The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies

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dc.authorid0000-0002-9704-6173
dc.authorid0000-0003-4292-5717
dc.authorid0000-0001-7566-1063
dc.authorid0000-0001-6494-8923
dc.contributor.authorYuluğ, Burak
dc.contributor.authorHanoğlu, Lütfü
dc.contributor.authorTavlı, Ahmet Mithat
dc.contributor.authorYılmaz Helvacı, Nesrin
dc.contributor.authorKılıç, Ertuğrul
dc.date.accessioned2020-07-17T12:18:24Z
dc.date.available2020-07-17T12:18:24Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractThere are rapidly replicating human data suggesting the therapeutic and neurorestorative role of repetitive transcranial magnetic stimulation (rTMS) in clinical depression. However there are only limited experimental studies in the literature and the neurobiological mechanisms of the technique are still unclear. Studies have suggested that modulating of either excitatory or inhibitory neural circuitry may be responsible for the mechanism of action of rTMS while it is still unclear whether rTMS exerts a neuroprotective effect. In the light of these findings, we aimed to review the neuroprotective effect of rTMS in animal models of depression. We have shown that rTMS may exert significant neuroprotective effect through acting on the oxidative injury, stress hormones, dopamine and serotonin levels, Brain Derived Neurotrophic Factor expression, neuroinflamation and hippocampal cell proliferation.
dc.identifier.citationYuluğ, B., Hanoğlu, L., Tavlı, A. M., Yılmaz Helvacı, N. ve Kılıç, E. (2016). The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies. Medicinal Chemistry, 12(6), 500-505. https://dx.doi.org/10.2174/1573406411666151005110321
dc.identifier.doi10.2174/1573406411666151005110321
dc.identifier.endpage505
dc.identifier.issue6
dc.identifier.scopusqualityQ3
dc.identifier.startpage500
dc.identifier.urihttps://dx.doi.org/10.2174/1573406411666151005110321
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5559
dc.identifier.volume12
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBentham Science Publishers
dc.relation.ispartofMedicinal Chemistryen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTranscranial Magnetic Stimulation
dc.subjectNeuroprotection
dc.subjectDepression
dc.titleThe brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies
dc.typeReview Article

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