The stereology of the urinary bladder

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dc.authorid0000-0002-6984-3079
dc.contributor.authorUlubay, Mahmut
dc.contributor.authorAltun, Gamze
dc.contributor.authorKaplan, Arife Ahsen
dc.contributor.authorHamour, Hala Mahgoub
dc.contributor.authorKaplan, Süleyman
dc.date.accessioned2024-11-07T08:10:55Z
dc.date.available2024-11-07T08:10:55Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractQuantitative evaluation of the bladder wall structure can help evaluate pathological structures at morphological examination of the urinary bladder. Studies have applied stereological methods to radiological images and urinary bladder tissue specimen blocks embedded in paraffin. Volumetric evaluations of the bladder wall structure are particularly common. The wall structure of the urinary bladder consists of three layers, the epithelium plus lamina propria, muscular layer and adventitia/serosa layer. However, some studies also discuss the structure of the muscular mucosa and submucosa. The volume fractions of bladder wall components were calculated using a point-counting grid in a sample stereological study of the urinary bladder of diabetic rats. When the differences between the groups were subjected to statistical evaluation, no difference was observed between the groups in terms of the volume fraction of the mucosal layer, the muscular layer, or the serosa/adventitia layer. However, a remarkable increase was determined in the diabetes group at analysis of the ratio of blood vessels to the lamina propria (II) layer. These data were examined by considering the appropriate coefficient of error and coefficient of variation values. This chapter discusses in detail the stereological methods applied in the bladder and the histological structures examined, and the stereological results and restrictive steps of the sample study are also presented.
dc.identifier.citationUlubay, M., Altun, G., Kaplan, A. A., Hamour, H. M. ve Kaplan, S. (2024). The stereology of the urinary bladder. A Manual of the Stereological Techniques içinde (387-414. ss.). Nova Science Publishers, Inc.
dc.identifier.endpage414
dc.identifier.isbn9798891138940
dc.identifier.isbn9798891137707
dc.identifier.scopus2-s2.0-85201327179
dc.identifier.scopusqualityN/A
dc.identifier.startpage387
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12870
dc.indekslendigikaynakScopus
dc.institutionauthorKaplan, Arife Ahsen
dc.language.isoen
dc.publisherNova Science Publishers, Inc.
dc.relation.ispartofA Manual of the Stereological Techniquesen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCavalieri Method
dc.subjectPoint Counting Grid
dc.subjectSystematic Random Sampling
dc.subjectUrinary Bladder
dc.subjectVolume Fraction
dc.titleThe stereology of the urinary bladder
dc.typeBook Chapter

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