• Systematic review and meta-analysis of tocilizumab therapy versus standard of care in over 15,000 COVID-19 pneumonia patients during the first eight months of the pandemic 

  Mahroum, Naim; Watad, Abdulla; Bridgewood, Charlie; Mansour, Muhammad; Nasr, Ahmad; Hussein, Amr; Khamisy-Farah, Rola; Farah, Raymond; Gendelman, Omer; Lidar, Merav; Shoenfeld, Yehuda; Amital, Howard; Kong, Jude Dzevela; Wu, Jianhong; Bragazzi, Nicola Luigi; McGonagle, Dennis (MDPI, 2021)

  Background. Tocilizumab is an anti-IL-6 therapy widely adopted in the management of the so-called "cytokine storm" related to SARS-CoV-2 virus infection, but its effectiveness, use in relation to concomitant corticosteroid ...

• Use of favipiravir in lactating mother with COVID-19 

  Karabayır, Nalan; Öcal Doğan, Özlem; Canbeyli, Gülçin (AVES, 2021)

  ...

• Management of adults with suspected foreign body aspiration 

  Uğur Chousein, Efsun Gonca; Tanrıverdi, Elif; Turan, Demet; Yıldırım, Binnaz Zeynep; Yılmaz, Şeyma; Chousein, İrfan; Özgül, Mehmet Akif; Çetinkaya, Erdoğan (Dicle University, 2021)

  Objective: Although foreign body aspiration (FBA) in adulthood is not as common as in childhood, it can sometimes be encountered with clinical situations that require urgent interventions. Removal of foreign bodies (FBs) ...

• Global consensus recommendations on menopause in the workplace: A European Menopause and Andropause Society (EMAS) position statement 

  Rees, Margaret; Bitzer, Johannes; Cano, Antonio; Ceausu, Iuliana; Chedraui, Peter; Durmuşoğlu, Fatih; Erkkola, Risto; Geukes, Marije; Godfrey, Alan; Goulis, Dimitrios G.; Griffiths, Amanda; Hardy, Claire; Hickey, Martha; Hirschberg, Angelica Linden; Hunter, Myra; Kiesel, Ludwig; Jack, Gavin; Lopes, Patrice; Mishra, Gita; Oosterhof, Henk; Pines, Amos; Riach, Kathleen; Shufelt, Chrisandra; van Trotsenburg, Mick; Weiss, Rachel; Lambrinoudaki, Irene (Elsevier Ireland Ltd, 2021)

  Introduction: Worldwide, there are 657 million women aged 45-59 and around half contribute to the labor force during their menopausal years. There is a diversity of experience of menopause in the workplace. It is shaped ...

• Analysis of pregnancy and lactation-related expressions in the summary of product characteristics and patient information leaflets of the drugs used for the treatment of nausea and vomiting 

  Aydın, Volkan; Bahar, Ayfer; Bayram, Dilara; Vızdıklar, Caner; Akıcı, Ahmet (Galenos Yayıncılık, 2021)

  Objective: Concerns and limited data on drug use in pregnancy and lactation raise the importance of relevant information in summary of product characteristics (SmPC) and patient information leaflets (PIL). This study aimed ...

• Severe acute respiratory syndrome coronavirus-2 antigens and antibodies in breast milk 

  Keskindemirci, Gonca; Karabayır, Nalan; İstanbullu Tosun, Ayşe; Hançerli Torun, Selda; Altay, Ceren Sultan; Sebirli, Muhammet; Kaba, Özge; Kibar, Büşra Sultan; Gökçay, Gülbin (Istanbul University, 2021)

  Objective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 ...

• Utilization of biotechnological drugs in rare diseases requiring the use of off-label drugs in children in Turkey 

  Kırmızı, Neriman İpek; Aydın, Volkan; Akıcı, Narin; Bayar, Banu; Akıcı, Ahmet (TÜBİTAK Scientific and Technological Research Council of Turkey, 2021)

  Background/aim: Pediatric patients, especially those with rare diseases, represent a population that has a high tendency towards off label drug use (OLDU) and needs a more careful practice of pharmacotherapy than in adults. ...

• Evaluation of chirality for withdrawn drugs 

  Bahar, Ayfer; Vızdıklar, Caner; Aydın, Volkan; Akıcı, Ahmet (Wiley, 2021)

  ...

• Comparison of pediatric antibiotherapy in primary care: Low vs. high prescribers 

  Aydın, Volkan; Kırmızı, Neriman İpek; Ataç, Ömer; Akıcı, Narin; Akıcı, Ahmet (Wiley, 2021)

  ...

• Investigation of diclofenac and paracetamol prescribing for adults in primary care 

  Şanlı, Abdullah; Bayram, Dilara; Abanoz, Mustafa Naci; Pala, Sedat; Sıbıç, Büşra; Aydın, Volkan; Ataç, Ömer; Akıcı, Ahmet (Wiley, 2021)

  ...

• Which ultrasound or MRI characteristics demonstrate the highest diagnostic accuracy in identifying malignancy in males with indeterminate lesions of the testis? A systematic review 

  Ager, M.; Salonia, A.; Mayo De Castro, J.; Donaldson, J.; Omar, M. I.; Dimitrpoulos, K.; Tharakan, T.; Boeri, L.; Janisch, F.; Muilwijk, T.; Nijman, R.; Radmayr, C.; del Pilar Laguna Pes, Maria; Minhas, S. (Elsevier, 2021)

  ...

