Is implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation?

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dc.authorid0000-0003-2003-6337
dc.authorid0000-0002-8084-7855
dc.contributor.authorKaraarslan, Numan
dc.contributor.authorYılmaz, İbrahim
dc.contributor.authorÖzbek, Hanefi
dc.contributor.authorÖznam, Kadir
dc.contributor.authorAteş, Özkan
dc.contributor.authorErdem, İlknur
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:04:11Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:04:11Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı
dc.descriptionWOS: 000450653000008
dc.descriptionPubMed ID: 29368319
dc.description.abstractAIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant infections. MATERIAL and METHODS: A total of 166 consecutive lumbar stenosis and spondylolisthesis patients undergoing lumbar instrumentation between 2012 and 2016 were analyzed retrospectively. The patients were divided into two groups. Group I (n=85) included patients whose implants were washed with rifampicin immediately before insertion and whose surgical fields were irrigated with diluted rifampicin immediately after insertion. Group II (n=81) included the cases without rifampicin application. Both groups were matched for age, sex, body mass index, and surgical indication. The infection rates of the groups were compared during the first 2 postoperative years. RESULTS: No significant difference was found between the infection rate in Group I and Group II. Only 1 case had surgical site infection (SSI) in Group I, a rate of 1.17% (1 of 85 patients), whereas 2 patients had SSI in Group II, a rate of 2.46% (2 of 81 patients). CONCLUSION: Peroperative washing of implants with rifampicin and irrigation of the surgical field using diluted rifampicin have not been found to be significantly effective in preventing or reducing spinal implant infections. However, further studies with larger series need to be carried out to verify these results.
dc.identifier.citationKaraarslan, N., Yılmaz, İ., Özbek, H., Öznam, K., Ateş, Ö. ve Erdem, İ. (2018). Is implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation? Journal of Turkish Neurosurgery, 28(6), 904-909. https://dx.doi.org/10.5137/1019-5149.JTN.21341-17.2
dc.identifier.doi10.5137/1019-5149.JTN.21341-17.2
dc.identifier.endpage909
dc.identifier.issn1019-5149
dc.identifier.issue6
dc.identifier.scopusqualityQ3
dc.identifier.startpage904
dc.identifier.urihttps://dx.doi.org/10.5137/1019-5149.JTN.21341-17.2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4011
dc.identifier.volume28
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Neurosurgical Society
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectImplant
dc.subjectInfection Rate
dc.subjectIrrigation
dc.subjectSpine
dc.subjectRifampicin
dc.titleIs implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation?
dc.typeArticle

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