Allergic sensitization in patients with pruritus sine materia in the absence of a somatic cause

Pekmezci, Erkin

Allergic sensitization in patients with pruritus sine materia in the absence of a somatic cause

dc.authorid	0000-0003-1469-2557
dc.contributor.author	Pekmezci, Erkin
dc.date.accessioned	2021-01-29T12:19:50Z
dc.date.available	2021-01-29T12:19:50Z
dc.date.issued	2020
dc.department	İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalı
dc.description.abstract	Aim: Pruritus sine materia in the absence of a somatic cause is generally attributed to psychogenic factors, but it is also well known that psychological stress may affect skin through its impacts on immune response. In this three-year retrospective study we aimed to reveal the allergic sensitization of patients with chronic pruritus without a somatic cause. Material and Methods: Three hundred and sixty five male and female patients with widespread chronic pruritus between 6 and 75 years old were retrospectively recruited. In addition to routine hematologic examination, skin prick test and serum total IgE measurement were performed on each patient. Results: In cutaneous examination, the patients had no visible manifestation except self excoriations in some, and all had normal values in hematologic laboratory examination. Altogether 10% of patients had positive results for both skin prick test and serum total IgE, and 42% of patients had positive results for either skin prick test and/or serum total IgE, which may be regarded as a presentation of immediate type hypersensitivity. Conclusion: Considering the quite high positive ratios obtained for both skin prick test and serum total IgE, it may be encouraging to perform these tests routinely on the patients with pruritus sine materia, both for revealing a probable allergic tendency and for better handling the treatment modalities.
dc.identifier.citation	Pekmezci, E. (2020). Allergic sensitization in patients with pruritus sine materia in the absence of a somatic cause. Annals of Medical Research, 27(1), 312-318. https://doi.org/10.5455/annalsmedres.2019.11.730
dc.identifier.doi	10.5455/annalsmedres.2019.11.730
dc.identifier.endpage	318
dc.identifier.issn	2636-7688
dc.identifier.issn	1300-1744
dc.identifier.issue	1
dc.identifier.startpage	312
dc.identifier.uri	https://doi.org/10.5455/annalsmedres.2019.11.730
dc.identifier.uri	https://hdl.handle.net/20.500.12511/6456
dc.identifier.volume	27
dc.indekslendigikaynak	TR-Dizin
dc.language.iso	en
dc.publisher	Annals of Medical Research Publishing Inc
dc.relation.ispartof	Annals of Medical Research	en_US
dc.relation.publicationcategory	Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	Pruritus Sine Materia
dc.subject	Skin Prick Test
dc.subject	Ige
dc.subject	Allergy
dc.title	Allergic sensitization in patients with pruritus sine materia in the absence of a somatic cause
dc.type	Article