Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?

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dc.authorid0000-0002-9704-6173
dc.authorid0000-0003-4292-5717
dc.authorid0000-0001-6494-8923
dc.contributor.authorYuluğ, Burak
dc.contributor.authorHanoğlu, Lütfü
dc.contributor.authorKılıç, Ertuğrul
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:42Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:42Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)
dc.descriptionWOS: 000412175800003
dc.descriptionPubMed ID: 28523718
dc.description.abstractSleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms of amyloid beta (A) clearance metabolism. Here, we aimed to evaluate the current evidence on the role of sleep deprivation in A clearance metabolism. To that end, we discuss possible mechanisms underlying the bidirectional interaction between the sleep deprivation and A clearance pathways.
dc.identifier.citationYuluğ, B., Hanoğlu, L. ve Kılıç, E. (2017). Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease? Psychiatry and Clinical Neurosciences, 71(10), 673-677. https://dx.doi.org/10.1111/pcn.12539
dc.identifier.doi10.1111/pcn.12539
dc.identifier.endpage677
dc.identifier.issn1323-1316
dc.identifier.issn1440-1819
dc.identifier.issue10
dc.identifier.scopusqualityQ1
dc.identifier.startpage673
dc.identifier.urihttps://dx.doi.org/10.1111/pcn.12539
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3712
dc.identifier.volume71
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPsychiatry and Clinical Neurosciencesen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAlzheimer's Disease
dc.subjectAmyloid Beta Clearance
dc.subjectGlymphatic System
dc.subjectSleep
dc.subjectSleep Deprivation
dc.titleDoes sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
dc.typeReview Article

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