Bridging the gap: a narrative review of osteoporosis disability, adipokines, and the role of AI in postmenopausal women

Tariq, Saba; Jabbar, Sohail; Ahmad, Awais; Tariq, Sundus

Bridging the gap: a narrative review of osteoporosis disability, adipokines, and the role of AI in postmenopausal women

dc.authorid	0000-0003-0083-1819
dc.contributor.author	Tariq, Saba
dc.contributor.author	Jabbar, Sohail
dc.contributor.author	Ahmad, Awais
dc.contributor.author	Tariq, Sundus
dc.date.accessioned	2024-07-11T07:18:51Z
dc.date.available	2024-07-11T07:18:51Z
dc.date.issued	2024
dc.department	İstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.department	İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstract	Osteoporosis is a global health concern characterized by reduced bone density and compromised bone quality, resulting in an increased risk of fractures, particularly in postmenopausal women. The assessment of bone mineral density (BMD) plays a pivotal role in diagnosing osteoporosis, as it accounts for approximately 70% of overall bone strength. The World Health Organization (WHO) has endorsed BMD measurement as a reliable method for diagnosing this condition. In Pakistan, the incidence of bone fractures is on the rise, largely attributable to an aging population and a range of contributing factors. Understanding the global and local prevalence of osteoporosis, its impact on morbidity and mortality, and the contributing factors is vital for developing effective preventive and therapeutic strategies. The role of adipokines, including chemerin, vaspin, and omentin-1, in bone metabolism is an emerging area of investigation. These adipokines play diverse roles in physiology, ranging from inflammation and metabolic regulation to cardiovascular health. Understanding their potential impact on bone health is a topic of ongoing research. The intricate relationship between bone density, bone quality, and overall bone strength is central to understanding the diagnosis and management of osteoporosis. Current innovation in machine learning and predictive model can bring revolution in the field of bone health and osteoporosis. Early identification of people with osteoporosis or risk of fracture through machine learning can prevent disability and improve the quality of life.
dc.description.sponsorship	Grant Support & Financial Disclosures: King Salman Center for Disability Research	en_US
dc.identifier.citation	Tariq, S., Jabbar, S., Ahmad, A. ve Tariq, S. (2024). Bridging the gap: a narrative review of osteoporosis disability, adipokines, and the role of AI in postmenopausal women. Pakistan Journal of Medical Sciences, 40(7), 1572-1577. http://dx.doi.org/10.12669/pjms.40.7.9072
dc.identifier.doi	10.12669/pjms.40.7.9072
dc.identifier.endpage	1577
dc.identifier.issn	1682-024X
dc.identifier.issn	1681-715X
dc.identifier.issue	7
dc.identifier.pmid	39092029
dc.identifier.scopus	2-s2.0-85197242764
dc.identifier.scopusquality	Q3
dc.identifier.startpage	1572
dc.identifier.uri	http://dx.doi.org/10.12669/pjms.40.7.9072
dc.identifier.uri	https://hdl.handle.net/20.500.12511/12711
dc.identifier.volume	40
dc.identifier.wos	001272260200046	en_US
dc.identifier.wosquality	Q2
dc.indekslendigikaynak	Web of Science
dc.indekslendigikaynak	Scopus
dc.indekslendigikaynak	PubMed
dc.institutionauthor	Tariq, Sundus
dc.language.iso	en
dc.relation.ec	info:eu-repo/grantAgreement/EC/FP7/KSRG-2023-443
dc.relation.ispartof	Pakistan Journal of Medical Sciences	en_US
dc.relation.publicationcategory	Makale
dc.rights	info:eu-repo/semantics/openAccess
dc.rights.uri	http://creativecommons.org/licenses/by/3.0	*
dc.subject	Adipokines
dc.subject	Artificial Intelligence
dc.subject	BMD
dc.subject	Osteoporosis
dc.title	Bridging the gap: a narrative review of osteoporosis disability, adipokines, and the role of AI in postmenopausal women
dc.type	Other