Başlık için Uluslararası Tıp Fakültesi listeleme
Toplam kayıt 531, listelenen: 128-147
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Determination of antioxidant, anticancer, antidiabetic and antimicrobial activities of Turkish red pine (Pinus brutia Ten.) bark ultrasound-assisted extract as a functional food additive
(Akademiai Kiado Zrt., 2023)Turkish red pine (Pinus brutia Ten.) is an important tree species that grows widely in Turkiye. In this study, Box-Behnken experimental design was created and optimised for ultrasound assisted extraction of bioactive ... -
Determination of beck depression inventory scores of the patients in a hemodialysis center: Evaluation with a holistic approach
(2020)Aim/ Background: The holistic approach in medicine refers to addressing an individual as a whole. Family physicians should be familiar with psychological as well as physical problems of their hemodialysis patients. This ... -
Development of a chemogenetic approach to manipulate intracellular pH
(American Chemical Society, 2023)Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ... -
Development of automated analysis of biomedical signals obtained from calcium imaging
(Springer, 2019)... -
Development of light and pH-dual responsive self-quenching theranostic SPION to make EGFR overexpressing micro tumors glow and destroy
(Elsevier B.V., 2023)Drug resistant and undetectable tumors easily escape treatment leading metastases and/or recurrence of the lethal disease. Therefore, it is vital to diagnose and destroy micro tumors using simple yet novel approaches. Here, ... -
Development of mucoadhesive modified kappa-carrageenan/pectin patches for controlled delivery of drug in the buccal cavity
(Wiley, 2022)In this study, modified kappa-carrageenan/pectin hydrogel patches were fabricated for treatment of buccal fungal infections. For this purpose, kappa-carrageenan-g-acrylic acid was modified with different thiolated agents ... -
Development of the most comprehensive genetic test based on next generation sequencing for diagnosis of congenital hypothyroidism
(Nature Publishing Group, 2018)... -
The difference of mild cognitive impairment in Parkinson's disease from amnestic mild cognitive impairment: Deeper power decrement and no phase-locking in visual event-related responses
(Elsevier Science Bv, 2019)Event-related oscillatory responses reflect the cognitive status in many neuropsychiatric conditions including mild cognitive impairment (MCI). In this study, a total of 30 patients with amnestic MCI (aMCI) and 25 patients ... -
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
(Wolters Kluwer, 2019)It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ... -
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
(Czech Medical Soc, 2019)Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ... -
Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease
(Wiley, 2023)The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ... -
Diffusion-based hierarchical multi-label object detection to analyze panoramic dental X-rays
(Springer Science and Business Media Deutschland GmbH, 2023)Due to the necessity for precise treatment planning, the use of panoramic X-rays to identify different dental diseases has tremendously increased. Although numerous ML models have been developed for the interpretation of ... -
Digenic DUOX1 and DUOX2 mutations in cases with congenital hypothyroidism
(Oxford University Press Inc, 2017)Context: The DUOX2 enzyme generates hydrogen peroxide (H2O2), a crucial electron acceptor for the thyroid peroxidase-catalyzed iodination and coupling reactions mediating thyroid hormone biosynthesis. DUOX2 mutations result ... -
Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice
(Nature Research, 2022)Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian rhythm and the relation of such a decrease ... -
Distal femur morphology and the suitability of standard guides for knee arthroplasty in the Turkish population
(2024)Objective: The aim of this study was to evaluate the posterior condylar angle (PCA) and condylar twist angle (CTA) of the distal femur in the Turkish population and its concordance with the current standard prosthesis ... -
DNA methylation pattern of TM6SF2 influences NAFLD progression in genotype-dependent manner
(Elsevier Science Bv, 2019)Background and aims: Non-alcoholic fatty liver disease (NAFLD) arises due to complex interaction of genetic and environmental factors. Evidence suggests that transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is ... -
Does a microfluidic chip for sperm sorting have a positive add-on effect on laboratory and clinical outcomes of intracytoplasmic sperm injection cycles? A sibling oocyte study
(Wiley, 2019)The most recent technologies for sperm sorting involve microfluidics. However, the most important question whether their use is of any advantage in terms of laboratory and clinical IVF/ICSI outcomes still remains controversy. ... -
Does Ramadan fasting have effects on sleep, fatigue and blood pressure among patients with hypertension?
(NLM (Medline), 2021)AIM: The aim of this study was to determine the effect of Ramadan fasting on blood pressure (BP), fatigue, sleeping and physical activity among hypertensive patients. SUBJECTS AND METHODS: A cross-sectional study was ... -
Does the cardiovascular drug levosimendan prevent iodinated contrast medium nephrotoxicity with glycerol aggravation in rats?
(Springer Nature, 2021)Background We investigated whether levosimendan prevents contrast medium nephrotoxicity with glycerol aggravation in rats. Methods Forty-eight Wistar albino rats were assigned to eight groups (n = 6 x 8). No medication was ...