Parkinson's disease and the COVID-19 pandemic: Do quarantine affect the motor and non-motor symptoms of patients with and without deep brain stimulation?

Helvacı Yılmaz, Nesrin; Bolluk Kılıç, Başak; Zırh, Tahsin Ali; Aslan, Asile Seval; Hanoğlu, Lütfü

Parkinson's disease and the COVID-19 pandemic: Do quarantine affect the motor and non-motor symptoms of patients with and without deep brain stimulation?

dc.authorid	0000-0001-7566-1063
dc.authorid	0000-0002-7712-738X
dc.authorid	0000-0002-8811-2263
dc.authorid	0000-0002-2761-0031
dc.authorid	0000-0003-4292-5717
dc.contributor.author	Helvacı Yılmaz, Nesrin
dc.contributor.author	Bolluk Kılıç, Başak
dc.contributor.author	Zırh, Tahsin Ali
dc.contributor.author	Aslan, Asile Seval
dc.contributor.author	Hanoğlu, Lütfü
dc.date.accessioned	2022-07-21T09:31:24Z
dc.date.available	2022-07-21T09:31:24Z
dc.date.issued	2022
dc.department	İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.department	İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.description.abstract	Aim: Patients with chronic diseases were forced into lockdown due to the coronavirus disease-2019 pandemic. Extended quarantine could lead to physical inactivity and psychiatric problems. We investigated the effects of quarantine and social isolation during the pandemic on the motor and non-motor symptoms (NMS) of Parkinson's disease (PD) patients with and without deep brain stimulation (DBS). Methods: This study included 168 patients with PD who were in quarantine for 2 months (between April 1, 2020 and May 31, 2020). Eighty-three patients had undergone bilateral subthalamic DBS surgery. A questionnaire with three parts was administered via phone: 1) motor symptoms, 2) NMS, and 3) the reasons for impairment. Results: Of the patients, 54.7% reported impairment in at least one motor symptom and 58.9% reported impairment in at least one NMS. Increased tremors, difficulty with turning in bed, and insomnia were significantly more pronounced in patients without DBS. Patients with DBS complained less of being bored due to staying at home and had less deterioration due to lack of exercise and slower disease progression. Conclusion: Half of the symptoms of patients with PD worsened during quarantine, but patients with DBS tolerated the lockdown better. Telemedicine and online physiotherapy programs should be recommended to prevent rapid disease progression.
dc.identifier.citation	Helvacı Yılmaz, N., Bolluk Kılıç, B., Zırh, T. A., Aslan, A. S. ve Hanoğlu, L. (2022). Parkinson's disease and the COVID-19 pandemic: Do quarantine affect the motor and non-motor symptoms of patients with and without deep brain stimulation? The Medical Bulletin of Haseki, 60(3), 204-210. http://doi.org/10.4274/haseki.galenos.2022.8225
dc.identifier.doi	10.4274/haseki.galenos.2022.8225
dc.identifier.endpage	210
dc.identifier.issn	1302-0072
dc.identifier.issn	2147-2688
dc.identifier.issue	3
dc.identifier.scopus	2-s2.0-85133833708
dc.identifier.scopusquality	Q4
dc.identifier.startpage	204
dc.identifier.uri	http://doi.org/10.4274/haseki.galenos.2022.8225
dc.identifier.uri	https://hdl.handle.net/20.500.12511/9590
dc.identifier.volume	60
dc.identifier.wos	000823150600003	en_US
dc.identifier.wosquality	N/A
dc.indekslendigikaynak	Web of Science
dc.indekslendigikaynak	Scopus
dc.indekslendigikaynak	TR-Dizin
dc.institutionauthor	Helvacı Yılmaz, Nesrin
dc.institutionauthor	Bolluk Kılıç, Başak
dc.institutionauthor	Zırh, Tahsin Ali
dc.institutionauthor	Aslan, Asile Seval
dc.institutionauthor	Hanoğlu, Lütfü
dc.language.iso	en
dc.publisher	Galenos Publishing
dc.relation.ispartof	The Medical Bulletin of Haseki	en_US
dc.relation.publicationcategory	Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	COVID-19
dc.subject	Deep Brain Stimulation
dc.subject	Parkinson’s Disease
dc.subject	Quarantine
dc.title	Parkinson's disease and the COVID-19 pandemic: Do quarantine affect the motor and non-motor symptoms of patients with and without deep brain stimulation?
dc.type	Article