Assessment of developmental neurotoxicity using semi-automatic behavior analysis system for zebrafish

Basit Öğe Kaydı
dc.authorid0000-0002-6274-801X
dc.contributor.authorCansız, Derya
dc.contributor.authorÜnal, İsmail
dc.contributor.authorBeler, Merih
dc.contributor.authorAlturfan, Ahmet Ata
dc.contributor.authorEmekli Alturfan, Ebru
dc.date.accessioned2024-02-20T08:16:35Z
dc.date.available2024-02-20T08:16:35Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractTraditionally, morphological, conventional, and toxicological approaches have been used to demonstrate neurotoxicity; however, there has been a growing interest in animal behavioral methods for assessing neurotoxicity, both at the scientific and regulatory levels. Zebrafish (Danio rerio) is a small tropical freshwater fish currently recognized as a suitable model organism for investigating developmental neurotoxicity. There are many animal-tracking software programms used for behavioral analysis in biomedical research. Some of these software programms require a fee, which may exceed the laboratory budget and require detailed technical equipment. As a solution, freely available programs can be used. However, animal tracking may not be possible due to the glare from the aquatic environment of fish, and the small size of zebrafish embryos makes animal tracking difficult. In our laboratory, we developed a semi-automatic system to overcome these difficulties by using three different software available for free. This chapter explains the system for zebrafish embryos and adult zebrafish.
dc.identifier.citationCansız, D., Ünal, İ., Beler, M., Alturfan, A. A. ve Emekli Alturfan, E. (2024). Assessment of developmental neurotoxicity using semi-automatic behavior analysis system for zebrafish. Methods in Molecular Biology içinde (409-419. ss.). Humana Press Inc. https://dx.doi.org/10.1007/978-1-0716-3625-1_25
dc.identifier.doi10.1007/978-1-0716-3625-1_25
dc.identifier.endpage419
dc.identifier.issn1064-3745
dc.identifier.issn1940-6029
dc.identifier.pmid38285356
dc.identifier.scopus2-s2.0-85184344806
dc.identifier.scopusqualityQ3
dc.identifier.startpage409
dc.identifier.urihttps://dx.doi.org/10.1007/978-1-0716-3625-1_25
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12289
dc.identifier.volume2753
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorCansız, Derya
dc.language.isoen
dc.publisherHumana Press Inc.
dc.relation.ispartofMethods in Molecular Biologyen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBehaviour Analysis
dc.subjectSemi-Automatic System
dc.subjectZebrafish
dc.subjectZebrafish Embryos
dc.titleAssessment of developmental neurotoxicity using semi-automatic behavior analysis system for zebrafish
dc.typeBook Chapter

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Kitap Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu