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Recent Submissions
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A multi-center international study to evaluate the safety, functional and oncological outcomes of irreversible electroporation for the ablation of prostate cancer
(2024)Background: Irreversible electroporation (IRE) is a novel technique to treat localized prostate cancer with the aim of achieving oncological control while reducing related side effects. We present the outcomes of localized ... -
Impact of pre-operative ureteroscopy on bladder recurrence following nephroureterectomy for utuc
(2024)(1) Introduction: Diagnostic ureteroscopy (URS) is an important component in the workup of upper tract urothelial carcinoma (UTUC). Whether URS was associated with increased recurrence in the bladder was not fully concluded. ... -
Vaccine-induced strain replacement: theory and real-life implications
(2024)The value of preventive medicine is superior to treatment with vaccinations occupying high priority. Nevertheless, heavy pressure has started to form in regard to strains not included in vaccines contributing to the changing ... -
Medication-related osteonecrosis of the jaw: bibliometric analysis from 2003 to 2023
(2024)Medication-related osteonecrosis of the jaw (MRONJ) is a serious condition associated with the use of antiresorptive and antiangiogenic medications. Despite extensive research, the pathophysiology of MRONJ remains poorly ... -
A novel autosomal recessive candidate gene responsible for rasopathy-like phenotype and bone marrow failure: rasa3
(2024)Although many genetic etiologies, such as Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis congenita, and Diamond-Blackfan anemia, from hereditary bone marrow failure are known today, the responsible gene remains ... -
A survey of artificial intelligence/machine learning-based trends for prostate cancer analysis
(2024)Different types of cancer are more commonly encountered recently. This may be attributed to a variety of reasons, including heredity, changes in the living conditions (food, drinks, pollution, etc.), advancement in technology ... -
Patterns and trends in continuous glucose monitoring utilization among commercially insured individuals with type 1 diabetes: 2010-2013 to 2016-2019
(2024)Prior studies suggest that only ∼30% of patients with type 1 diabetes use continuous glucose monitoring (CGM), but most studies to date focused on children and young adults seen by endocrinologists or in academic centers. ... -
Comparison of outcomes and recurrence rates in patients undergoing single or double burr hole surgery for the treatment of chronic subdural hematoma in Bosnia and Herzegovina
(2024)Introduction: Chronic subdural hematoma (CSDH) is a prevalent condition commonly seen in elderly individuals, often requiring neurosurgical intervention. Research question: This study investigates patient characteristics ... -
Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
(2024)Metabolic enzymes can adapt during energy stress, but the consequences of these adaptations remain understudied. Here, we discovered that hexokinase 1 (HK1), a key glycolytic enzyme, forms rings around mitochondria during ... -
Tobacco use in breastfeeding mothers
(Springer International Publishing, 2023)Smoking is a major health hazard that remains very common worldwide. Nicotine is a highly addictive substance. There are in excess of 250 million female smokers globally. When expectant mothers continue to smoke, they not ... -
Bridging the gap: a narrative review of osteoporosis disability, adipokines, and the role of AI in postmenopausal women
(2024)Osteoporosis is a global health concern characterized by reduced bone density and compromised bone quality, resulting in an increased risk of fractures, particularly in postmenopausal women. The assessment of bone mineral ... -
Remote monitoring app for endocrine therapy adherence among patients with early-stage breast cancer: a randomized clinical trial
(2024)Importance: Adjuvant endocrine therapy (AET) use among women with early-stage, hormone receptor-positive breast cancer reduces the risk of cancer recurrence, but its adverse symptoms contribute to lower adherence. Objective: ... -
Global practice patterns in the evaluation of non-obstructive azoospermia: results of a world-wide survey and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, ... -
Global practice patterns and variations in the medical and surgical management of non-obstructive azoospermia: results of a world-wide survey, guidelines and expert recommendations
(2024)Purpose: Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and a lack of clear guidelines. Hence, there is considerable controversy and marked variation in the management ... -
IMpassion132 double-blind randomised phase III trial of chemotherapy with or without atezolizumab for early relapsing unresectable locally advanced or metastatic triple-negative breast cancer
(2024)Background: Immune checkpoint inhibitors improve the efficacy of first-line chemotherapy for patients with programmed death-ligand 1 (PD-L1)-positive unresectable locally advanced/metastatic triple-negative breast cancer ... -
Use of geological maps in detecting asbestos-related diseases; a new region in Anatolia
(2024)Objective: To examine the potential relationship between the presence of asbestos-related diseases (ARDs) in the region of Kastamonu, Turkey. Methods: The birthplaces of patients with ARDs and control subjects diagnosed ... -
Supratherapeutic utilization of paracetamol versus ibuprofen among <12-year-old children in primary care in Istanbul
(2024)Background: Paracetamol and ibuprofen are the most preferred analgesics for pain and fever management in children. Prescribing of these drugs in supratherapeutic doses may predispose to their toxicity. We aimed to compare ... -
Effectiveness of intermittent theta burst stimulation to enhance upper extremity recovery after stroke: A randomized controlled study
(2024)Objective: To first investigate the effectiveness of modified Constraint-Induced Movement Therapy (mCIMT) in low-functioning patients with stroke (PwS). Second, we aimed to investigate the efficiency of intermittent ...