• Effect of inspiratory muscle training on dyspnea-related kinesiophobia in chronic obstructive pulmonary disease: A randomized controlled trial 

  Saka, Seda; Gürses, Hülya Nilgün; Bayram, Mehmet (Elsevier Ltd, 2021)

  Background: The major symptom of chronic obstructive pulmonary disease (COPD) is dyspnea, which causes dyspnea-related kinesiophobia resulting in avoidance of activities associated with dyspnea or compensation by reducing ...

• A rational design of multi-functional nanoplatform: Fluorescent-based “off-on” theranostic gold nanoparticles modified with D-α-Tocopherol succinate 

  Demiral, Ayşegül; Verimli, Nihan; Goralı, İrem; Yılmaz, Hülya; Çulha, Mustafa; Erdem, Sultan Sibel (Elsevier B.V., 2021)

  It is crucial to develop nanocarrier systems to detect and treat drug-resistant micro tumors to prevent recurrence and/or metastasis of cancer. Due to their exceptional features such as biocompatibility, easy surface ...

• Effect of social isolation on the brain injury following focal cerebral ischemia in mice and proteomic approach for identifying possible cellular pathways 

  Çağlayan, A. B.; Daşdelen, M. F.; Beker, M. C.; Özbay, E.; Kılıç, E. (Wiley, 2021)

  ...

• Recommendations to balance benefits and risks of thromboprophylaxis and to avoid central venous-access devices during first-line chemotherapy in men with metastatic germ cell tumors: The European Association Of Urology Testicular Cancer Panel Position in 2021 

  Fankhauser, Christian Daniel; Oldenburg, Jan; Albers, Peter; Algaba, Ferran; Bokemeyer, Carsten; Boormans, Joost L.; Fischer, Stefanie; Fizazi, Karim; Gremmels, Hendrik; Mayor de Castro, Javier; Janisch, Florian; Muilwijk, Tim; Leao, Ricardo; Nicol, David; Nicolai, Nicola; Tandstad, Torgrim; del Pilar Laguna Pes, Maria (Elsevier, 2021)

  Recent randomized controlled trials have assessed the risksand benefits of thromboprophylaxis in ambulatory cancerpatients receiving chemotherapy and reported a relativerisk reduction of 30–60% in venous thromboembolic ...

• Epidemic Klebsiella pneumoniae ST258 incidence in ICU patients admitted to a university hospital in Istanbul 

  Ünlü, Özge; Ersöz, Berken Rabun; İstanbullu Tosun, Ayşe; Demirci, Mehmet (Journal of Infection in Developing Countries, 2021)

  Introduction: Klebsiella pneumoniae sequence type 258 (ST258) strains are globally distributed multi-drug resistant pathogens and can spread rapidly throughout the world, causing severe healthcare-associated invasive ...

• Topical estrogens and non-hormonal preparations for postmenopausal vulvovaginal atrophy: An EMAS clinical guide 

  Hirschberg, Angelica Linden; Bitzer, Johannes; Cano, Antonio; Ceausu, Iuliana; Chedraui, Peter; Durmuşoğlu, Fatih; Erkkola, Risto; Goulis, Dimitrios G.; Kiesel, Ludwig; Lopes, Patrice; Pines, Amos; van Trotsenburg, Mick; Lambrinoudaki, Irene; Rees, Margaret (Elsevier Ireland Ltd, 2021)

  Introduction: Vulvovaginal atrophy (VVA) is a chronic condition caused by estrogen deficiency. It affects around 50% of postmenopausal women, reducing their general and sexual quality of life as well as the quality of their ...

• Contemporary patterns of presentation, diagnostics and management of upper tract urothelial cancer in 101 centres: The Clinical Research Office of the Endourological Society Global upper tract urothelial carcinoma registry 

  Baard, Joyce; Cormio, Luigi; Cavadas, Vítor; Alcaraz, Antonio; Shariat, Shahrokh F.; de la Rosette, Jean J. M. C. H.; Laguna, María Pilar (NLM (Medline), 2021)

  PURPOSE OF REVIEW: To assess patterns of presentation, diagnostics and treatment in patients with upper tract urothelial carcinoma (UTUC), a multicentre registry was launched. Clinical data of UTUC patients were prospectively ...

• Antiviral activity of different extracts of standardized propolis preparations against HSV 

  Demir, Sevda; Atayoğlu, Ali Timuçin; Galeotti, Fabio; Garzarella, Emanuele U.; Zaccaria, Vincenzo; Volpi, Nicola; Karagöz, Ali; Şahin, Fikrettin (International Medical Press Ltd, 2021)

  Background: Viral infections are among the most common problems in health-care practice. Natural products offer great promise as potentially effective antiviral drugs. Propolis is a honeybee product with biological properties ...

• Comparison of catheter-directed thrombolysis and anticoagulation in intermediate-risk pulmonary embolism: A retrospective analysis 

  Özden Omaygenç, Derya; Omaygenç, Mehmet Onur (Wolters Kluwer Medknow Publications, 2021)

  BACKGROUND AND OBJECTIVES: The selection of escalation of care strategies for the treatment of intermediate-risk pulmonary embolism (PE) is a matter of debate. Here, we aimed to assess the features of our population treated ...

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