• Identification of PDE10A related proteins via proteomic analysis 

  Beker, Mustafa Çağlar; Yelkenci, Hayriye Ecem; Çağlayan, Berrak; Kılıç, Ertuğrul (İnönü University Faculty of Medicine, 2022)

  Aim: Phosphodiesterase 10A (PDE10A) regulates the expression of secondary messengers of cyclic adenosine monophosphate and cyclic guanosine monophosphate, which control several intracellular signaling pathways. Recently, ...

• Quality of life assessment with EORTC QLQ in patients with multiple myeloma: Multicenter study 

  Gemici, Aliihsan; Serin, İstemi; Erol, Vedat Buğra; Doğu, Mehmet Hilmi; İnce, İdris; Eren, Rafet; Tekinalp, Atakan; Karakuş, Volkan; Koç Erol, İklil Nur; Arslan, Zeynep Ece; Tay, Zekiye Nur; Tuncer, Elif Nur; Sevindik, Ömür Gökmen (Galenos Publishing House, 2022)

  Objective: Both the length of the treatment period and the diversity of the agents used in the treatment significantly affect the quality of life (QoL) of the patients with multiple myeloma (MM). With the aid of the EORTC ...

• The impact of COVID-19 pandemic on mental health of health care workers 

  Bener, Abdulbari; Atak, Muhammed; Kurtuluş, Dilara; Koyuncu, Oğuzhan; Barışık, Cem Cahit; Bhugra, Dinesh; Ventriglio, Antonio (Edizioni Minerva Medica, 2022)

  Background: this study investigated the impact of cOViD-19 on professional (hcWs) health care workers’ mental health and the prevalence of depression, anxiety, fear and stress related to their workload. METHODS: This is a ...

• A multicenter, randomized, single-blind, 2-arm intervention study evaluating the adverse events and quality of life after irreversible electroporation for the ablation of localized low-intermediate risk prostate cancer 

  de la Rosette, Jean J. M. C. H.; Dominguez-Escrig, Jose; Zhang, Kai; Teoh, Jeremy; Barret, Eric; Ramon-Borja, Juan Casanova; Muir, Gordon; Bohr, Julia; de Reijke, Theo; Ng, Chi-Fai; Leung, Chi-Ho; Sanchez-Salas, Rafael; del Pilar Laguna Pes, Maria (NLM (Medline), 2023)

  PURPOSE: Our goal was to evaluate the effect of focal vs extended irreversible electroporation on side effects, patient-reported quality of life, and early oncologic control for localized low-intermediate risk prostate ...

• Utilization trend of gastric acid-suppressing agents in relation to analgesics 

  Kırmızı Sönmez, Neriman İpek; Aydın, Volkan; Akıcı, Ahmet (Wiley, 2022)

  Background: Controversies exist about excessive use of gastric acid-suppressing agents or lack of adequate indications, especially when co-prescribed with analgesics for gastroprotection. We aimed to analyze the nationwide ...

• Evaluation of nutritional status with Healthy Eating Index (HEI-2010) of syrian refugees living outside the refugee camps 

  Atayoğlu, Ali Timuçin; Fırat, Yağmur; Kaya, Neşe; Başmısırlı, Eda; Çapar, Aslı Gizem; Aykemat, Yusuf; Atayolu, Rümeysa; Khan, Hammad; Güner Atayoğlu, Ayten; İnanç, Neriman (MDPI, 2023)

  Nutrition is a public health issue. Amongst populations of refugees, unmet nutritional needs have been identified. The aim of this study was to evaluate the nutritional status of Syrian refugees living outside the refugee ...

• The COVID-19 pandemic – How many times were we warned before? 

  Mahroum, Naim; Seida, İsa; Esirgün, Şevval Nil; Bragazzi, Nicola Luigi (Elsevier B.V., 2022)

  Infectious diseases are known to act in both predictable and unpredictable ways, which leads to the notions of emerging and reemerging infectious diseases. Emerging diseases with their disastrous consequences might be ...

• The association of chiral characteristic with drug withdrawal due to safety: A comparative analysis 

  Aydın, Volkan; Bahar, Ayfer; Vızdıklar, Caner; Akıcı, Ahmet (Wiley, 2023)

  Aims Chirality of drugs might be associated with safety issues through pharmacokinetic or pharmacodynamic variations, interactions, or direct toxicological responses. We aimed to compare chiral status of the available drugs ...

