The effect of chamomile extract on blood sugar level, lipid profile and body weight in high-fat diet fed rats

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dc.authorid0000-0003-0217-0938
dc.authorid0000-0003-1420-0989
dc.authorid0000-0001-8241-647X
dc.contributor.authorBarcın Güzeldere, Hatice Kübra
dc.contributor.authorBüyükuslu, Nihal
dc.contributor.authorİduğ, Tuğba
dc.date.accessioned2022-06-06T09:09:26Z
dc.date.available2022-06-06T09:09:26Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractThe addition of herbs to the diet is one of the methods for the treatment of obesity. It is aimed to examine the extracts of chamomile to use in the treatment of obesity, against high-fat diet. In this study, 6-8 weeks old fifteen female Sprague-Dawley rats were used. Five of the rats separated randomly for the control group and fed with a standard pellet for ten weeks. Ten rats were fed with a high-fat diet for four weeks. After this period, the rats were randomly divided into two groups (high-fat control and chamomile). Blood samples were taken for lipid profiles and glucose. With the high-fat diet, body weights and total cholesterol had increased significantly (p<0.05). Chamomile had a 39.2% decrease in body weight and a 38.8% decrease in blood glucose (p<0.05). There was no difference between groups in other lipid parameters. Chamomile may be used in the treatment of obesity.
dc.identifier.citationBarcın Güzeldere, H. K., Büyükuslu, N. ve İduğ, T. (2022). The effect of chamomile extract on blood sugar level, lipid profile and body weight in high-fat diet fed rats. Acta Pharmaceutica Sciencia, 60(2), 203-212. https://doi.org/10.23893/1307-2080.APS.6014
dc.identifier.doi10.23893/1307-2080.APS.6014
dc.identifier.endpage212
dc.identifier.issn1307-2080
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85130204151
dc.identifier.scopusqualityQ3
dc.identifier.startpage203
dc.identifier.urihttps://doi.org/10.23893/1307-2080.APS.6014
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9507
dc.identifier.volume60
dc.indekslendigikaynakScopus
dc.institutionauthorBarcın Güzeldere, Hatice Kübra
dc.institutionauthorBüyükuslu, Nihal
dc.institutionauthorİduğ, Tuğba
dc.language.isoen
dc.publisherIstanbul Medipol University
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectChamomile
dc.subjectHigh-Fat Diet
dc.subjectObesity
dc.subjectWeight Loss
dc.titleThe effect of chamomile extract on blood sugar level, lipid profile and body weight in high-fat diet fed rats
dc.typeArticle

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