Beyond Mohs surgery and excisions: A focused review of treatment options for subtypes of basal cell carcinoma

Basit Öğe Kaydı
dc.contributor.authorAltun, Ece
dc.contributor.authorSchwartzman, Gabrielle
dc.contributor.authorCartron, Alexander M.
dc.contributor.authorKhachemoune, Amor
dc.date.accessioned2021-03-18T06:10:48Z
dc.date.available2021-03-18T06:10:48Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalı
dc.description.abstractBasal cell carcinoma (BCC) is the most common nonmelanoma skin cancer. It originates from undifferentiated cells in the basal cell layer of the epidermis or from the outer root sheath of the hair follicle. The most important factor in development of BCC is ultraviolet radiation. Surgery is considered the gold standard of treatment for BCC. However, nonsurgical options are available for individuals who are unsuitable for surgery. The purpose of this review is to summarize the efficacy and indications of alternative, nonsurgical treatments that can be used in the management of BCC. An extensive literature review was performed for the nonsurgical options for the treatment of BCC. Resources searched included PubMed and Google Scholars, limited to the years 1995 to 2020. Key words searched included BCC, destructive methods, photodynamic therapy (PDT), radiotherapy, topical medication, laser, hedgehog pathway inhibitors (HPIs). The most relevant results such as systematic reviews, randomized controlled trials, or comparative studies were selected to provide a summary for the most common nonsurgical methods used for treating BCC. Effective nonsurgical treatments for BCC include destructive methods (eg, curettage alone, cryosurgery, or electrodessication), PDT, topical medications, radiotherapy, laser, and HPIs. Nonsurgical therapeutic alternatives are safe and effective for the treatment of BCC. Factors such as tumor location, size, and histopathological subtype should be taken into consideration when selecting optimal treatment. In addition to clinical factors, cosmetic results and patient preference should be considered.
dc.identifier.citationAltun, E., Schwartzman, G., Cartron, A. M. ve Khachemoune, A. (2021). Beyond Mohs surgery and excisions: A focused review of treatment options for subtypes of basal cell carcinoma. Dermatologic Therapy, 34(1). https://dx.doi.org/10.1111/dth.14476
dc.identifier.doi10.1111/dth.14476
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1111/dth.14476
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6613
dc.identifier.volume34
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofDermatologic Therapyen_US
dc.relation.publicationcategoryDiÄŸer
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBasal Cell Carcinoma
dc.subjectDestructive Methods
dc.subjectHedgehog Pathway Inhibitors
dc.subjectLaser
dc.subjectPhotodynamic Therapy
dc.subjectRadiotherapy
dc.subjectTopical Medication
dc.titleBeyond Mohs surgery and excisions: A focused review of treatment options for subtypes of basal cell carcinoma
dc.typeReview Article

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
Ä°sim:
Altun- Ece-2021.pdf
Boyut:
921.76 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
Ä°ndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
Ä°sim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
Ä°ndir

Koleksiyon

Diğer Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu