Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities

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dc.contributor.authorTay, Naime Funda
dc.contributor.authorYurttaş, Leyla
dc.contributor.authorDemirayak, Şeref
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:58:05Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:58:05Z
dc.date.issued2012
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalı
dc.descriptionWOS: 000306524200007
dc.descriptionPubMed ID: 21823837
dc.description.abstractIn this study, some N-[4-(Benzothiazole-2-yl)phenyl]-2-aryloxyacetamide derivatives were prepared by reacting N-[4-(benzothiazole-2yl)phenyl]-2-chloroacetamide and different substituent phenol or thiophenol derivatives. The anticancer activities of the compounds obtained were investigated. It was observed that some of the compounds, namely 25 and 38, showed notable anticancer activity.
dc.description.sponsorshipEskisehir Osmangazi University [ESOGU/200819010]en_US
dc.description.sponsorshipThis work was supported by the Commission of Scientific Research Projects of Eskisehir Osmangazi University (ESOGU/200819010). The authors gratefully acknowledge the financial support by Eskisehir Osmangazi University. Authors also would like to thank to National Cancer Institue (NCI), Bethesda, MD, USA for in vitro screening of our compounds in human cancer cell lines.en_US
dc.description.sponsorshipEskisehir Osmangazi Universityen_US
dc.identifier.citationTay, N. F., Yurttaş, L. ve Demirayak, Ş. (2012). Synthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities. Journal of Enzyme of Inhıbıtıon and Medıcınal Chemıstry, 27(4), 515-520. https://dx.doi.org/10.3109/14756366.2011.599030
dc.identifier.doi10.3109/14756366.2011.599030
dc.identifier.endpage520
dc.identifier.issn1475-6366
dc.identifier.issue4
dc.identifier.scopusqualityQ2
dc.identifier.startpage515
dc.identifier.urihttps://dx.doi.org/10.3109/14756366.2011.599030
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3105
dc.identifier.volume27
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInforma Healtcare
dc.relation.ispartofJournal of Enzyme Inhibition and Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBenzothiazole
dc.subjectAntitumour
dc.subjectNon-small Cell Lung Cancer
dc.subjectProstate Cancer
dc.titleSynthesis of some N-[4-(benzothiazole-2yl)phenyl]-2-aryloxyacetamide derivatives and their anticancer activities
dc.typeArticle

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