The relationship between calcium metabolism parameters

dc.authorid0000-0002-0947-9498
dc.contributor.authorYıldız, Saliha
dc.contributor.authorÖztürk, Mustafa
dc.date.accessioned2019-12-26T17:11:57Z
dc.date.available2019-12-26T17:11:57Z
dc.date.issued2019
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBlood calcium is under very tight control in a narrow range of 8.5-10.5 mg/dl. We aimed to investigate the factors that contributed to this control. 464 females and 254 males aged 16-96 years were examined retrospectively. PTH, 25OH vitamin D, Ca, Mg, P and spot urine calcium, creatinine levels were examined. The rates were as follow; hypercalcemia 5.6%, primary hyperparathyroidism 10.4%, secondary hyperparathyroidism 40.8%, tertiary hyperparathyroidism 17.5%, normal PTH hypercalcemia 1.25%, hypocalcemia 13.5%, hypoparathyroidism 3.7%, hypovitaminosis D 77.6%, hypophosphatemia 6.4%, hyperphosphatemia 17.5%, hypomagnesemia 17.5%, hypermagnesemia 10.4%. Severe vitamin D deficiency was found as 37% (n= 172) in females and 20% (n= 53) in males (p <0.01). Urinary Ca and urine creatinine 25 OH vitamin D cut-off value was 10 ng/ml and it was 13ng/ml for PTH. While vitamin D was 10-20 ng/ml, urine Ca/creatinine ratio was lowest and it increased after 20 ng/ml in females and 30 ng/ml in males. There was a negative correlation with PTH as Ca decreased from 8.3 mg/dl and a positive correlation when it increased above 9.2 mg/ dl. Mg correlated positively with PTH, Ca and P (p= 0.00 r= 0.23, p= 0.007 r= 0.13, p= 0.00 r= 0.21, respectively). Mg was found to be significantly correlated with all parameters and 25 OH vitamin D was not correlated with any parameters. On the other hand, we have determined the threshold values where the parameters interact with each other.
dc.identifier.citationYıldız, S. ve Öztürk, M. (2019). The relationship between calcium metabolism parameters. Eastern Journal of Medicine, 24(4), 490-496. http://doi.org/10.5505/ejm.2019.46873
dc.identifier.doi10.5505/ejm.2019.46873
dc.identifier.endpage496
dc.identifier.issn1301-0883
dc.identifier.issue4
dc.identifier.scopusqualityQ4
dc.identifier.startpage490
dc.identifier.urihttp://doi.org/10.5505/ejm.2019.46873
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4739
dc.identifier.volume24
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherYüzüncü Yıl Üniversitesi Tıp Fakültesi
dc.relation.ispartofEastern Journal of Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCalcium
dc.subjectPoshphor
dc.subjectMagnesium
dc.subject25 OH Vitamin D
dc.subjectParathormone
dc.titleThe relationship between calcium metabolism parameters
dc.typeArticle

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