Infections in the immune interplay of inflammatory bowel disease

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dc.authorid0000-0002-7413-3426
dc.authorid0009-0001-6715-2872
dc.authorid0000-0002-7919-1326
dc.contributor.authorSeida, İsa
dc.contributor.authorBalcıoğlu, Zeynep Betül
dc.contributor.authorNeyestani, Kamyar
dc.contributor.authorMahroum, Naim
dc.date.accessioned2024-05-16T07:41:48Z
dc.date.available2024-05-16T07:41:48Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractInflammatory bowel disease (IBD), namely ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic, relapsing, multi-factorial disease characterized by inflammation of the intestine. While the etiology of IBD is still not fully understood, the incidence and prevalence of it are growing rapidly worldwide. IBD commonly peaks in the second-to-fourth decade of life, affecting men and women similarly. Early-life events, such as antibiotic administration and babies born by caesarian section, represent just a few among multiple environmental risk factors. In addition, gut microbiome was found to play a critical role in the pathogenesis of the disease. This is particularly important due to the interplay between the immune system and gut microbiome. Disorders of gut microbiome, such as “dysbiosis,” has commonly been seen in IBD patients. The role of microbes, both, in the initiation and exacerbation of disease, and protection from IBD are viewed in this chapter.
dc.identifier.citationSeida, İ., Balcıoğlu, Z. B., Neyestani, K. ve Mahroum, N. (2024). Infections in the immune interplay of inflammatory bowel disease. Infection and Autoimmunity (Third Edition) içinde (823-840. ss.). Academic Press. http://dx.doi.org/10.1016/B978-0-323-99130-8.00011-8
dc.identifier.doi10.1016/B978-0-323-99130-8.00011-8
dc.identifier.endpage840
dc.identifier.isbn9780323991308
dc.identifier.isbn9780323991315
dc.identifier.scopus2-s2.0-85189589403
dc.identifier.scopusqualityN/A
dc.identifier.startpage823
dc.identifier.urihttp://dx.doi.org/10.1016/B978-0-323-99130-8.00011-8
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12464
dc.indekslendigikaynakScopus
dc.institutionauthorSeida, İsa
dc.institutionauthorBalcıoğlu, Zeynep Betül
dc.institutionauthorNeyestani, Kamyar
dc.institutionauthorMahroum, Naim
dc.language.isoen
dc.publisherAcademic Press
dc.relation.ispartofInfection and Autoimmunityen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCrohn's Disease
dc.subjectDysbiosis
dc.subjectGut Microbiota
dc.subjectInflammatory Bowel Disease
dc.subjectUlcerative Colitis
dc.titleInfections in the immune interplay of inflammatory bowel disease
dc.typeBook Chapter

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