Ülkan; Baykal, Ahmet Tarık; Reiter, Russel J.; Kılıç, Ertuğrul (Nature Publishing Group, 2019)The circadian rhythm is driven by a master clock within the suprachiasmatic nucleus which regulates the rhythmic secretion of melatonin. Bmal1 coordinates the rhythmic expression of transcriptome and regulates biological ... -
Neonatal neurodegeneration in alzheimer's disease transgenic mouse model
Mazi, Aişe Rümeysa; Arzuman, Ayşegül Sümeyye; Gürel, Büşra; Şahin, Betül; Tüzüner, Mete Bora; Ozansoy, Mehmet; Baykal, Ahmet Tarık (IOS Press, 2018)Alzheimer's disease (AD) is a progressive disorder characterized by a variety of molecular pathologies causing cortical dementia with a prominent memory deficit. Formation of the pathology, which begins decades before the ...