DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey

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dc.authorid0000-0002-2018-9619
dc.authorid0000-0001-8422-3188
dc.contributor.authorBeceren, Ayfer
dc.contributor.authorAkdemir, Nebahat
dc.contributor.authorOmurtag, Gülden Zehra
dc.contributor.authorTatlıpınar, Mücteba Eşref
dc.contributor.authorŞardaş, Semra
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:15Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:15Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Toksikoloji Ana Bilim Dalı
dc.description37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 -- 25 August 2015 through 29 August 2015 -- 116805
dc.description.abstractThe refueling of vehicles is a major source of volatile organic compounds generated by used and evaporated fuel. Gasoline workers are directly exposed to various fuel products via many routes in the ambient air. The aim of this study is to determine the potential DNA damage in the peripheral blood samples of the gasoline station workers in Istanbul, Turkey by using the alkaline comet assay. Blood samples were collected from exposed workers (n= 25) and healthy controls (n= 14) with no history of occupational exposure. Significant difference in the mean total comet scores (TCS) of gasoline station workers (89.24 ± 30.83) were observed as compared with the control group (15.64 ± 16.17) (p < 0.001). Results from our study indicate that exposure to petrol vapour induce genotoxic effects, confirming that the gasoline station workers have a high risk of cancer due to their daily occupational exposure.
dc.identifier.citationBeceren, A., Akdemir, N., Omurtag, G. Z., Tatlıpınar, M. E. ve Şardaş, S. (2016). DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey. Acta Pharmaceutica Sciencia, 54(1), 53-62. https://dx.doi.org/10.23893/1307-2080.APS.0545
dc.identifier.doi10.23893/1307-2080.APS.0545
dc.identifier.endpage62
dc.identifier.issn1307-2080
dc.identifier.issue1
dc.identifier.scopusqualityN/A
dc.identifier.startpage53
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1108
dc.identifier.urihttps://dx.doi.org/10.23893/1307-2080.APS.0545
dc.identifier.volume54
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherUniversity of Istanbul
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectComet Assay
dc.subjectDNA Damage
dc.subjectFuel Exposure
dc.subjectGasoline Station Workers
dc.titleDNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey
dc.typeArticle

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