Other lesions of the corpus callosum

Other less common lesions can be detected in the corpus callosum (CC) in addition to well-known lesions. These pathologies include CC atrophy in chronic alcoholism, CC changes in high-altitude cerebral edema (HACE), and Virchow-Robin spaces. Atrophy and tissue loss can be detected in the CC in chronic alcoholics. Lesions in the CC due to microbleeding can be detected in HACE. The Virchow-Robin spaces are associated with age and lacunar infarcts but are generally not expected to cause neurological deterioration. In this chapter, we will mention about the age and gender groups in which these lesions are common neuroimaging features, frequently involved parts of the CC, and pathophysiology of these lesions.