• Super-mini percutaneous nephrolithotomy (SMP) vs retrograde intrarenal surgery (RIRS) in the management of renal calculi <= 2 cm: A propensity matched study 

  Pillai, Sunil Bhaskara; Chawla, Arun; de la Rosette, Jean J. M. C. H.; del Pilar Laguna Pes, Maria; Guddeti, Rajsekhar; Reddy, Suraj Jayadeva; Sabnis, Ravindra; Ganpule, Arvind; Desai, Mahesh; Parikh, Aditya (Springer, 2022)

  Objective: To compare the effectiveness and safety of Super-Mini PCNL (SMP) and Retrograde Intrarenal Surgery (RIRS) in the management of renal calculi ≤ 2 cm. Patients and methods: A prospective, inter-institutional, ...

• Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS 

  İlter, Metehan; Kaşmer, Ramazan; Jalalypour, Farzaneh; Atılgan, Canan; Topçu, Ozan; Karakaş, Nihal; Şensoy, Özge (NLM (Medline), 2022)

  Undruggability of RAS proteins has necessitated alternative strategies for the development of effective inhibitors. In this respect, phosphorylation has recently come into prominence as this reversible post-translational ...

• Weak association between arterial hypertension and overactive bladder baseline symptoms and treatment responses 

  Michel, Martin C.; Heemann, Uwe; de la Rosette, Jean J. M. C. H. (Frontiers Media S.A., 2022)

  While animal studies have suggested an association between the presence of hypertension and the presence and/or severity of overactive bladder syndrome (OAB) symptoms, little clinical data is available. We have conducted ...

• Infectious side effects of baricitinib: A big data analysis based on VigiBase 

  Mahroum, Naim; Özkan, Mehmet Fatih; Abalı, Tunahan; Yılmaz, Mesut; Bragazzi, Nicola Luigi (Elsevier B.V., 2023)

  Dear Editor, Baricitinib (known as “Olumiant”), is an inhibitor of Janus- associated kinase 1 and 2 (JAK1 and JAK2) initially introduced for the treatment of rheumatoid arthritis (RA), and later for systemic lupus erythematosus ...

• EMAS position statement: Vitamin D and menopausal health 

  Anagnostis, Panagiotis; Livadas, Sarantis; Goulis, Dimitrios G.; Bretz, Silvia; Ceausu, Iuliana; Durmuşoğlu, Fatih; Erkkola, Risto; Fistonic, Ivan; Gambacciani, Marco; Geukes, Marije; Hamoda, Haitham; Hartley, Caoimhe; Hirschberg, Angelica Lindén; Meczekalski, Blazej; Mendoza, Nicolas; Mueck, Alfred; Smetnik, Antonina; Stute, Petra; van Trotsenburg, Mick; Rees, Margaret; Lambrinoudaki, Irene (Elsevier Ireland Ltd, 2023)

  Introduction: There is increasing evidence that vitamin D has widespread tissue effects. In addition to osteoporosis, vitamin D deficiency has been associated with cardiovascular disease, diabetes, cancer, infections and ...

• Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke 

  Beker, Mustafa Çağlar; Çağlayan, Ahmet Burak; Altunay, Serdar; Özbay, Elif; Ateş, Nilay; Keleştemur, Taha; Çağlayan, Berrak; Kılıç, Ülkan; Doeppner, Thorsten Roland; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Springer, 2022)

  Phosphodiesterase 10A (PDE10A) hydrolyzes adenosine 3 ',5 '-cyclic monophosphate (cAMP) and guanosine 3 ',5 '-cyclic monophosphate (cGMP). It is highly expressed in the striatum. Recent evidence implied that PDE10A may be ...

• Concomitant bladder tumor is a risk factor for bladder recurrence but not upper tract 

  Liu, Kang; Zhao, Hongda; Alvarez-Maestro, Mario; Gravas, Stavros; Van Renterghem, Koen; Zeng, Guohua; Ng, Chi-Fai; del Pilar Laguna Pes, Maria; Teoh, Jeremy Yuen-Chun; de la Rosette, Jean J. M. C. H. (MDPI, 2022)

  Objective: To evaluate the clinical outcomes of UTUC patients with or without concurrent bladder tumor. Design, Setting, and Participants: The Clinical Research Office of the Endourology Society-Urothelial Carcinomas of ...

• Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) in predicting systemic inflammatory response syndrome (SIRS) and sepsis after percutaneous nephrolithotomy (PNL) 

  Kriplani, Akshay; Pandit, Shruti; Chawla, Arun; de la Rosette, Jean J. M. C. H.; del Pilar Laguna Pes, Maria; Reddy, Suraj Jayadeva; Somani, Bhaskar K. (Springer, 2022)

  The objective of this prospective observational study was to assess the clinical significance of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) as potential biomarkers ...

• Instant determination of the artemisinin from various Artemisia annua L. extracts by LC-ESI-MS/MS and their in-silico modelling and in vitro antiviral activity studies against SARS-CoV-2 

  Doğan, Kübra; Erol, Ebru; Orhan, Müge Didem; Değirmenci, Zehra; Kan, Tuğçe; Güngör, Ayşen; Yaşa, Belkıs; Avşar, Timuçin; Çetin, Yüksel; Durdağı, Serdar; Güzel, Mustafa (Wiley, 2022)

  Introduction Numerous efforts in natural product drug development are reported for the treatment of Coronavirus. Based on the literature, among these natural plants Artemisia annua L. shows some promise for the treatment ...

• Post-COVID-19 pain syndrome: A descriptive study in Turkish population 

  Topal, İlknur; Özçelik, Necdet; Atayoğlu, Ali Timuçin (Korean Pain Society, 2022)

  Background: The new type of corona virus has a wide range of symptoms. Some people who have COVID-19 can experience long-term effects from their infection, known as post-COVID conditions. The authors aimed to investigate ...

• European association of urology section of urolithiasis and international alliance of urolithiasis joint consensus on retrograde intrarenal surgery for the management of renal stones 

  Zeng, Guohua; Zhao, Zhijian; Mazzon, Giorgio; Pearle, Margaret; Choong, Simon; Skolarikos, Andreas; Denstedt, John; Seitz, Christian; Olvera Pasada, Daniel; Fiori, Cristian; Bosio, Andrea; Papatsoris, Athanasios; Méndez Probst, Carlos Enrique; Perez Fentes, Daniel; Ann Git, Kah; Wu, Qinghui; Wiseman, Oliver; Emiliani, Esteban; Farahat, Yasser; Gökçe, Mehmet İlker; Giannakopoulos, Stilianos; Goumas Kartalas, Ioannis; Somani, Bhaskar; Knoll, Thomas; de la Rosette, Jean J.M.C.H.; Zhong, Jiehui; Vinicius Maroccolo, Marcus; Saltirov, lliya; Chew, Ben; Wang, Kunjie; Lahme, Sven; Giusti, Guido; Ferretti, Stefania; Yong Cho, Sung; Geavlete, Petrisor; Cansino, Ramon; Kamphuis, Guido M.; Smith, Daron; Matlaga, Brian R.; Ghani, Khurshid D.; Bernardo, Norberto; Silva, Andres D.; Ng, Anthony C.F.; Yang, Sixing; Gao, Xiaofeng; Traxer, Olivier; Miernik, Arkadiusz; Liatsikos, Evangelos; Priyakant Parikh, Kandarp; Duvdevani, Mordechai; Celia, Antonio; Yasui, Takahiro; Aquino, Albert; Alomar, Mohammad; Choonhaklai, Vorapot; Erkurt, Bulent; Glass, Jonathan; Sriprasad, Seshadri; Osther, Palle J.; Keeley, Francis X.; Preminger, Glenn M.; Cepeda Delgado, Marcos; Beltran Suarez, Edgar; Ye, Zhangqun; Sarica, Kemal (Elsevier B.V., 2022)

  Background: Retrograde intrarenal surgery (RIRS) has become the preferred treatment modality for nephrolithiasis. However, because of ongoing uncertainties regarding the optimal perioperative management, operative technique, ...

• Development of mucoadhesive modified kappa-carrageenan/pectin patches for controlled delivery of drug in the buccal cavity 

  Özkahraman, Bengi; Özbaş, Zehra; Yaşayan, Gökçen; Akgüner, Zeynep Püren; Yarımcan, Filiz; Alarçin, Emine; Bal Öztürk, Ayça (Wiley, 2022)

  In this study, modified kappa-carrageenan/pectin hydrogel patches were fabricated for treatment of buccal fungal infections. For this purpose, kappa-carrageenan-g-acrylic acid was modified with different thiolated agents ...

View more