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Recent Submissions
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The relationship between alexithymia and clinical features in rhinoplasty patients
(Elsevier Science Ltd, 2022)Summary Objective: The present study aimed to investigate the incidence of alexithymia in rhinoplasty patients before and after surgery, and to increase the value of alexithymia analysis. The study also aimed to evaluate ... -
The relationship between elevated plasma zonulin levels and hashimoto's thyroiditis
(Tubitak Scientific and Technical Research Council Turkey, 2022)Background/aim: Hashimoto thyroiditis (HT) is one of the most prevalent autoimmune diseases. The intestine microbiota is strongly associated with autoimmune diseases. Zonulin, a modulator of tight junctions that controls ... -
First-line usage of daratumumab, lenalidomide, dexamethasone (DRd) combination in a case of castleman disease variant of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome (CD-POEMS)
(Lippincot Williams & Wilkins, 2022)Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome (POEMS) is a rare paraneoplastic syndrome of an underlying plasma cell disorder (PCD).1 Castleman disease (CD), itself, can ... -
Medical residents are facing burnout, who are at stake? A cross- sectional study in three university hospitals in Istanbul
(Dokuz Eylül University Institute of Health Sciences, 2022)Introduction: Residency has become a vulnerable period for burnout among physicians because many common and specific stress factors in healthcare. Our study aims to evaluate the burnout level among medical residents in ... -
The effectiveness and tolerability of clobazam in the pediatric population: Adjunctive therapy and monotherapy in a large-cohort multicenter study
(Elsevier B.V., 2022)Objective: To evaluate the effectiveness and tolerability of clobazam therapy in the pediatric population in terms of seizure semiology, epileptic syndromes, and etiological subgroups. Methods: A retrospective cohort study ... -
Further clinical and genetic evidence of ASC-1 complex dysfunction in congenital neuromuscular disease
(Elsevier Masson s.r.l., 2022)Transcriptional coregulators modulate the efficiency of transcription factors. Bi-allelic variants in TRIP4 and ASCC1, two genes that encode members of the tetrameric coregulator ASC-1, have recently been associated with ... -
The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer
(Elsevier Ltd, 2022)Objective: To investigate the blood levels of adipokines in obese patients with endometrial cancer who have and have not undergone omentectomy. Methods: Between September 2017 and September 2019, the study recruited 54 ... -
Contrast-induced nephropathy in Covid 19 patients undergoing emergency percutaneous coronary intervention
(A. CARBONE Editore, 2022)Background: Covid 19 is an infectious disease, which leads to many adverse effects, such as hypercoagulopathy. Since, the number of the emergency percutaneous coronary intervention (PCI) has increased due to this effect ... -
Beta-sitosterol and its antinociceptive mechanism action
(Ankara University, 2022)Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to ... -
Diagnostic and prognostic value of Nesfatin-1 in sepsis and septic shock
(Ondokuz Mayis University, 2022)Nesfatin-1 is an anorectic protein, and we expect it to decrease during sepsis and septic shock. We aimed to analyze it and determine the relationship between Nesfatin-1 levels and quick Sequential Organ Failure Assessment(qSOFA) ... -
The comparison of Ottawa Ankle Rules and Shetty test performances in foot-ankle trauma patients visited to the emergency department
(Elsevier Science Ltd, 2022)Background: The Ottawa Ankle Rules (OARs) and Shetty test (ST), are assessment guidelines intended to minimize radiographs in patients with ankle trauma. The aim of this study is to determine and compare the effectiveness ... -
In vivo generated autologous plasmin assisted vitrectomy in young patients
(BioMed Central Ltd, 2022)Background Autologous plasmin enzyme facilitates the induction of posterior vitreous detachment(PVD) during vitrectomy in young patients. We proposed the concept of in-vivo generated plasmin which is based on the injection ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Oxidative stress in maternal milk and cord blood in gestational diabetes mellitus: A prospective study
(Associacao Paulista Medicina, 2022)BACKGROUND: Reduced antioxidant defenses may reflect a poor protective response against oxidative stress and this may be implicated in progression of gestational diabetes mellitus (GDM). Oxidative stress induced by ... -
Stress-induced Childhood Onset Neurodegeneration with Ataxia and Seizures (CONDSIAS) presenting with torticollis attacks: Phenotypic variability of the same mutation in two Turkish patients
(Wolters Kluwer Medknow Publications, 2022)Two patients with the same genetic mutation in ADPRHL2 gene, which takes a role in DNA repair, transcription, telomer function, and apoptosis are presented.[1] Developmental delay, intellectual disability, epilepsy, ... -
Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease
(Elsevier B.V., 2022)Alzheimer's disease dementia (ADD) is the most diffuse neurodegenerative disorder belonging to mild cognitive impairment (MCI) and dementia in old persons. This disease is provoked by an abnormal accumulation of amyloid-beta ... -
Predicting the effects of repetitive transcranial magnetic stimulation on cognitive functions in patients with alzheimer's disease by automated EEG analysis
(Frontiers Media SA, 2022)Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that generally affects the elderly. Today, after the limited benefit of the pharmacological treatment strategies, numerous noninvasive brain ... -
Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial
(Nature Research, 2022)There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients ... -
Editorial: The role of vitamin D in gut health and disease in children
(Frontiers Media SA, 2022)The metabolism of vitamin D relies predominantly upon the synthesis of cholecalciferol (vitamin D3) in the epidermis following exposure to sunlight (specifically ultraviolet B rays) and the subsequent hydroxylation to ... -
Interacting with AP1 complex mutated synergin gamma (SYNRG) reveals a novel coatopathy in the form of complicated hereditary spastic paraplegia
(Elsevier, 2022)Background: Today, it is known that about 80 genes are involved in the etiology of hereditary spastic paraplegia. However, there are many cases whose etiology could not be determined by extensive genetic tests such as ...