• The relationship between alexithymia and clinical features in rhinoplasty patients 

  Gökçe Kütük, Sinem; Taşdelen, Yasin; Topuz, Muhammed Fatih; Bilece, Zeki Tolga; Düzenli, Ufuk; Bora, Fatih (Elsevier Science Ltd, 2022)

  Summary Objective: The present study aimed to investigate the incidence of alexithymia in rhinoplasty patients before and after surgery, and to increase the value of alexithymia analysis. The study also aimed to evaluate ...

• The relationship between elevated plasma zonulin levels and hashimoto's thyroiditis 

  Demir, Esra; Önal, Burak; Özkan, Hanise; Kıraç Utku, İrem; Sahtiyancı, Berrak; Kumbasar, Abdulbaki; Yenmiş, Güven; Demir, Bülent (Tubitak Scientific and Technical Research Council Turkey, 2022)

  Background/aim: Hashimoto thyroiditis (HT) is one of the most prevalent autoimmune diseases. The intestine microbiota is strongly associated with autoimmune diseases. Zonulin, a modulator of tight junctions that controls ...

• First-line usage of daratumumab, lenalidomide, dexamethasone (DRd) combination in a case of castleman disease variant of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome (CD-POEMS) 

  Sevindik, Ömür Gökmen; Mutlu, Yaşa Gül; Balık Aydın, Berrin; Serin, İstemi (Lippincot Williams & Wilkins, 2022)

  Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome (POEMS) is a rare paraneoplastic syndrome of an underlying plasma cell disorder (PCD).1 Castleman disease (CD), itself, can ...

• Medical residents are facing burnout, who are at stake? A cross- sectional study in three university hospitals in Istanbul 

  Küçükali, Hüseyin; Hayran, Osman; Ankaralı, Zeynep Cemile; Cengiz, Canan; Karakaya, Ravza Nur; Yüce, Fatıma Zehra (Dokuz Eylül University Institute of Health Sciences, 2022)

  Introduction: Residency has become a vulnerable period for burnout among physicians because many common and specific stress factors in healthcare. Our study aims to evaluate the burnout level among medical residents in ...

• The effectiveness and tolerability of clobazam in the pediatric population: Adjunctive therapy and monotherapy in a large-cohort multicenter study 

  Kamaşak, Tülay; Serdaroğlu, Esra; Yılmaz, Özlem; Aydın Kılıç, Betül; Gönüllü Polat, Burçin; Erdoğan, Irmak; Yücel Şen, A. Derda; Özen, Nalan; Durgut, Betül Diler; Yıldız, Nihal; Özkan Kart, Pınar; Dilber, Beril; Acar Arslan, Elif; Şahin, Sevim; Topçu, Yasemin; Gençpınar, Pınar; Serin, ‪Hepsen Mine; Hız, Semra A.; Çarman, Kürşat Bora; Olgaç Dündar, Nihal; Okuyaz, Çetin; Aydın, Kürşad; Serdaroğlu, Ayşe; Tekgül, Hasan; Cansu, Ali (Elsevier B.V., 2022)

  Objective: To evaluate the effectiveness and tolerability of clobazam therapy in the pediatric population in terms of seizure semiology, epileptic syndromes, and etiological subgroups. Methods: A retrospective cohort study ...

• Further clinical and genetic evidence of ASC-1 complex dysfunction in congenital neuromuscular disease 

  Marais, Anett; Bertoli-Avella, Aida M.; Beetz, Christian; Altunoğlu, Umut; Alhashem, Amal; Mohamed, Sarar; Alghamdi, Abdulaziz; Willems, Patrick; Tsoutsou, Eirini; Fryssira, Helena; Pons, Roser; Almarzooq, Reem; Yüksel Karatoprak, Elif; Ayaz, Akif; Ünverengil, Gökçen; Calvo, Maria; Yüksel, Zafer; Bauer, Peter (Elsevier Masson s.r.l., 2022)

  Transcriptional coregulators modulate the efficiency of transcription factors. Bi-allelic variants in TRIP4 and ASCC1, two genes that encode members of the tetrameric coregulator ASC-1, have recently been associated with ...

• The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer 

  Comba, Cihan; Özdemir, İsa Aykut; Demirayak, Gökhan; Erdoğan, Şakir Volkan; Demir, Ömer; Yıldız, Güneş Özlem; Bulut, Huri; Karakaş, Sema; Gülseren, Varol; Afşar, Selim; Güngördük, Kemal (Elsevier Ltd, 2022)

  Objective: To investigate the blood levels of adipokines in obese patients with endometrial cancer who have and have not undergone omentectomy. Methods: Between September 2017 and September 2019, the study recruited 54 ...

• Contrast-induced nephropathy in Covid 19 patients undergoing emergency percutaneous coronary intervention 

  Demirçelik, Bora; Özcan, Özgür Ulaş; Yazar, Arzu; Savur, Ümeyir; Güler, Yeliz; Hakgör, Aykun; Boztosun, Bilal (A. CARBONE Editore, 2022)

  Background: Covid 19 is an infectious disease, which leads to many adverse effects, such as hypercoagulopathy. Since, the number of the emergency percutaneous coronary intervention (PCI) has increased due to this effect ...

• Beta-sitosterol and its antinociceptive mechanism action 

  Şakul, Ayşe Arzu; Okur, Mehmet Evren (Ankara University, 2022)

  Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to ...

