Genetic testing and counseling challenges in personalized breast cancer care: review article with insights from Türkiye

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dc.authorid0000-0002-0443-6966
dc.contributor.authorÇiçin, İrfan
dc.contributor.authorKaradurmuş, Nuri
dc.contributor.authorBilici, Ahmet
dc.contributor.authorBahsi, Taha
dc.contributor.authorŞendur, Mehmet Ali
dc.contributor.authorDemirci, Umut
dc.contributor.authorGöksu, Sema Sezgin
dc.contributor.authorEr, Özlem
dc.contributor.authorBişgin, Atıl
dc.contributor.authorÖztürk Sağlam, Özge Fulya
dc.contributor.authorAver, Birkan
dc.contributor.authorKılıçkap, Saadettin
dc.date.accessioned2024-05-08T10:22:19Z
dc.date.available2024-05-08T10:22:19Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractAccording to current evidence, testing for germline BRCA pathogenic variants in newly diagnosed breast cancer (BC) patients has the potential to reduce the burden of the disease through targeted therapies and secondary prevention. A personalized approach to testing can lead to improved individual outcomes for patients. Despite the proven clinical utility and therapeutic impact of BRCA1/2 tests in shaping therapy for metastatic BC, awareness and access to these tests are limited in many developing countries, including Turkiye. This limitation impacts the healthcare economy as delayed or missed interventions can lead to increased long-term costs. The limited access is mainly due to fear of stigmatization among patients, country-specific legislation and costs, a lack of awareness, vagueness surrounding the tests and access restrictions. This review offers a perspective for policymakers and healthcare providers in Turkiye to establish pathways that integrate the patient experience into comprehensive care pathways and national cancer control plans.
dc.identifier.citationÇiçin, İ., Karadurmuş, N., Bilici, A., Bahsi, T., Şendur, M. A., Demirci, U. ... Kılıçkap, S. (2024). Genetic testing and counseling challenges in personalized breast cancer care: review article with insights from Türkiye. Future Oncology, 20(15). http://dx.doi.org/10.2217/fon-2023-0518
dc.identifier.doi10.2217/fon-2023-0518
dc.identifier.issn1479-6694
dc.identifier.issn1744-8301
dc.identifier.issue15
dc.identifier.pmid38014519
dc.identifier.scopus2-s2.0-85189376763
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.2217/fon-2023-0518
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12437
dc.identifier.volume20
dc.identifier.wos001114850700001en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBilici, Ahmet
dc.language.isoen
dc.relation.ispartofFuture Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBRCA Pathogenic Variant
dc.subjectBreast Cancer
dc.subjectGenetic Testing
dc.subjectHealthcare Economy
dc.subjectImproved Individual Outcomes
dc.subjectPersonal Approach
dc.titleGenetic testing and counseling challenges in personalized breast cancer care: review article with insights from Türkiye
dc.typeOther

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