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Sleeping disturbances and predictor risk factors among type 2 diabetic mellitus patients
(Wolters Kluwer Medknow Publications, 2020)Background: Sleep disturbance is a major health issue among people with type 2 diabetes mellitus (T2DM). The Pittsburgh Sleep Quality Index (PSQI) has been the most widely used instrument to measure subjective sleep ... -
Preclinical molecular signatures of spinal cord functional restoration: Optimizing the metamorphic axolotl (ambystoma mexicanum) model in regenerative medicine
(Mary Ann Liebert, 2020)Regenerative medicine offers hope for patients with diseases of the central and peripheral nervous system. Urodele amphibians such as axolotl display an exceptional regenerative capacity and are considered as essential ... -
Concordance of PD-L1 expression and CD8+ TIL intensity between NSCLC and synchronous brain metastases
(2020)Programmed death-ligand 1 (PD-L1) is suggested to be a predictive biomarker in non-small-cell lung carcinoma (NSCLC). However, the differential expression of PD-L1 in primary lung tumor vs. synchronous metastases, especially ... -
Lower prepulse inhibition in clinical high-risk groups but not in familial risk groups for psychosis compared with healthy controls
(Wiley, 2020)Aim: Although the lower level of prepulse inhibition (PPI) of the startle response is well known in schizophrenia, the onset of this difference is not clear. The aim of the present study was to compare PPI in individuals ... -
Relationship between histopathological features of aspirated thrombi and long-term left ventricular function in patients with ST-segment elevation myocardial infarction
(Turkish Society of Cardiology, 2020)Objective: This study was an investigation of the severity ofinflammation (SOI) in aspirated material and thrombus age toexamine any association with pre-discharge and long-term leftventricular (LV) function after ST-elevation ... -
Abnormalities of resting-state EEG in patients with prodromal and overt dementia with Lewy bodies: Relation to clinical symptoms
(Elsevier Ireland Ltd, 2020)Objective: Here we tested if cortical sources of resting state electroencephalographic (rsEEG) rhythms may differ in sub-groups of patients with prodromal and overt dementia with Lewy bodies (DLB) as a function of relevant ... -
Impact of COVID-19 on urology practice: A global perspective and snapshot analysis
(MDPI, 2020)The global impact of the 2019 novel coronavirus disease (COVID-19) pandemic on urology practice remains unknown. Self-selected urologists worldwide completed an online survey by the Societe Internationale d'Urologie (SIU). ... -
Lasers in transurethral enucleation of the prostate-do we really need them
(Multidisciplinary Digital Publishing Institute, 2020)The acronym EEP, coding for transurethral Endoscopic Enucleation of the Prostate, was introduced in 2016 by the European Association of Urology (EAU) guidelines panel on management of non-neurogenic male lower urinary tract ... -
Evaluation of patterns of presentation, practice, and outcomes of upper tract urothelial cancer: protocol for an observational, international, multicenter, cohort study by the clinical research office of the endourology society
(Jmir Publications, 2020)Background: Available guidelines on the management of upper tract urothelial carcinoma (UTUC) are restricted due to the lack of strong evidence-based recommendations. Adequate, well-powered randomized trials are missing ... -
Motoneuron expression profiling identifies an association between an axonal splice variant of HDGF-related protein 3 and peripheral myelination
(American Society for Biochemistry and Molecular Biology Inc, 2020)Disorders that disrupt myelin formation during development or in adulthood, such as multiple sclerosis and peripheral neuropathies, lead to severe pathologies, illustrating myelin's crucial role in normal neural functioning. ... -
Management of adults with suspected foreign body aspiration
(Dicle University, 2021)Objective: Although foreign body aspiration (FBA) in adulthood is not as common as in childhood, it can sometimes be encountered with clinical situations that require urgent interventions. Removal of foreign bodies (FBs) ... -
Comparison of catheter-directed thrombolysis and anticoagulation in intermediate-risk pulmonary embolism: A retrospective analysis
(Wolters Kluwer Medknow Publications, 2021)BACKGROUND AND OBJECTIVES: The selection of escalation of care strategies for the treatment of intermediate-risk pulmonary embolism (PE) is a matter of debate. Here, we aimed to assess the features of our population treated ... -
Severe acute respiratory syndrome coronavirus-2 antigens and antibodies in breast milk
(Istanbul University, 2021)Objective: This study aimed to determine the presence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antigens and IgM and IgG antibodies in breast milk of mothers diagnosed with Coronavirus disease-19 ... -
Does the cardiovascular drug levosimendan prevent iodinated contrast medium nephrotoxicity with glycerol aggravation in rats?
(Springer Nature, 2021)Background We investigated whether levosimendan prevents contrast medium nephrotoxicity with glycerol aggravation in rats. Methods Forty-eight Wistar albino rats were assigned to eight groups (n = 6 x 8). No medication was ... -
Mini percutaneous nephrolithotomy is a noninferior modality to standard percutaneous nephrolithotomy for the management of 20-40 mm renal calculi: A Multicenter randomized controlled trial
(Elsevier, 2021)Background: High quality of evidence comparing mini percutaneous nephrolithotomy (mPNL) with standard percutaneous nephrolithotomy (sPNL) for the treatment of larger-sized renal stones is lacking. Objective: To compare the ... -
Cerebral proliferative angiopathy accompanied by cerebral cavernous malformation: A case report
(Elsevier B. V., 2021)Cerebral Proliferative Angiopathy (CPA) is a rare vascular malformation that is distinguished from classical brain arteriovenous malformations (AVM) in its imaging findings and clinical progression but more importantly in ... -
Poloxamer-188 and d-α-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles integrated orodispersible sublingual films to improve oral bioavailability of ebastine in vitro and in vivo characterization
(MDPI, 2021)Orodispersible sublingual films (OSFs) composed of hydrophilic polymers were loaded with poloxamer-188 and d-alpha-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles to improve the oral bioavailability of ... -
COVID-19 pandemic and psychological fatigue in Turkey
(SAGE Publications Ltd, 2021)Aim: The aim of this study was to investigate the association between the COVID-19 pandemic and psychological fatigue as a mental health issue among the population of Istanbul, Turkey. Participants and methods: This is ... -
A co-culture-based multiparametric imaging technique to dissect local H2O2 signals with targeted HyPer7
(MDPI, 2021)Multispectral live-cell imaging is an informative approach that permits detecting biological processes simultaneously in the spatial and temporal domain by exploiting spectrally distinct biosensors. However, the combination ... -
A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
(Nature Research, 2021)Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ...