Effects of mutational combinations on philadelphia-negative myeloproliferative neoplasms

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dc.contributor.authorYönal-Hindilerden, İpek
dc.contributor.authorDağlar-Aday, Aynur
dc.contributor.authorHindilerden, Fehmi
dc.contributor.authorNalcacı, Meliha
dc.contributor.authorAkif, Selim Yavuz
dc.contributor.authorSargın, Deniz
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:57:04Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:57:04Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000399199200015
dc.descriptionPubMed ID: 28360451
dc.description.abstractPhiladelphia-negative myeloproliferative neoplasms (MPNs) were first described 65 years ago. Yet, the molecular features of the disease have become of interest since 2005 following the identification of the JAK2V617F mutation.1 Between 90% and 98% of patients with polycythemia vera and about 50% of patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF) harbor the JAK2V617F mutation.2 In recent years, additional genetic factors such as the mutations of IDH1/2, TET2, EZH2, ASXL1, and CALR have been identified in Ph-negative MPNs.3 However, the significance of mutational combinations on Ph-negative MPNs remains unknown.
dc.identifier.citationYönal-Hindilerden, İ., Dağlar-Aday, A., Hindilerden, F., Nalcacı, M., Akif, S. Y. ve Sargın, D. (2017). Effects of mutational combinations on philadelphia-negative myeloproliferative neoplasms. Iranian Journal Medical Sciences, 42(2), 219-220.
dc.identifier.endpage220
dc.identifier.issn0253-0716
dc.identifier.issn1735-3688
dc.identifier.issue2
dc.identifier.scopusqualityQ3
dc.identifier.startpage219
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2891
dc.identifier.volume42
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherShiraz Univ Medical Sciences
dc.relation.ispartofIranian Journal Medical Sciencesen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMutational Combinations
dc.subjectPhiladelphia-Negative Myeloproliferative Neoplasms
dc.titleEffects of mutational combinations on philadelphia-negative myeloproliferative neoplasms
dc.typeLetter

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