Occurrence of fumonisins B1 and B2 in homemade medicinal plants: Exposure assessment in Northern Turkey

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dc.contributor.authorGürer Soyoğul, Ümran
dc.contributor.authorOmurtag Korkmaz, İrem
dc.contributor.authorUlusoylu Dumlu, Melek
dc.contributor.authorOmurtag, Gülden Zehra
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:28Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:28Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Toksikoloji Ana Bilim Dalı
dc.description.abstractThis study was conducted to determine the recent level of contamination with Fumonisin B1 (FB1) and Fumonisin B2 (FB2) in major medicinal plants and to assess consumer exposure in northern Turkey. FB1 and FB2 were investigated by using high performance liquid chromatography (HPLC) with fluorescence detection after derivatization with o-phthaldialdehyde (OPA). A total of 78 homemade medicinal plant samples from 14 species were analysed. The recovery in thyme was 67.2±5.2% for FB1 and 80.8±14.3% for FB2 spiked with 1 µg g-1 of each analyte. The minimum detectable amount for the OPA derivatives of FB1 and FB2 were 1 ng per injection and 2.5 ng per injection, respectively. The limit of quantitation (LOQ) S/N=10 was 0.078 and 0.313 µg g-1, and the limit of detection (LOD) S/N=3 was 0.023 and 0.093 µg g-1 for FB1 and FB2, respectively. FB1 was detected in thyme (0.125) and mint (0.125 and 0.256 µg g-1) samples; however. FB2 toxin was below the detection limit in all samples. These results indicate that toxins might be present in homemade medicinal plants; however, the risk of exposure to fumonisins by the consumption of those plants was lower than the estimated TDI limits (<2 µg kg-1 bw).
dc.identifier.citationGürer Soyoğul, Ü., Omurtag Korkmaz, İ., Ulusoylu Dumlu, M. ve Omurtag, G. Z. (2016). Occurrence of fumonisins B1 and B2 in homemade medicinal plants: Exposure assessment in Northern Turkey. Acta Alimentaria, 45(1), 54-60. https://dx.doi.org/10.1556/066.2016.45.1.7
dc.identifier.doi10.1556/066.2016.45.1.7
dc.identifier.endpage60
dc.identifier.issn0139-3006
dc.identifier.issue1
dc.identifier.scopusqualityQ3
dc.identifier.startpage54
dc.identifier.urihttps://hdl.handle.net/20.500.12511/795
dc.identifier.urihttps://dx.doi.org/10.1556/066.2016.45.1.7
dc.identifier.volume45
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAkademiai Kiado Rt.
dc.relation.ispartofActa Alimentariaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDietary Intake
dc.subjectDried Plants
dc.subjectFusarium Toxins
dc.subjectHPLC
dc.titleOccurrence of fumonisins B1 and B2 in homemade medicinal plants: Exposure assessment in Northern Turkey
dc.typeArticle

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