The corneal effects of intravitreal dexamethasone implantation
| dc.authorid | 0000-0003-1827-968X | |
| dc.contributor.author | Bayat, Alper Halil | |
| dc.contributor.author | Karataş, Gamze | |
| dc.contributor.author | Kurt, Muhammet Mustafa | |
| dc.contributor.author | Elçioğlu, Mustafa Nuri | |
| dc.date.accessioned | 2020-09-03T06:38:05Z | |
| dc.date.available | 2020-09-03T06:38:05Z | |
| dc.date.issued | 2020 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı | |
| dc.description.abstract | Objectives: To evaluate the corneal effects of the intravitreal dexamethasone implantation using corneal topography and specular microscopy.Material and methods: 27 eyes of the 27 patients who received a single intravitreal dexamethasone implantation dose for diabetic macular edema were enrolled in this study. Sirius topography and EM-3000 specular microscopic examinations were performed at the initial examination (baseline), and then on the first day, during the first week, and 1 month after IDI. Changes in corneal parameters were investigated.Results: The mean age was 58.66 +/- 6.59 years. 15 patients were men, and 12 were women. The mean disease duration was 12.2 +/- 2.4 months, and mean glycosylated hemoglobin (HbA1c) was 7.2 +/- 1.1. After dexamethasone injection, the mean central corneal thickness, endothelial cell density, and coefficient variation of cell area presented a statistically significant decrease (p < 0.05). Anterior segment parameters, such as anterior chamber depth, iridocorneal angle, sim K1 and K2 keratometry, pupillary diameter, horizontal visible iris diameter, and corneal astigmatism did not change (p > 0.05).Conclusion: Intravitreal dexamethasone implantation affects corneal endothelial cell structure but does not appear to affect corneal topography parameters. | |
| dc.identifier.citation | Bayat, A. H., Karataş, G., Kurt, M. M. ve Elçioğlu, M. N. (2020). The corneal effects of intravitreal dexamethasone implantation. Therapeutic Advances in Ophthalmology, 12. https://dx.doi.org/10.1177/2515841420947544 | |
| dc.identifier.doi | 10.1177/2515841420947544 | |
| dc.identifier.issn | 2515-8414 | |
| dc.identifier.uri | https://dx.doi.org/10.1177/2515841420947544 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/5764 | |
| dc.identifier.volume | 12 | |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Sage Publications Ltd. | |
| dc.relation.ispartof | Therapeutic Advances in Ophthalmology | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | Attribution-NonCommercial 4.0 International | * |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | * |
| dc.subject | Cornea | |
| dc.subject | Intravitreal Dexamethasone Implantation | |
| dc.subject | Topography | |
| dc.title | The corneal effects of intravitreal dexamethasone implantation | |
| dc.type | Article |
