Experiences of two centers in percutaneous ventricular septal defect closure using konar multifunctional occluder

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dc.authorid0000-0002-2947-6120
dc.authorid0000-0002-7779-4449
dc.authorid0000-0001-6602-5946
dc.authorid0000-0002-3105-5472
dc.contributor.authorKamalı, Hacer
dc.contributor.authorSivaslı Gül, Özlem
dc.contributor.authorÇoban, Şenay
dc.contributor.authorSarı, Gizem
dc.contributor.authorSarıtaş, Türkay
dc.contributor.authorErdem, Abdullah
dc.contributor.authorAldudak, Bedri
dc.date.accessioned2022-05-06T10:33:11Z
dc.date.available2022-05-06T10:33:11Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractBACKGROUND: Transcatheter closure of perimembraneous ventricular septal defect still poses a challenge due to the adjacent structures of the tricuspid and aortic valves and the risk of atrioventricular block. We report our experience at 2 centers using the KONAR-MF (multifunctional occluder) ventricular septal defect device, which gained its CE mark in May 2018. METHODS: A retrospective study was carried out on all patients who underwent transcatheter ventricular septal defect closure with the KONAR-MF (multifunctional occluder) ventricular septal defect device at 2 centers. RESULTS: A total of 47 patients were identified. The median age and weight of the patients were 25.8 months and 11 kg. The ventricular septal defects that were closed in 5 cases were post-operative hemodynamically significant residual ventricular septal defects. Forty-eight devices were used in the 47 cases. As for the location of the ventricular septal defect, 40/48 (83.33%) ventricular septal defects were perimembranous and 8/48 (16.66%) were muscular. The percutaneous device closure was successful in 46 procedures (95.8%). Device embolization was observed in 2 patients, and a significant residual shunt was observed in 2 cases. In the follow-up, there was no enhancement in the residual shunt in the remaining cases. Temporary atrioventricular block occurred in 2 cases during the procedure and improved after long sheath withdrawal. CONCLUSION: Soft, flexible, and low-profile KONAR-MF (multifunctional occluder) occluders ensure easy and safe implantation, and small sheath sizes allow for their use in small infants. Although near and mid-term follow-ups did not indicate any permanent atrioventricular block, a larger sample of patients and a longer follow-up period is necessary to understand long-term outcomes.
dc.identifier.citationKamalı, H., Sivaslı Gül, Ö., Çoban, Ş., Sarı, G., Sarıtaş, T., Erdem, A. ... Aldudak, B. (2022). Experiences of two centers in percutaneous ventricular septal defect closure using konar multifunctional occluder. Anatolian Journal of Cardiology, 26(4), 276-285. https://doi.org/10.5152/AnatolJCardiol.2021.464
dc.identifier.doi10.5152/AnatolJCardiol.2021.464
dc.identifier.endpage285
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue4
dc.identifier.pmid35435839
dc.identifier.scopus2-s2.0-85128794997
dc.identifier.scopusqualityQ3
dc.identifier.startpage276
dc.identifier.urihttps://doi.org/10.5152/AnatolJCardiol.2021.464
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9410
dc.identifier.volume26
dc.identifier.wos000791808300006en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorKamalı, Hacer
dc.institutionauthorÇoban, Şenay
dc.institutionauthorSarı, Gizem
dc.institutionauthorErdem, Abdullah
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofAnatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectAtrioventricular Block
dc.subjectPercutaneous VSD Closure
dc.subjectKONAR-MF (Multifunctional Occluder)
dc.titleExperiences of two centers in percutaneous ventricular septal defect closure using konar multifunctional occluder
dc.typeArticle

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