A single tertiary center outcomes on cannulation strategies and extracorporeal membrane oxygenation in the treatment of respiratory failure during COVID-19 infection

dc.authorid0000-0001-9919-8392
dc.authorid0000-0002-2901-4807
dc.authorid0000-0001-5485-5440
dc.authorid0000-0003-4741-7877
dc.authorid0000-0001-6643-9364
dc.authorid0000-0001-6182-5055
dc.contributor.authorUlukan, Mustafa Özer
dc.contributor.authorKarakaya, Atalay
dc.contributor.authorYıldız, Yahya
dc.contributor.authorÖztaş, Didem Melis
dc.contributor.authorKamilçelebi, Nurdan
dc.contributor.authorÖzdemir, Servet
dc.contributor.authorUğurlucan, Murat
dc.contributor.authorErkanlı, Korhan
dc.date.accessioned2021-08-13T08:27:45Z
dc.date.available2021-08-13T08:27:45Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractAim: Extracorporeal membrane oxygenation (ECMO) is an important option for the management of severe acute respiratory distress syndrome (ARDS) in Coronavirus disease-2019 (COVID-19) cases. We aimed to present our experiences of ECMO in patients with respiratory failure secondary to COVID-19. Methods: Data of 22 consecutive COVID-19 patients with severe respiratory failure whom were supported with ECMO were collected from computer-based hospital software retrospectively. Patients were treated in a single medical center between April 23, 2020 and February 14, 2021. Patients were analyzed from the points of laboratory and inflammatory markers, ventilation and ECMO features. Results: The ages of patients were between 30 and 69 years (mean age: 56.3±10.63). All patients were under maximum ventilator support, with the prone position. All patients had elevated levels of inflammatory indicators as D-dimer and ferritin. The mean level of ferritin was 1, 564±1, 611 ng/mL. D-dimer value was maximum 10.000 mg/mL (mean: 5, 215±3, 104), CRP increased to 177 mg/L (mean: 159±71). Percent of lymphocytes decreased as low as 2% (mean: 4.16±2.10). The mean duration of veno-arterial (VA) ECMO was 1.6±0.94 days whereas, for veno-venous (VV) ECMO, it was 10.05±5 days. VA ECMO was decided due to cardiovascular collapse. Four patients with VA ECMO survived a maximum of 3 days. Four of (22.22%) of 18 VV ECMO supported patient’s blood gas values were at normal ranges, 3 of them needed tracheostomy, and all of could be discharged from the hospital. Conclusion: Although, ECMO support for severe respiratory failure patients with COVID-19 is more challenging than regular ECMO applications, especially VV ECMO usage should be reminded as a remedy.
dc.identifier.citationUlukan, M. Ö., Karakaya, A., Yıldız, Y., Öztaş, D. M., Kamilçelebi, N., Özdemir, S. ... Erkanlı, K. (2021). A single tertiary center outcomes on cannulation strategies and extracorporeal membrane oxygenation in the treatment of respiratory failure during COVID-19 infection. The Medical Bulletin of Haseki, 59, 25-30. https://dx.doi.org/10.4274/haseki.galenos.2021.7144
dc.identifier.doi10.4274/haseki.galenos.2021.7144
dc.identifier.endpage30
dc.identifier.issn1302-0072
dc.identifier.scopusqualityQ4
dc.identifier.startpage25
dc.identifier.urihttps://dx.doi.org/10.4274/haseki.galenos.2021.7144
dc.identifier.urihttps://hdl.handle.net/20.500.12511/7813
dc.identifier.volume59
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos
dc.relation.ispartofThe Medical Bulletin of Hasekien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectExtracorporeal Membrane Oxygenation
dc.subjectMulti-Organ Failure
dc.titleA single tertiary center outcomes on cannulation strategies and extracorporeal membrane oxygenation in the treatment of respiratory failure during COVID-19 infection
dc.typeArticle

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