Frequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO)

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dc.authorid0000-0002-4091-6465
dc.contributor.authorTanrıverdi, Elif
dc.contributor.authorTutar, Nuri
dc.contributor.authorŞentürk, Ayşegül
dc.contributor.authorBahadır, Ayşe
dc.contributor.authorAksel, Nimet
dc.contributor.authorYetkin, Nur Aleyna
dc.contributor.authorKaradeniz, Gülistan
dc.contributor.authorÇetin, Nazlı
dc.contributor.authorTabaru, Ali
dc.contributor.authorYıldırım, Binnaz Zeynep
dc.contributor.authorSelimoğlu Şen, Hatice
dc.contributor.authorÖzçelik, Neslihan
dc.contributor.authorÖzsarı, Emine
dc.contributor.authorUzer, Fatih
dc.contributor.authorÇİçek, Tuğba
dc.contributor.authorEsendağlı, Dorina
dc.contributor.authorHocanlı, İclal
dc.contributor.authorDurmuş Koçak, Nagihan
dc.contributor.authorTapan, Utku
dc.contributor.authorKurt, Bahar
dc.contributor.authorArınç, Sibel
dc.contributor.authorKavas, Murat
dc.contributor.authorŞahin, Füsun
dc.contributor.authorErgun, Dilek
dc.contributor.authorYılmazel Uçar, Elif
dc.contributor.authorKılıç, Talat
dc.contributor.authorGülmez, İnci
dc.contributor.authorÇeldir Emre, Jülide
dc.contributor.authorDoğan, Deniz
dc.contributor.authorÖzdemir, Fatma
dc.contributor.authorDüger, Mustafa
dc.contributor.authorAlzafer, Süha
dc.contributor.authorYarar, Esra
dc.contributor.authorSerçe Unat, Damla
dc.contributor.authorSalık, Bilge
dc.date.accessioned2022-04-08T11:13:23Z
dc.date.available2022-04-08T11:13:23Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and beneficial in terms of bleeding; however, studies that present up-to-date life data are necessary. Aims: To evaluate the frequency of using DOACs, which are prescribed with a limited number of indications in our country, and real-life data results. Study Design: Cross-sectional study Methods: This cross-sectional survey collected the clinical data (history, current treatment, treatment duration, etc.) of patients with pulmonary thromboembolism and who applied to the physician for follow-up between October 15, 2019, and March 15, 2020. The researchers kept the patient records sequentially. Results: Data from 836 patients with acute pulmonary thromboembolism from 25 centers were collected, and DOAC was used in 320 (38.5%) of them. The most preferred DOAC was rivaroxaban (n = 294, 91.9%). DOAC was mostly preferred because it could not provide an effective INR level with warfarin (n=133, 41.6%). Bleeding was observed in 13 (4%) patients. Conclusion: The use of direct oral anticoagulants is becoming almost as widespread as conventional therapy. Real-life data results are important for their contribution to clinical practice.
dc.identifier.citationTanrıverdi, E., Tutar, N., Şentürk, A., Bahadır, A., Aksel, N., Yetkin, N. A. ... Salık, B. (2022). Frequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO). Balkan Medical Journal, 39(2), 148-152. https://doi.org/10.4274/balkanmedj.galenos.2021.2021-10-19
dc.identifier.doi10.4274/balkanmedj.galenos.2021.2021-10-19
dc.identifier.endpage152
dc.identifier.issn2146-3123
dc.identifier.issue2
dc.identifier.pmid35330566
dc.identifier.scopus2-s2.0-85127062858
dc.identifier.scopusqualityQ3
dc.identifier.startpage148
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.galenos.2021.2021-10-19
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9269
dc.identifier.volume39
dc.identifier.wos000779560300009en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorDüger, Mustafa
dc.language.isoen
dc.publisherGalenos Publishing House
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectTUPEDO
dc.subjectDirect Oral Anticoagulants
dc.subjectPulmonary Thromboembolism
dc.titleFrequency of direct oral anticoagulants usage in acute pulmonary thromboembolism treatment in Turkey (TUPEDO)
dc.typeArticle

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