Yayıncı "Nature Publishing Group" Makale Koleksiyonu için listeleme
Toplam kayıt 13, listelenen: 1-13
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Calculation of the Ki67 index in pancreatic neuroendocrine tumors: A comparative analysis of four counting methodologies
(Nature Publishing Group, 2015)Ki67 index is now an essential part of classification of pancreatic neuroendocrine tumors. However, its adaptation into daily practice has been fraught with challenges related to counting methodology. In this study, three ... -
Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition
(Nature Publishing Group, 2015)Although cellular prion protein (PrPc) has been suggested to have physiological roles in neurogenesis and angiogenesis, the pathophysiological relevance of both processes remain unknown. To elucidate the role of PrPc in ... -
Dual effects of testosterone in Behcet's disease: Implications for a role in disease pathogenesis
(Nature Publishing Group, 2016)Behcet's disease (BD) exhibits more severe disease course and higher mortality among male patients. However, underlying mechanisms of gender differences in clinical manifestations and disease severity are unclear. The aim ... -
Evaluation of parameters for high efficiency transformation of acinetobacter baumannii
(Nature Publishing Group, 2016)Acinetobacter baumannii is an emerging, nosocomial pathogen that is poorly characterized due to a paucity of genetic tools and methods. While whole genome sequence data from several epidemic and environmental strains have ... -
Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota
(Nature Publishing Group, 2018)Axolotl (Ambystoma mexicanum) is a critically endangered salamander species and a model organism for regenerative and developmental biology. Despite life-long neoteny in nature and in captive-bred colonies, metamorphosis ... -
A genetically specified connectomics approach applied to long-range feeding regulatory circuits
(Nature Publishing Group, 2014)Synaptic connectivity and molecular composition provide a blueprint for information processing in neural circuits. Detailed structural analysis of neural circuits requires nanometer resolution, which can be obtained with ... -
Induced tamoxifen resistance is mediated by increased methylation of e-cadherin in estrogen receptor-expressing breast cancer cells
(Nature Publishing Group, 2019)Estrogen receptor-positive breast cancers are treated with tamoxifen, a drug that competitively inhibits the binding of estrogen to its receptor. Resistance to tamoxifen is a major hurdle in effective management of target ... -
Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
(Nature Publishing Group, 2019)The circadian rhythm is driven by a master clock within the suprachiasmatic nucleus which regulates the rhythmic secretion of melatonin. Bmal1 coordinates the rhythmic expression of transcriptome and regulates biological ... -
Origin and spread of human mitochondrial DNA haplogroup U7
(Nature Publishing Group, 2017)Human mitochondrial DNA haplogroup U is among the initial maternal founders in Southwest Asia and Europe and one that best indicates matrilineal genetic continuity between late Pleistocene huntergatherer groups and present-day ... -
Primate vaginal microbiomes exhibit species specificity without universal Lactobacillus dominance
(Nature Publishing Group, 2014)Bacterial communities colonizing the reproductive tracts of primates (including humans) impact the health, survival and fitness of the host, and thereby the evolution of the host species. Despite their importance, we ... -
Sheehan syndrome
(Nature Publishing Group, 2016)Sheehan syndrome or postpartum hypopituitarism is a condition characterized by hypopituitarism due to necrosis of the pituitary gland. The initial insult is caused by massive postpartum haemorrhage (PPH), leading to impaired ... -
Vasectomy with vessel sealing device: Comparison of different diameters
(Nature Publishing Group, 2019)Objectives Vasectomy is a popular and effective male surgical contraceptive method. Different techniques have been proposed to reduce failure rates and complications. In this study, we sought to compare vas deferens occlusion ... -
White LED light exposure inhibits the development and xanthophore pigmentation of zebrafish embryo
(Nature Publishing Group, 2019)Circadian rhythm in all living organisms is disturbed continuously by artificial light sources and artificial lighting has become a hazard for public health. Circadian rhythm of melatonin maintains high levels of melatonin ...