Analysis of risk factors affecting coagulopathy after donor hepatectomy in a newly established liver transplant center

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dc.authorid0000-0002-6745-0159
dc.authorid0000-0001-7581-6424
dc.contributor.authorAktaş, Sema
dc.contributor.authorSevmiş, Şinasi
dc.contributor.authorŞeker, Mehmet
dc.contributor.authorKorkut, Esin
dc.contributor.authorKarakayalı, Hamdi
dc.date.accessioned08.07.201910:49:13
dc.date.accessioned2019-07-08T20:18:33Z
dc.date.available08.07.201910:49:13
dc.date.available2019-07-08T20:18:33Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: As might be expected, living donor liver surgery is associated with serious morbidity and mortality risks. Coagulopathy after donor hepatectomy is an important risk factor affecting morbidity. In this study, risk factors affecting the development of coagulopathy after donor hepatectomy was evaluated in a newly-established liver transplant center. Material and Methods: A retrospective evaluation of 46 liver donors to whom hepatectomy was applied in Medipol Universty of School of Medicine Department of Organ Transplantation between April 2014 and July 2015 was made. Coagulopathy was defined as prothrombin time >=15 sec. or platelet count <80000/mm3 on postoperative day 3. Donors were separated into 2 groups as those with (n=24) and without (n=22) coagulopathy. Preoperative, intraoperative and postoperative factors acting on coagulopathy were analyzed. Results: In the intergroup analysis, it was seen that remnant liver volume, remnant liver volume % and remnant liver volume to body weight ratio were factors associated with coagulopathy. The cut-off values for these 3 parameters were calculated as 773.5cm3, 40.5% and 0.915 cm3/kg, respectively. Only remnant liver volume % was determined as a risk factor for coagulopathy after donor hepatectomy on multiple logistic regression analysis. Conclusion: The results of this study showed that the most important risk factors affecting coagulopathy after donor hepatectomy were the parameters associated with remnant liver volume.
dc.identifier.citationAktaş, S., Sevmiş, Ş., Şeker, M., Korkut, E. ve Karakayalı, H. (2017). Analysis of risk factors affecting coagulopathy after donor hepatectomy in a newly established liver transplant center. Turkish Journal of Surgery, 33(2), 69-75. https://dx.doi.org/10.5152/turkjsurg.2017.3352
dc.identifier.endpage75
dc.identifier.issn2564-6850
dc.identifier.issn2564-7032
dc.identifier.issue2
dc.identifier.scopusqualityQ3
dc.identifier.startpage69
dc.identifier.urihttps://hdl.handle.net/20.500.12511/357
dc.identifier.urihttps://dx.doi.org/10.5152/turkjsurg.2017.3352
dc.identifier.volume33
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofTurkish Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDonor Hepatectomy
dc.subjectCoagulopathy
dc.subjectRemnant Liver
dc.subjectRisk Factors
dc.titleAnalysis of risk factors affecting coagulopathy after donor hepatectomy in a newly established liver transplant center
dc.typeArticle

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