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Recent Submissions
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Polycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies
(Frontiers Media SA, 2022)Polycystic ovary syndrome (PCOS) is a very common, complex, and heterogeneous endocrine disorder of women that involves a combination of environmental and genetic factors. PCOS affects women of growing age particularly at ... -
Consensus and diversity in the management of varicocele for male infertility: Results of a global practice survey and comparison with guidelines and recommendations
(Korean Society for Sexual Medicine and Andrology, 2022)Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, ... -
Spatial association of environmental and dietary factors with copd deaths
(Dove Medical Press Ltd, 2022)Introduction: Chronic obstructive pulmonary disease (COPD) remains a significant health concern globally and spatiotemporal investigations on the etiology and progression of COPD are needed to develop more effective and ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
COVID-19 vaccination and the rate of immune and autoimmune adverse events following immunization: Insights from a narrative literature review
(Frontiers Media S.A., 2022)Despite their proven efficacy and huge contribution to the health of humankind, vaccines continue to be a source of concern for some individuals around the world. Vaccinations against COVID-19 increased the number of ... -
The 13th international. congress on autoimmunity 2022 (AUTO13) Athens: An event as big as the topics
(Israel Medical Association Journal, 2022)The gathering of the 13th International Congress on Autoimmunity 2022 (AUTO13) could not have been held at a place better than the beautiful city of Athens, Greece, at the Megaron Athens International Conference Center ... -
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels (vol 53, 102319, 2022)
(Elsevier, 2022)The authors regret that the cited reference list in the online PDF of this article contains a duplicate reference (Ref 34 and incomplete Ref 56). Ref 56 should read as follows. -
New-onset atrial fibrillation as poor outcome predictor in patients with severe COVID-19
(NLM (Medline), 2022)Tachyarrhythmias are common in patients with coronavirus disease 2019 (COVID-19), in particular those with severe disease. However, newly diagnosed atrial fibrillation (AF) during the course of severe COVID-19 seems to ... -
HIV pre-exposure prophylaxis and its impact on the gut microbiome in men having sex with men
(Frontiers Media S.A., 2022)HIV/AIDS still imposes a high epidemiological and societal burden. Together with antiretroviral therapy, pre-exposure prophylaxis (PrEP) represents a fundamental tool in the fight against HIV/AIDS. PrEP is considered ... -
An efficient approach to access 2,5-disubstituted 1,3,4-oxadiazoles by oxidation of 2-arenoxybenzaldehyde N-acyl hydrazones with molecular iodine
(Wiley-VCH Verlag, 2022)An oxidative cyclization of 2-arenoxybenzaldehyde N-acyl hydrazones 3 a-o was employed to synthesize new 2,5-disubstituted 1,3,4-oxadiazole compounds 4 a-d, 4 f-i, 4 k-n. This method involves oxidative cyclization of ... -
Hedgehog signaling: Linking embryonic lung development and asthmatic airway remodeling
(MDPI, 2022)The development of the embryonic lung demands complex endodermal-mesodermal interactions, which are regulated by a variety of signaling proteins. Hedgehog (Hh) signaling is vital for lung development. It plays a key ... -
Stimuli-responsive theranostic system: A promising approach for augmented multimodal imaging and efficient drug release
(Elsevier B.V., 2022)Destruction of drug resistant and invisible micro-tumors requires innovative screening and treatment modalities. Theranostic nanosystems offering multimodal imaging and therapy are attractive platforms with potential to ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial
(Nature Research, 2022)There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients ... -
Menopause, wellbeing and health: A care pathway from the European Menopause and Andropause Society
(Elsevier Ireland Ltd, 2022)This care pathway from the European Menopause and Andropause Society (EMAS) provides an updated pathway for monitoring and guidance of women at midlife, focusing on those approaching the end of the reproductive lifecycle, ... -
A randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and efficacy of thymoquinone formula (TQF) for treating outpatient SARS-CoV-2
(MDPI, 2022)There is an urgent need for an oral drug for the treatment of mild to moderate outpatient SARS-CoV-2. Our preclinical and clinical study's aim was to determine the safety and preliminary efficacy of oral TQ Formula (TQF), ... -
Turkish validation of the user version of the mobile application rating scale
(AVES, 2022)Objective: As the number of mobile health applications increases, quality assessment becomes a capital feature of any mobile application design. Besides the professional evaluation conducted before marketing the app, the ... -
Lamotrigine derivatives-synthesis, anti-cancer, and anti-MDR-bacterial activities
(Elsevier B.V., 2022)A new series of quaternary ammonium salts 3–21 of lamotrigine (6-(2, 3-dichlorophenyl)-1, 2, 4-triazine-3, 5-diamine) was synthesized via N-alkylation of lamotrigine using different benzyl bromides. The new analogues were ... -
Tumour microenvironment and focal therapy for prostate cancer
(Lippincott Williams & Wilkins, 2022)Purpose of review Although most studies focus on the tumour component of prostate cancer (PCa), increasing attention is being paid to the prostatic tumour microenvironment (TME) and its role in diagnosis, prognosis, and ...