Intraspinal pathology

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dc.authorid0000-0003-1447-9051
dc.contributor.authorAkalan, Nejat
dc.contributor.authorMacyszyn, Luke
dc.contributor.authorHwang, Steven W.
dc.contributor.authorSamdani, Amer F.
dc.date.accessioned2023-05-24T11:05:01Z
dc.date.available2023-05-24T11:05:01Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.description.abstractThe term "spinal dysraphism" covers two types of spinal congenital malformations, traditionally grouped as "open" and "closed" forms. These two groups have almost no features in common, including their embryological origin, presentation, natural history, and treatment algorithm. Open spinal dysraphism or myelomeningocele is primarily a neural tube closure defect, resulting with a more or less very stereotypic lesion and clinical presentation. The aim of treatment is to preserve the neurological and clinical status of the newborn. Closed spinal dysraphism is far more complicated and is represented by various forms of different combinations of mesodermal structures. While the neurological impairment in myelomeningocele is straightforward related to the incomplete differentiation of the neural tissue, the mechanisms of neurological impairment in closed dysraphisms are far more complex and controversial. This complexity, in turn, generates an ongoing controversy in establishing universal algorithms for treatment.
dc.identifier.citationAkalan, N., Macyszyn, L., Hwang, S. W. ve Samdani, A. F. (2022). Intraspinal pathology. The Growing Spine: Management of Spinal Disorders in Young Children: Third Edition içinde (261-272. ss.). Springer International Publishing. https://doi.org/10.1007/978-3-030-84393-9_17
dc.identifier.doi10.1007/978-3-030-84393-9_17
dc.identifier.endpage272
dc.identifier.isbn9783030843939
dc.identifier.isbn9783030843922
dc.identifier.scopus2-s2.0-85154618627
dc.identifier.scopusqualityN/A
dc.identifier.startpage261
dc.identifier.urihttps://doi.org/10.1007/978-3-030-84393-9_17
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10973
dc.indekslendigikaynakScopus
dc.institutionauthorAkalan, Nejat
dc.language.isoen
dc.publisherSpringer International Publishing
dc.relation.ispartofThe Growing Spine: Management of Spinal Disorders in Young Children: Third Editionen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectClosed (Occult) Dysraphism
dc.subjectLipomyelomeningocele
dc.subjectMyelomeningocele
dc.subjectNeural Tube Defect
dc.subjectOpen Dysraphism
dc.subjectSpinal Dermal Sinus
dc.titleIntraspinal pathology
dc.typeBook Chapter

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