• Diagnostic and prognostic value of Nesfatin-1 in sepsis and septic shock 

  Toprak, İlkim Deniz; Eruzun, Hasan; Kutlu, Yasin; Arman, Yücel; Yumuştutan, Pembegül; Aydın Yoldemir, Şengül; Akarsu, Murat; Dikker, Okan; Tükek, Tufan (Ondokuz Mayis University, 2022)

  Nesfatin-1 is an anorectic protein, and we expect it to decrease during sepsis and septic shock. We aimed to analyze it and determine the relationship between Nesfatin-1 levels and quick Sequential Organ Failure Assessment(qSOFA) ...

• The comparison of Ottawa Ankle Rules and Shetty test performances in foot-ankle trauma patients visited to the emergency department 

  Ak, Rohat; Kurt, Erdem; Bahadırlı, Suphi; Çakır, Mehmet Semih; Bilgu, Ali Selman; Eke Kurt, Şebnem Zeynep (Elsevier Science Ltd, 2022)

  Background: The Ottawa Ankle Rules (OARs) and Shetty test (ST), are assessment guidelines intended to minimize radiographs in patients with ankle trauma. The aim of this study is to determine and compare the effectiveness ...

• In vivo generated autologous plasmin assisted vitrectomy in young patients 

  Aras, Cengiz; Şentürk, Fevzi; Koytak, Arif; Doğramacı, Mahmut; Karaman Erdur, Sevil; Kocabora, Selim (BioMed Central Ltd, 2022)

  Background Autologous plasmin enzyme facilitates the induction of posterior vitreous detachment(PVD) during vitrectomy in young patients. We proposed the concept of in-vivo generated plasmin which is based on the injection ...

• Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells 

  Uludağ, Damla; Bay, Sadık; Onur Sucu, Bilgesu; Şavluğ İpek, Özgecan; Mohr, Thomas; Güzel, Mustafa; Karakaş, Nihal (Frontiers Media S.A., 2022)

  Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ...

• Oxidative stress in maternal milk and cord blood in gestational diabetes mellitus: A prospective study 

  Erdoğan, Fırat; Şenkal, Evrim; Özer, Ömer Faruk; İpek, İlke Özahi; Altuntaş, Şükriye Leyla; Özde, Şükriye (Associacao Paulista Medicina, 2022)

  BACKGROUND: Reduced antioxidant defenses may reflect a poor protective response against oxidative stress and this may be implicated in progression of gestational diabetes mellitus (GDM). Oxidative stress induced by ...

• Stress-induced Childhood Onset Neurodegeneration with Ataxia and Seizures (CONDSIAS) presenting with torticollis attacks: Phenotypic variability of the same mutation in two Turkish patients 

  Öztürk, Gülten; Ayaz, Akif; Topçu, Yasemin; Akyüz, Gülcan; Ünver, Olcay; Akbeyaz, İsmail; Ekinci, Gazanfer; Türkdoğan, Dilşad (Wolters Kluwer Medknow Publications, 2022)

  Two patients with the same genetic mutation in ADPRHL2 gene, which takes a role in DNA repair, transcription, telomer function, and apoptosis are presented.[1] Developmental delay, intellectual disability, epilepsy, ...

• Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease 

  Yener, Görsev; Hünerli Gündüz, Duygu; Yıldırım, Ebru; Aktürk, Tuba; Başar Eroğlu, Canan; Bonanni, Laura; Del Percio, Claudio; Farina, Francesca; Ferri, Raffaele; Güntekin, Bahar; Hajós, Mihály; Ibáñez, Agustín; Jiang, Yang; Lizio, Roberta; Lopez, Susanna; Noce, Giuseppe; Parra, Mario A.; Randall, Fiona; Stocchi, Fabrizio; Babiloni, Claudio (Elsevier B.V., 2022)

  Alzheimer's disease dementia (ADD) is the most diffuse neurodegenerative disorder belonging to mild cognitive impairment (MCI) and dementia in old persons. This disease is provoked by an abnormal accumulation of amyloid-beta ...

• Predicting the effects of repetitive transcranial magnetic stimulation on cognitive functions in patients with alzheimer's disease by automated EEG analysis 

  Kayasandık, Cihan Bilge; Velioğlu, Halil Aziz; Hanoğlu, Lütfü (Frontiers Media SA, 2022)

  Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that generally affects the elderly. Today, after the limited benefit of the pharmacological treatment strategies, numerous noninvasive brain ...

• Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial 

  Hajebrahimi, Farzin; Velioğlu, Halil Aziz; Bayraktaroğlu, Zübeyir; Helvacı Yılmaz, Nesrin; Hanoğlu, Lütfü (Nature Research, 2022)

  There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients ...

• Editorial: The role of vitamin D in gut health and disease in children 

  Day, Andrew S.; Bener, Abdulbari; Tewfik, Ihab; Vajro, Pietro; Zughaier, Susu M. (Frontiers Media SA, 2022)

  The metabolism of vitamin D relies predominantly upon the synthesis of cholecalciferol (vitamin D3) in the epidermis following exposure to sunlight (specifically ultraviolet B rays) and the subsequent hydroxylation to ...

• Interacting with AP1 complex mutated synergin gamma (SYNRG) reveals a novel coatopathy in the form of complicated hereditary spastic paraplegia 

  Ayaz, Akif; Aksu Uzunhan, Tuğçe; Aydın, Kürşad (Elsevier, 2022)

  Background: Today, it is known that about 80 genes are involved in the etiology of hereditary spastic paraplegia. However, there are many cases whose etiology could not be determined by extensive genetic tests such as ...

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