Assessment of repolarization abnormalities in baseline electrocardiograms of patients with myocarditis

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dc.authorid0000-0001-5825-8627
dc.authorid0000-0002-4607-5724
dc.authorid0000-0001-9975-5507
dc.authorid0000-0003-1919-3183
dc.authorid0000-0003-0230-6575
dc.authorid0000-0002-4951-6716
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorBabür Güler, Gamze
dc.contributor.authorGüler, Ekrem
dc.contributor.authorDemir, Gültekin Günhan
dc.contributor.authorTeber, Mehmet Kamil
dc.contributor.authorKızılırmak, Filiz
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorBoztosun, Bilal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:03:49Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:03:49Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000414976900005
dc.descriptionPubMed ID: 29151301
dc.description.abstractBackground/aim: Myocarditis in the acute phase usually presents with sinus tachycardia but many other arrhythmias might be seen as well. In this study we aimed to investigate repolarization abnormalities in baseline ECG of patients with myocarditis for the first time. Materials and methods: Thirty patients diagnosed with myocarditis and 25 healthy age-matched controls were included. Two different cardiologists measured corrected QT (QTc), QT dispersion (QTd), QT peak (QTp), T wave peak to T wave end (TpTe), TpTe/QT ratio, and TpTe/QTc ratio in 12-lead ECG. Results: When compared with the control group, QTp (P:0.021), QT (P:0.003), TpTe (P < 0.001), TpTe/QTc ratio (P < 0.001), and TpTe/QT ratio (P:0.005) were significantly higher in patients with myocarditis. A comparison of receiver operating characteristic (ROC) curves was conducted using the Hanley and McNeil method. The area under the curve (AUC) of the electrocardiographic characteristics QT (AUC: 0.736; 95% CI [0.600-0.846]), QTP (AUC:0.680; 95% CI [0.540-0.799]), and TpTe (AUC:0.771; 95% CI [0.638-873]) and TpTe/QTc (AUC:0.774; 95% CI [0.641-0.876]) and TpTe/QT (AUC:0.726; 95% CI [0.589-0.838]) in myocarditis were not significantly different from each other but all of them were different from 0.5. Conclusion: Baseline ECGs of patients with myocarditis were associated with repolarization abnormalities. These novel findings may be one of the reasons underlying arrhythmic events in patients with myocarditis.
dc.identifier.citationGüneş, H. M., Babür Güler, G., Güler, E., Demir, G. G.,Teber, M. K., Kızılırmak, F. ... Boztosun, B. (2017). Assessment of repolarization abnormalities in baseline electrocardiograms of patients with myocarditis.Turkish Journal of Medical Sciences, 47(5), 1333-1339. https://dx.doi.org/10.3906/sag-1612-39
dc.identifier.doi10.3906/sag-1612-39
dc.identifier.endpage1339
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5
dc.identifier.scopusqualityQ3
dc.identifier.startpage1333
dc.identifier.urihttps://dx.doi.org/10.3906/sag-1612-39
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3948
dc.identifier.volume47
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTübitak Scientific and Technological Research Council of Turkey
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMyocarditis
dc.subjectRepolarization Abnormalities
dc.subjectTpTe
dc.titleAssessment of repolarization abnormalities in baseline electrocardiograms of patients with myocarditis
dc.typeArticle

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